中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [763]
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Dehydrocurvularin-loaded mPEG-PLGA nanoparticles for targeted breast cancer drug delivery: preparation, characterization,
in vitro
, and
in vivo
evaluation
期刊论文
OAI收割
JOURNAL OF DRUG TARGETING, 2024, 卷号: 32, 期号: 3, 页码: 325-333
作者:
Cui, Xuewei
;
He, Zhong
;
Liang, Jianjia
;
Wei, Mulan
;
Guo, Zhiyong
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/06
Dehydrocurvularin
nanoparticles
breast cancer
solubility
tumour targeting
Proteomics analysis of histone deacetylase inhibitor-resistant solid tumors reveals resistant signatures and potential drug combinations
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:
Hao, Bing-bing
;
Ma, Ke
;
Xu, Jun-yu
;
Fan, Ru-feng
;
Zhao, Wen-si
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/03/25
solid tumor
histone deacetylase inhibitor
vorinostat (SAHA)
drug resistance
proteomics
Structure-Activity Relationships of 2-(Arylthio)benzoic Acid FTO Inhibitors
期刊论文
OAI收割
ISRAEL JOURNAL OF CHEMISTRY, 2024, 页码: 13
作者:
Yan, Chao
;
Zhang, Qian
;
Xiao, Pan
;
Xie, Xinyun
;
Li, Ming
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2024/03/25
RNA modification
m(6)A
FTO
anticancer
Steric repulsion introduced by loop constraints modulates the microphase separation of chromatins
期刊论文
OAI收割
JOURNAL OF CHEMICAL PHYSICS, 2024, 卷号: 160, 期号: 5, 页码: 9
作者:
Wei, Jiachen
;
Xue, Yue
;
Liu, Yawei
;
Tian, Hao
;
Shao, Yingfeng
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/11
Discovery of a potent and selective covalent threonine tyrosine kinase (TTK) inhibitor
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 143, 页码: 16
作者:
Sun, Yaoliang
;
Chen, Zhiwen
;
Liu, Guobin
;
Chen, Xiaoai
;
Shi, Zihan
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/25
Inhibitor
Cancer
Threonine tyrosine kinase (TTK)
Covalent
Discovery and Optimization of WDR5 Inhibitors via Cascade Deoxyribonucleic Acid-Encoded Library Selection Approach
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 67, 期号: 2, 页码: 1079-1092
作者:
Qin, Shaozhao
;
Feng, Lijian
;
Zhao, Qingyi
;
Yan, Ziqin
;
Lyu, Xilin
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/02/27
Targeting ST8SIA6-AS1 counteracts KRAS
G12C
inhibitor resistance through abolishing the reciprocal activation of PLK1/c-Myc signaling
期刊论文
OAI收割
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023, 卷号: 12, 期号: 1, 页码: 22
作者:
Wang, Yafang
;
Yao, Mingyue
;
Li, Cheng
;
Yang, Kexin
;
Qin, Xiaolong
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/26
KRAS(G12C)
c-Myc
PLK1
LncRNA
ST8SIA6-AS1
Drug resistance
Discovery of Dual Function Agents That Exhibit Anticancer Activity via Catastrophic Nicotinamide Adenine Dinucleotide Depletion
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16694-16703
作者:
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/26
Discovery of 5-trifluoromethyl-2-aminopyrimidine derivatives as potent dual inhibitors of FLT3 and CHK1
期刊论文
OAI收割
RSC MEDICINAL CHEMISTRY, 2023, 页码: 14
作者:
Deng, Minjie
;
Gao, Yue
;
Wang, Peipei
;
Du, Wenjing
;
Xu, Gaoya
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/02/19
Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025
作者:
Cheng, Jing
;
Yan, Ziqin
;
Jiang, Kailong
;
Liu, Chen
;
Xu, Dehua
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2024/02/19