机构

• 上海药物研究所 [5]
• 昆明动物研究所 [1]

采集方式

• OAI收割 [6]

内容类型

• 期刊论文 [6]

发表日期

• 2016 [1]
• 2014 [1]
• 2013 [1]
• 2010 [1]
• 2008 [2]

学科主题

筛选

浏览/检索结果: 共6条，第1-6条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Discovery and Structure-Activity Relationship Study of 4-Phenoxythiazol-5-carboxamides as Highly Potent TGR5 Agonists 期刊论文  OAI收割 CHEMICAL & PHARMACEUTICAL BULLETIN, 2016, 卷号: 64, 期号: 4, 页码: 326-339 作者:  Chen, Zhixiang;  Ning, Mengmeng;  Zou, Qingan;  Cao, Hua;  Ye, Yangliang   |  收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 Takeda G-protein-coupled receptor 5 agonist  bioisostere  microsomal clearance  structure-activity relationship   4-Quinolone-3-carboxylic acids as cell-permeable inhibitors of protein tyrosine phosphatase 1B 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2014, 卷号: 22, 期号: 14, 页码: 3670-3683 作者:  Zhi, Ying;  Gao, Li-Xin;  Jin, Yi;  Tang, Chun-Lan;  Li, Jing-Ya   |  收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 Protein tyrosine phosphatase 1B inhibitor  4-Quinolone-3-carboxylic acid  Bidentate ligand  Bioisostere  Insulin receptor signaling   Design, synthesis and SAR of piperidyl-oxadiazoles as 11 beta-hydroxysteroid dehydrogenase 1 inhibitors 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2013, 卷号: 62, 页码: 1-10 作者:  Xia, Guangxin;  You, Xiaodi;  Liu, Lin;  Liu, Haiyan;  Wang, Jianfa   |  收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 11 beta-HSD1 inhibitor  Oxadiazole  Bioisostere  SAR  Docking   Discovery of novel (S)-alpha-phenyl-gamma-amino butanamide containing CCR5 antagonists via functionality inversion approach 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2010, 卷号: 20, 期号: 7, 页码: 2219-2223 作者:  Zhang, Hu-Shan;  Feng, Dong-Zhi;  Chen, Li;  Long, Ya-Qiu   |  收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 CCR5 antagonist  HIV-1 entry inhibitor  Functionality inversion  Bioisostere  Butanamide  Tropane  2-Methyl-3H-imidazo[4,5-b]pyridine  3H-[1,2,3]Triazolo[4,5-b]pyridine   Efficient synthesis and utilization of phenyl-substituted heteroaromatic carboxylic acids as aryl diketo acid isosteres in the design of novel HIV-1 integrase inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, 卷号: 18, 期号: 16, 页码: 4521-4524 作者:  Zeng, Li-Fan;  Zhang, Hu-Shan;  Wang, Yun-Hua;  Sanchez, Tino;  Zheng, Yong-Tang   |  收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08 HIV-1 integrase inhibitor  bioisostere  heteroaromatic carboxylic acid  isoxazole  isothiazole  1H-pyrazole  bioavailability  antiviral effect   Efficient synthesis and utilization of phenyl-substituted heteroaromatic carboxylic acids as aryl diketo acid isosteres in the design of novel HIV-1 integrase inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, 卷号: 18, 期号: 16, 页码: 4521-4524 作者:  Zeng LF;  Zhang HS;  Wang YH;  Sanchez T;  Zheng YT 收藏  |  浏览/下载：26/0  |  提交时间：2010/08/24 HIV-1 integrase inhibitor  bioisostere  heteroaromatic carboxylic acid  isoxazole  isothiazole  1H-pyrazole  bioavailability  antiviral effect