中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
生物物理研究所 [7]
上海神经科学研究所 [6]
心理研究所 [5]
上海药物研究所 [4]
昆明动物研究所 [3]
过程工程研究所 [2]
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OAI收割 [31]
iSwitch采集 [2]
内容类型
期刊论文 [32]
学位论文 [1]
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2023 [1]
2020 [1]
2018 [2]
2017 [3]
2016 [1]
2015 [3]
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Biochemist... [7]
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浏览/检索结果:
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Euphejolkinolide A, a new ent-abietane lactone from Euphorbia peplus L. with promising biological activity in activating the autophagy-lysosomal pathway
期刊论文
OAI收割
HELIYON, 2023, 卷号: 9, 期号: 2, 页码: e13691
作者:
Ran,Xiaoqian
;
Lu,Qing-Yun
;
Li,Ying-Yao
;
Pu,Xue-Xue
;
Guo,Yarong
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/07/30
Euphorbia peplus L
Euphorbiaceae
Ent-abietane diterpenoid
Euphejolkinolide A
Autophagy-lysosomal pathway
ALZHEIMERS-DISEASE
TAU PATHOLOGY
NEURODEGENERATION
DITERPENOIDS
INHIBITION
MECHANISMS
APOPTOSIS
CELASTROL
PROTEIN
SYSTEM
Discovery of nitazoxanide-based derivatives as autophagy activators for the treatment of Alzheimer's disease
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2020, 卷号: 10, 期号: 4, 页码: 646-666
作者:
Li, Xiaokang
;
Lu, Jian
;
Xu, Yixiang
;
Wang, Jiaying
;
Qiu, Xiaoxia
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2020/07/01
Alzheimer's disease
Autophagy
Nitazoxanide
beta-amyloid
Tau protein
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia
期刊论文
OAI收割
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10, 页码: 15
作者:
Ji, Mei
;
Xie, Xi-xiu
;
Liu, Dong-qun
;
Yu, Xiao-lin
;
Zhang, Yue
  |  
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2018/07/17
Alzheimer's Disease
Frontotemporal Dementia
Hepatitis b Core Protein
Truncated Tau
Neurofibrillary Tangles
Virus-like Particles (Vlps)
Vaccine
Hepatitis B core VLP-based mis-disordered tau vaccine elicits strong immune response and alleviates cognitive deficits and neuropathology progression in Tau. P301S mouse model of Alzheimer's disease and frontotemporal dementia
期刊论文
OAI收割
ALZHEIMERS RESEARCH & THERAPY, 2018, 卷号: 10
作者:
Ji, M
;
Xie, XX
;
Liu, DQ
;
Yu, XL
;
Zhang, Y
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2018/12/29
Alzheimer's Disease
Virus-like Particles
Frontotemporal Dementia
In-vivo
Hepatitis b Core Protein
Neurofibrillary Degeneration
Truncated Tau
Corticobasal Degeneration
Neurofibrillary Tangles
Structural Determinants
Virus-like Particles (Vlps)
Truncated Tau
Vaccine
Immunotherapy
Protein
Pathology
Tauopathy
阿尔兹海默病的治疗研究及猕猴自发模型的筛选鉴定
学位论文
OAI收割
北京: 中国科学院大学, 2017
作者:
何夏萍
  |  
收藏
  |  
浏览/下载:71/0
  |  
提交时间:2019/09/16
阿尔兹海默病,甲醛,白藜芦醇, Tau 蛋白,gsk-3β,camkii,pp2a
Alzheimer’s Disease, Formaldehyde, Resveratrol, Tau Protein, Gsk3β, Camkii, Pp2a
阿尔兹海默病,猕猴,动物模型,自然发生动物模型
Alzheimer's Disease,spontaneous Disease Model,animal Model,rhesus Monkey
Resveratrol Attenuates Formaldehyde Induced Hyperphosphorylation of Tau Protein and Cytotoxicity in N2a Cells
期刊论文
OAI收割
Frontiers in Neuroscience, 2017, 卷号: 10, 期号: 0, 页码: 598
作者:
He, Xiaping
;
Li, Zhenhui
;
Rizak, Joshua D.
;
Wu, Shihao
;
Wang, Zhengbo
收藏
  |  
浏览/下载:55/0
  |  
提交时间:2017/03/13
Alzheimer's disease
formaldehyde
resveratrol
tau protein
GSK-3 beta
CaMKII
PP2A
Resveratrol Attenuates Formaldehyde Induced Hyperphosphorylation of Tau Protein and Cytotoxicity in N2a Cells
期刊论文
OAI收割
Frontiers in Neuroscience, 2017, 卷号: 10, 期号: X, 页码: e598
作者:
He XP
;
Li ZH
;
He RQ
;
Su M
;
Qin DD[*]
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2017/02/20
Alzheimer's disease
CaMKII
GSK-3β
PP2A
formaldehyde
resveratrol
tau protein
Escitalopram attenuates beta-amyloid-induced tau hyperphosphorylation in primary hippocampal neurons through the 5-HT1A receptor mediated Akt/GSK-3 beta pathway
期刊论文
OAI收割
ONCOTARGET, 2016, 卷号: 7, 期号: 12, 页码: 13328-13339
作者:
Wang YJ
;
Ren QG[*]
;
Li XL
;
Wu FF
;
Bai F
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2016/07/20
Alzheimer's disease
tau protein
escitalopram
Akt/GSK-3 beta pathway
5-HT1A receptor
Gerotarget
Ribosylation triggering Alzheimer's disease-like Tau hyperphosphorylation via activation of CaMKII
期刊论文
OAI收割
AGING CELL, 2015, 卷号: 14, 期号: 5, 页码: 754-763
作者:
Wei, Yan
;
Han, Chanshuai
;
Wang, Yujing
;
Wu, Beibei
;
Su, Tao
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2015/12/07
hyperphosphorylation
ribosylation
Tau protein
A beta regulation-based multitarget strategy for drug discovery against Alzheimer's disease
期刊论文
OAI收割
REVIEWS IN THE NEUROSCIENCES, 2015, 卷号: 26, 期号: 1, 页码: 13-30
作者:
Guo, Xiaodan
;
Jiang, Wei
;
Li, Chenjing
;
Zhu, Zhiyuan
;
Shen, Xu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2019/01/08
acetyl cholinesterase
Alzheimer's disease
autophagy
beta-amyloid
ER stress
lifespan
multitarget
oxidative stress
secretase
tau protein