中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [21]
昆明植物研究所 [5]
长春应用化学研究所 [4]
金属研究所 [2]
近代物理研究所 [2]
上海神经科学研究所 [1]
更多
采集方式
OAI收割 [37]
iSwitch采集 [1]
内容类型
期刊论文 [38]
发表日期
2024 [1]
2023 [2]
2022 [3]
2020 [1]
2019 [1]
2016 [1]
更多
学科主题
Biochemist... [6]
Pharmacolo... [6]
Chemistry [3]
Biophysics [2]
Biochemist... [1]
Chemistry,... [1]
更多
筛选
浏览/检索结果:
共38条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
发表日期升序
发表日期降序
Rational Design and Synthesis of Novel Benzimidazole Derivatives as Potential
β
-Glucosidase Inhibitors
期刊论文
OAI收割
LETTERS IN DRUG DESIGN & DISCOVERY, 2024, 卷号: 21, 期号: 13, 页码: 2674-2683
作者:
Liu, Xu
;
Sun, Ge
;
Li, Fengxing
;
Feng, Xia
;
Jia, Tongguan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/11/05
beta-glucosidase inhibitors
benzimidazole
linker
solvent-exposed region
o-trihydroxyphenol
iminosugar
The extracts of Lobaria pindarensis, an edible lichen from Himalayas, suppress inflammatory response and fibrillation of amyloid β-protein in cultured microglial cells: Active depsidones, norstictic acid and stictic acid, are responsible for the functions
期刊论文
OAI收割
JOURNAL OF FUNCTIONAL FOODS, 2023, 卷号: 107, 页码: 105607
作者:
Yang,Mei-Xia
;
Cheng,Edwin Hok-Chi
;
Ospondpant,Dusadee
;
Tung,Ka-Ki
;
Wang,Li-Song
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/07/25
Alzheimer's disease
Inflammation
Fibrillar A beta
Lichen
Lobaria pindarensis
Depsidone
IN-SILICO
IDENTIFICATION
INHIBITORS
Small-Molecule Drugs in Immunotherapy
期刊论文
OAI收割
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23, 期号: 13, 页码: 1341-1359
作者:
Hao,Xuanrun
;
Chen,Zhongliang
;
Li,Haining
;
Wei,Minqin
;
Zuo,Zhili
  |  
收藏
  |  
浏览/下载:174/0
  |  
提交时间:2024/07/25
Cancer immunotherapy
inhibitors
Pd-1/Pd-L1 inhibitor
IDO inhibitor
STING agonists
ROR gamma t agonists
TGF
beta inhibitors
INDOLEAMINE 2,3-DIOXYGENASE
SIGNALING INHIBITOR
DENDRITIC CELLS
GROWTH
TUMOR
PATHWAY
PEMBROLIZUMAB
RECEPTORS
DISCOVERY
VADIMEZAN
Development and structure-activity relationships of tanshinones as selective 11beta-hydroxysteroid dehydrogenase 1 inhibitors
期刊论文
OAI收割
Natural products and bioprospecting, 2022, 卷号: 12, 期号: 1, 页码: 36
作者:
Deng, Xu
;
Huang, Su-Ling
;
Ren, Jian
;
Pan, Zheng-Hong
;
Shen, Yu
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2024/03/15
Metabolic syndrome
Selective 11beta-HSD1 inhibitors
Structure-activity relationships
Tanshinones
Effect of PD-1 Inhibitor Combined with X-Ray Irradiation on the Inflammatory Microenvironment and Lung Tissue Injury in Mice
期刊论文
OAI收割
JOURNAL OF INFLAMMATION RESEARCH, 2022, 卷号: 15, 页码: 545-556
作者:
Geng, Yichao
;
Su, Shengfa
;
Cao, Li
;
Yang, Ting
;
Ouyang, Weiwei
  |  
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2022/04/11
PD-1 inhibitors
radiotherapy
radiation fibrosis
lung injury
transforming growth factor-beta 1
Synthesis and biological evaluation of (20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol derivatives as alpha-glucosidase and PTP1B inhibitors
期刊论文
OAI收割
MEDICINAL CHEMISTRY RESEARCH, 2022, 卷号: 31, 期号: 2, 页码: 350-367
作者:
Yang, Xiao-Tong
;
Li, Tian-Ze
;
Geng, Chang-An
;
Liu, Pei
;
Chen, Ji-Jun
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/04/30
(20S,24R)-epoxy-dammarane-3 beta,12 beta,25-triol
alpha-glucosidase inhibitors
PTP1B inhibitors
Enzyme kinetics
TYROSINE-PHOSPHATASE 1B
DIABETES-MELLITUS
EPIDEMIOLOGY
DGAT1 inhibitors protect pancreatic beta-cells from palmitic acid-induced apoptosis
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 8
作者:
Huang, Jun-shang
;
Guo, Bin-bin
;
Wang, Gai-hong
;
Zeng, Li-min
;
Hu, You-hong
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2020/12/24
type 2 diabetes
DGAT1 inhibitors
pancreatic beta-cells
apoptosis
ER stress
inflammation
Transforming growth factor beta signaling pathway: A promising therapeutic target for cancer
期刊论文
OAI收割
JOURNAL OF CELLULAR PHYSIOLOGY, 2019, 页码: 12
作者:
Yang, Hongying
;
Zhang, Hong
;
Zhang, Qianjing
;
Zhang, Jinhua
;
Xu, Caipeng
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2019/11/10
clinical application
drug
inhibitors
TGF-beta
tumor
Platinum-coordinated graphitic carbon nitride nanosheet used for targeted inhibition of amyloid beta-peptide aggregation
期刊论文
iSwitch采集
Nano research, 2016, 卷号: 9, 期号: 8, 页码: 2411-2423
作者:
Li, Meng
;
Guan, Yijia
;
Chen, Zhaowei
;
Gao, Nan
;
Ren, Jinsong
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2019/05/09
Amyloid disease
Platinum
Graphitic carbon nitride nanosheet
Photooxygenation
Amyloid beta-peptide (a beta) inhibitors
Design, Synthesis, and Pharmacological Evaluation of Highly Potent and Selective Dipeptidyl Peptidase-4 Inhibitors
期刊论文
OAI收割
ARCHIV DER PHARMAZIE, 2015, 卷号: 348, 期号: 6, 页码: 399-407
作者:
Jiang, Tao
;
Zhou, Yuren
;
Zhu, Jianming
;
Chen, Zhuxi
;
Sun, Peng
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2019/01/08
beta-Homophenylalanine
DPP-4
Drug design
Inhibitors
P2-binding moiety