中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [92]
上海神经科学研究所 [16]
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期刊论文 [182]
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Oxytocin inhibits the activity of acid-sensing ion channels through the vasopressin-1a receptor in primary sensory neurons1
期刊论文
OAI收割
出版物, 3111, 期号: 0, 页码: 1-34
作者:
Fang Qiu
;
Chun-Yu Qiu
;
Huilan Cai
;
Ting-Ting Liu
;
Zu-Wei Qu
  |  
收藏
  |  
浏览/下载:474/0
  |  
提交时间:2017/07/24
Oxytocin
Acid-sensing Ion Channel
Proton-gated Current
Vasopressin-1a Receptor
Dorsal Root Ganglion Neuron
Electrophysiology
Pain
Adapter protein 2-modulated μ-opioid receptor trafficking in paraventricular thalamus contributes to fentanyl contextual addiction memory in mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 9
作者:
Li, Yu-jie
;
Chen, Ruo-song
;
Zan, Gui-ying
;
Song, Ying-cai
;
Huang, Xue-ying
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2026/01/28
fentanyl
contextual addiction memory
paraventricular thalamus
mu-opioid receptor trafficking
Ap2a1
Divergent activation patterns of BRS3 revealed by two Chinese herb-derived agonists
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 10, 页码: 5231-5243
作者:
Li, Jie
;
Li, Changyao
;
Zhou, Qingtong
;
Han, Wei
;
Fang, Mingzhu
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2025/12/04
Bombesin receptor subtype-3
Cryo-EM
Structural pharmacology
Unliganded
Chinese herb DSO-5a
Oridonin
Receptor activation
Drug discovery
An efficient deep learning-based strategy to screen inhibitors for GluN1/GluN3A receptor
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 9
作者:
Wang, Ze-chen
;
Zeng, Yue
;
Sun, Jin-yuan
;
Chen, Xue-qin
;
Wu, Hao-chen
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2025/04/24
deep learning
scoring function
GluN1/GluN3A receptor
N
-methyl-
D
-aspartate (NMDA) receptor
virtual screening
drug discovery
REG3A secreted by peritumoral acinar cells enhances pancreatic ductal adenocarcinoma progression via activation of EGFR signaling
期刊论文
OAI收割
CELL COMMUNICATION AND SIGNALING, 2025, 卷号: 23, 期号: 1, 页码: 19
作者:
Ren, Xiaojing
;
Teng, Yunfei
;
Xie, Kunxin
;
He, Xiao
;
Chen, Gang
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2025/04/01
REG3A
Pancreatic ductal adenocarcinoma
Peritumoral acinar cell
Epidermal growth factor receptor (EGFR)
Paracrine
Discovery of pyridazinone derivatives bearing tetrahydroimidazo[1,2-
a
] pyrazine scaffold as potent inhibitors of transient receptor potential canonical 5 to ameliorate hypertension-induced renal injury in rats
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 275, 页码: 18
作者:
Xu, Yuanyuan
;
Ren, Younan
;
Zhang, Jie
;
Niu, Bo
;
Liu, Mengru
  |  
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2024/08/22
Pyridazinone
Tetrahydroimidazo[1,2-a]pyrazine
Transient receptor potential canonical 5
Chronic kidney disease
Focal segmental glomerulosclerosis
The antidepressant-like effect and proposed mechanism of action of TPN672MA, a novel serotonin-dopamine receptor modulator for the treatment of schizophrenia
期刊论文
OAI收割
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR, 2024, 卷号: 242, 页码: 13
作者:
Cheng, Jiaxin
;
Wu, Chunhui
;
Wang, Yu
;
Wang, Zhen
;
He, Yang
  |  
收藏
  |  
浏览/下载:61/0
  |  
提交时间:2024/09/24
TPN672MA
5-HT 1A receptor agonist
D 2 /D 3 receptor partial agonist
5-HT 2A receptor antagonist
Antidepressant-like
Mechanism
The mechanism of low molecular weight fucoidan-incorporated nanofiber scaffolds inhibiting oral leukoplakia via SR-A/Wnt signal axis
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2024, 卷号: 15, 页码: 17
作者:
Xu, Ming
;
Sun, Yu
;
Cong, Beibei
;
Zhang, Xiaopei
;
Li, Zhenfeng
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2024/08/30
fucoidan
electrospun nanofiber
oral leukoplakia
scavenger receptor A
Wnt/beta-catenin
Cannabidiol exhibits anxiolytic-like effects and antipsychotic-like effects in mice models
期刊论文
OAI收割
NEUROSCIENCE LETTERS, 2024, 卷号: 826, 页码: 8
作者:
Shu, Guangzhao
;
He, Yang
;
Suo, Jin
;
Wu, Chunhui
;
Gong, Xudong
  |  
收藏
  |  
浏览/下载:78/0
  |  
提交时间:2024/06/27
Cannabidiol
Stress-induced hyperthermia
Phencyclidine-induced negative symptoms of
schizophrenia model
5-HT 1A receptor
Application of ensemble learning for predicting GABA
A
receptor agonists
期刊论文
OAI收割
COMPUTERS IN BIOLOGY AND MEDICINE, 2024, 卷号: 169, 页码: 13
作者:
Xiao, Fu
;
Ding, Xiaoyu
;
Shi, Yan
;
Wang, Dingyan
;
Wang, Yitian
  |  
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2024/03/25
GABA(A )receptor
Benzodiazepine
Agonist
Machine learning
Classification