中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [33]
心理研究所 [10]
上海生物化学与细胞生... [7]
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期刊论文 [68]
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2025 [2]
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1 [1]
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Discovery of indole derivatives as STING degraders
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 21
作者:
An, Yuxiang
;
Zhang, Yan
;
Luo, Xin
;
Lan, Yaohan
;
Geng, Meiyu
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/08/20
Autoimmune diseases
Degrader
Inflammatory
PROTAC
STING
Immunosuppressive nitrogen-containing triterpenoid saponins from
Mussaenda
erosa
and the therapeutic efficacy of heinsiagenin A in a murine lupus erythematosus model
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2025, 卷号: 163, 页码: 11
作者:
Xu, Yidan
;
Xiang, Mai
;
Chang, Yuan
;
Chen, Zhenhua
;
Zhang, Rujun
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2025/08/20
Mussaenda erosa
Nitrogen-containing triterpenoid saponins
Immunosuppressive activity
Autoimmune diseases
Heinsiagenin A
Discovery and optimization of 3-(indolin-5-yloxy)pyridin-2-amine derivatives as potent necroptosis inhibitors
期刊论文
OAI收割
ARCHIV DER PHARMAZIE, 2024, 页码: 21
作者:
Lan, Yaohan
;
Ji, Yinchun
;
Peng, Xia
;
Duan, Wenhu
;
Geng, Meiyu
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2024/08/22
autoimmune disease
necroptosis inhibitor
pharmacokinetic profile
receptor interacting protein kinase 1 (RIPK1)
structural optimization
Prevalence and clinical correlates of suicide attempts in patients with first-episode drug-na?ve major depressive disorder and comorbid autoimmune thyroiditis
期刊论文
OAI收割
BJPSYCH OPEN, 2024, 卷号: 10, 期号: 3, 页码: 7
作者:
Luo, Yinli
;
Zhou, Yanan
;
Peng, Pu
;
Yuan, Ning
;
Zhang, Xiangyang
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2024/05/27
Anxiety
autoimmune thyroiditis
major depressive disorder
suicide attempts
first-episode drug-na & iuml
ve
TPN10475 Constrains Effector T Lymphocytes Activation and Attenuates Experimental Autoimmune Encephalomyelitis Pathogenesis by Facilitating TGF-β Signal Transduction
期刊论文
OAI收割
JOURNAL OF NEUROIMMUNE PHARMACOLOGY, 2024, 卷号: 19, 期号: 1, 页码: 16
作者:
Wang, Chun
;
Jiang, Xiangrui
;
Lv, Jie
;
Zhuang, Wei
;
Xie, Ling
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2024/04/09
Experimental autoimmune encephalomyelitis
TGF-beta signal transduction
Effector CD4(+) T cells activation
Th/Treg
Cell migration
Autoantibodies against eukaryotic translation elongation factor 1 delta in two patients with autoimmune cerebellar ataxia
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2024, 卷号: 14, 页码: 8
作者:
Guo, Liyuan
;
Ren, Haitao
;
Fan, Siyuan
;
Chao, Xingchen
;
Liu, Mange
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/03/04
autoimmune
cerebellar ataxia
biomarker
novel autoantibody
anti-EEF1D antibody
Autoimmune diseases: targets, biology, and drug discovery
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Li, Shu-jie
;
Wu, Yan-li
;
Chen, Juan-hua
;
Shen, Shi-yi
;
Duan, Jia
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2024/01/26
autoimmune disease
autoantigen
immunotherapy
type 1 diabetes
insulin
drug discovery
The novel small molecule TPN10518 alleviates EAE pathogenesis by inhibiting AP1 to depress Th1/Th17 cell differentiation
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2023, 卷号: 123, 页码: 12
作者:
Xie, Ling
;
Lv, Jie
;
Saimaier, Kaidireya
;
Han, Sanxing
;
Han, Mengyao
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2023/10/17
TPN10518
Th1/Th17 cells
AP1
Experimental autoimmune encephalomyelitis
Discovery of novel triazine derivatives as potent retinoic acid receptor-related orphan receptor gamma t (ROR gamma t) inverse agonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 256, 页码: 18
作者:
Lu, Lixue
;
Chen, Song
;
Yu, Mingcheng
;
Zhou, Ronghui
;
Guo, Siqi
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2023/10/17
ROR gamma t
Triazines
Inverse agonist
Psoriasis
Autoimmune diseases
ARID3a from the ARID family: structure, role in autoimmune diseases and drug discovery
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Guo, Cheng-cen
;
Xu, H. Eric
;
Ma, Xiong
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
transcription factors
ARID
ARID3a
autoimmune diseases
systemic lupus erythematosus
primary biliary cholangitis