中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共18条,第1-10条 帮助

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Terpenoids from Nardostachys jatamansi and Their Cytotoxic Activity against Human Pancreatic Cancer Cell Lines 期刊论文  OAI收割
Phytochemistry, 2022, 期号: 200, 页码: 113228
作者:  
Li-Mei Ma;  Kai Wang;  Xian-Hua Meng;  Yi-Dan Zheng;  Cheng-Bo Wang
  |  收藏  |  浏览/下载:37/0  |  提交时间:2022/11/30
Sensitive profiling of cell surface proteome by using an optimized biotinylation method 期刊论文  OAI收割
JOURNAL OF PROTEOMICS, 2019, 卷号: 196, 页码: 33-41
作者:  
Li, Yanan;  Wan, Yan;  Mao, Jiawei;  Yao, Yating;  Wang, Keyun
  |  收藏  |  浏览/下载:68/0  |  提交时间:2019/06/20
Sensitive profiling of cell surface proteome by using an optimized biotinylation method 期刊论文  iSwitch采集
Journal of proteomics, 2019, 卷号: 196, 页码: 33-41
作者:  
Li, Yanan;  Wan, Yan;  Mao, Jiawei;  Yao, Yating;  Wang, Keyun
收藏  |  浏览/下载:108/0  |  提交时间:2019/05/08
Efficacy of green nanoparticles against cancerous and normal cell lines: a systematic review and meta-analysis 期刊论文  iSwitch采集
Iet nanobiotechnology, 2018, 卷号: 12, 期号: 4, 页码: 377-391
作者:  
Barabadi, Hamed;  Alizadeh, Ahad;  Ovais, Muhammad;  Ahmadi, Amirhossein;  Shinwari, Zabta Khan
收藏  |  浏览/下载:73/0  |  提交时间:2019/04/23
A new aromatic glycoside and its anti-proliferative activities from the leaves of Bergenia purpurascens 期刊论文  OAI收割
NATURAL PRODUCT RESEARCH, 2018, 卷号: 32, 期号: 6, 页码: 668-675
作者:  
Zhang, Shan-Shan;  Liao, Zhi-Xin;  Huang, Ri-Zhen;  Gong, Cheng-Cheng;  Ji, Lan-Ju
  |  收藏  |  浏览/下载:54/0  |  提交时间:2018/07/25
Novel cytotoxic benzophenones from Garcinia paucinervis identified by UPLC-QTOF-MSE 期刊论文  OAI收割
PLANTA MEDICA, 2016, 卷号: 82, 页码: 1
作者:  
Li, P.;  Senthilkumar, H. Anandhi;  Figueroa, M.;  Wu, S. B.;  Fata, J. E.
  |  收藏  |  浏览/下载:21/0  |  提交时间:2017/12/11
Folate-polyethylene glycol conjugated carboxymethyl chitosan for tumor-targeted delivery of 5-fluorouracil 期刊论文  OAI收割
MOLECULAR MEDICINE REPORTS, 2014, 卷号: 9, 期号: 3, 页码: 786—792
Li, HL; He, YX; Gao, QH; Wu, GZ
收藏  |  浏览/下载:26/0  |  提交时间:2015/03/13
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文  OAI收割
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  
Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
收藏  |  浏览/下载:44/0  |  提交时间:2015/05/14
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)  one of the major components isolated from the traditional  Chinese medicine Rubia yunnanensis  exhibited inhibitory activity on the proliferation of several  human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay  and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle  arrest in human cervical carcinoma HeLa cells. Further  MTA was found to induce apoptosis of HeLa cells  through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and  release of cytochrome c into the cytosol  which caused the cleavage of caspase and poly(ADP-ribose)  polymerase and finally triggered the apoptosis. Furthermore  the p53/p21/Cdc2-cyclin B1 signaling was  found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of  cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused  the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of  R. yunnanensis  a folk anti-cancer herb used in Yunnan  China.  
Establishment and characterization of primary lung cancer cell lines from Chinese population 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2011, 卷号: 32, 期号: 3, 页码: 385-392
作者:  
Zheng, C;  Sun, YH;  Ye, XL;  Chen, HQ;  Ji, HB
收藏  |  浏览/下载:24/0  |  提交时间:2015/07/22