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CAS IR Grid
机构
上海药物研究所 [13]
金属研究所 [5]
上海生物化学与细胞生... [3]
水生生物研究所 [2]
武汉病毒研究所 [1]
昆明植物研究所 [1]
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OAI收割 [25]
iSwitch采集 [2]
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期刊论文 [27]
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2016 [2]
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Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856
作者:
Liu, Wen
;
Yin, Ye
;
Wang, Meijing
;
Fan, Ting
;
Zhu, Yuyu
  |  
收藏
  |  
浏览/下载:98/0
  |  
提交时间:2020/12/24
Src homology 2 domain containing tyrosine phosphatase-2 (SHP2)
hepatic steatosis
insulin resistance
caspase-1
interleukin 18 (IL-18)
fatty liver
metabolic disorder
inflammation
cytokine signaling
caspase 1 (CASP1)
tyrosine-protein phosphatase (tyrosine phosphatase)
macrophage
microRNA-149 targets caspase-2 in glioma progression
期刊论文
OAI收割
ONCOTARGET, 2016, 卷号: 7, 期号: 18, 页码: 26388-26399
作者:
Shen, Xiaokun
;
Li, Jie
;
Liao, Wenfeng
;
Wang, Jiwen
;
Chen, Huanjun
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
glioma
microRNA-149
caspase-2
p53
FS-108,an Hsp90 inhibitor,impairs survival and motility of oncogene addicted cancer cells
期刊论文
OAI收割
Chinese Pharmacological Bulletin, 2016, 卷号: 32, 期号: 10, 页码: 1357-1363
作者:
Ping Fangfang
;
Wang Yueqin
;
Zhang Minmin
;
Shi Feng
;
Chen Danqi
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2019/01/08
Hsp90
caspase-3
Hsp90
EBC-1 and A375 cells
G_2/M arrest
apoptosis
Caspase-3
migration
Ca2+ and caspases are involved in hydroxyl radical-induced apoptosis in erythrocytes of Jian carp (Cyprinus carpio var. Jian)
期刊论文
OAI收割
FISH PHYSIOLOGY AND BIOCHEMISTRY, 2015, 卷号: 41, 期号: 5, 页码: 1305-1319
作者:
Li, HuaTao
;
Feng, Lin
;
Jiang, WeiDan
;
Liu, Yang
;
Jiang, Jun
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2015/11/05
Fish erythrocyte
Apoptosis
Ca2+
Caspase
PS exposure
DNA fragmentation
High-dose thalidomide increases the risk of peripheral neuropathy in the treatment of ankylosing spondylitis
期刊论文
OAI收割
Neural Regeneration Research, 2015, 卷号: 10, 期号: 5, 页码: 814-818
作者:
Xue Hongxia
;
Fu Wenyi
;
Cui Huadong
;
Yang Lili
;
Zhang Ning
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2021/02/02
active zone stability
Drosophila
neuromuscular junction
dephosphorylation
Liprin-α
Syd-1
PP2A
GSK-3?
living scaffolds
neural tissue engineering
cell transplant
biomaterials
regeneration
neurotrauma
neurodegeneration
axon pathfinding
cell migration
injury
plasticity
neurodegenerative disease
brain
therapy
neuron
microglia
neural progenitor
tissue engineering
neuroregeneration
repair
central nervous system
biomaterial
regenerative medicine
nanotechnology
spinal cord injury
axonal regeneration
exosome
extracellular vesicle
microRNA
microvesicle
nerve gap
neurite outgrowth
peripheral nerve injury
Schwann cell
stem cell
hemodynamic phases
cerebral subarachnoid hemorrhage
metabolic crises
nerve regeneration
hypoxic-ischemic brain damage
ginsenoside Rg1
neural stem cells
cell transplantation
cell differentiation
cognition
nerve reconstruction
neural regeneration
nerve regeneration
brain injury
neuroimaging
functional magnetic resonance imaging
regional homogeneity
apoplexy
subacute
ischemia
participants
healthy
volunteers
brain activity
NSFC grants
neural regeneration
nerve regeneration
brain injury
neuroprotection
cerebral ischemia/reperfusion injury
lateral intracerebroventricular injection
Apelin-13
nerve apoptosis
Bcl-2
caspase-3
NSFC grants
neural regeneration
nerve regeneration
fractalkine
CX3 chemokine receptor 1
neuronal maturation
dendrites
doublecortin
synaptic maturation
newborn neurons
neural regeneration
nerve regeneration
neurodegenerative diseases
Alzheimer′s disease
transgenic animal models
mice
epimedium herb
milkvetch root
kudzuvine root
divalent metal transporter 1
ferroportin 1
neural regeneration
nerve regeneration
microRNA-124
neurogenesis
neuronal survival
Huntington′s disease
SRY-related HMG box transcription factor 9
brain-derived neurotrophic factor
peroxisome proliferator-activated receptor gamma coactivator 1-alpha
mutant huntingtin
nerve regeneration
Ras/Raf/Erk1/2 signaling pathway
spinal cord injury
apoptosis
repair
regulation
inhibition
neural regeneration
nerve regeneration
neurogenic bladder
bibliometric analysis
Web of Science database
visualization analysis
CiteSpace III
citation analysis
neural regeneration
nerve regeneration
sciatic nerve injury
autologous nerve grafting
epineurial suturing
three-dimensional finite element models
load
stress
displacement
neural regeneration
nerve regeneration
brain injury
facial palsy
Bell′s palsy
comparison
methodological quality
therapy
fixed effect model
acupuncture
incomplete recovery
randomized controlled trials
electroacupuncture
NSFC grants
neural regeneration
nerve regeneration
peripheral nerve injury
thalidomide
ankylosing spondylitis
adverse reactions
peripheral neuropathy
treatment
dose
treatment time
age
sex
neural regeneration
Neurology. Diseases of the nervous system
RC346-429
prospective study
High-dose thalidomide increases the risk of peripheral neuropathy in the treatment of ankylosing spondylitis
期刊论文
OAI收割
Neural Regeneration Research, 2015, 卷号: 10, 期号: 5, 页码: 814-818
作者:
Xue Hongxia
;
Fu Wenyi
;
Cui Huadong
;
Yang Lili
;
Zhang Ning
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2021/02/02
active zone stability
Drosophila
neuromuscular junction
dephosphorylation
Liprin-α
Syd-1
PP2A
GSK-3?
living scaffolds
neural tissue engineering
cell transplant
biomaterials
regeneration
neurotrauma
neurodegeneration
axon pathfinding
cell migration
injury
plasticity
neurodegenerative disease
brain
therapy
neuron
microglia
neural progenitor
tissue engineering
neuroregeneration
repair
central nervous system
biomaterial
regenerative medicine
nanotechnology
spinal cord injury
axonal regeneration
exosome
extracellular vesicle
microRNA
microvesicle
nerve gap
neurite outgrowth
peripheral nerve injury
Schwann cell
stem cell
hemodynamic phases
cerebral subarachnoid hemorrhage
metabolic crises
nerve regeneration
hypoxic-ischemic brain damage
ginsenoside Rg1
neural stem cells
cell transplantation
cell differentiation
cognition
nerve reconstruction
neural regeneration
nerve regeneration
brain injury
neuroimaging
functional magnetic resonance imaging
regional homogeneity
apoplexy
subacute
ischemia
participants
healthy
volunteers
brain activity
NSFC grants
neural regeneration
nerve regeneration
brain injury
neuroprotection
cerebral ischemia/reperfusion injury
lateral intracerebroventricular injection
Apelin-13
nerve apoptosis
Bcl-2
caspase-3
NSFC grants
neural regeneration
nerve regeneration
fractalkine
CX3 chemokine receptor 1
neuronal maturation
dendrites
doublecortin
synaptic maturation
newborn neurons
neural regeneration
nerve regeneration
neurodegenerative diseases
Alzheimer′s disease
transgenic animal models
mice
epimedium herb
milkvetch root
kudzuvine root
divalent metal transporter 1
ferroportin 1
neural regeneration
nerve regeneration
microRNA-124
neurogenesis
neuronal survival
Huntington′s disease
SRY-related HMG box transcription factor 9
brain-derived neurotrophic factor
peroxisome proliferator-activated receptor gamma coactivator 1-alpha
mutant huntingtin
nerve regeneration
Ras/Raf/Erk1/2 signaling pathway
spinal cord injury
apoptosis
repair
regulation
inhibition
neural regeneration
nerve regeneration
neurogenic bladder
bibliometric analysis
Web of Science database
visualization analysis
CiteSpace III
citation analysis
neural regeneration
nerve regeneration
sciatic nerve injury
autologous nerve grafting
epineurial suturing
three-dimensional finite element models
load
stress
displacement
neural regeneration
nerve regeneration
brain injury
facial palsy
Bell′s palsy
comparison
methodological quality
therapy
fixed effect model
acupuncture
incomplete recovery
randomized controlled trials
electroacupuncture
NSFC grants
neural regeneration
nerve regeneration
peripheral nerve injury
thalidomide
ankylosing spondylitis
adverse reactions
peripheral neuropathy
treatment
dose
treatment time
age
sex
neural regeneration
Neurology. Diseases of the nervous system
RC346-429
prospective study
A Study of Three Linker Peptides' Cleavage Efficiency at The Post-translational Level
期刊论文
OAI收割
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2014, 卷号: 41, 期号: 6, 页码: 558-566
作者:
Li, HY
;
Zhou, ZM
;
Pan, Q
;
Yang, DM
;
Gu, JF
收藏
  |  
浏览/下载:402/0
  |  
提交时间:2015/07/22
linker peptide
IETD
EEED
F2A
caspase activity
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells
期刊论文
OAI收割
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:
Zeng, Guang-Zhi
;
Fan, Jun-Ting
;
Xu, Jun-Ju
;
Li, Yan
;
Tan, Ning-Hua
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2015/05/14
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)
one of the major components isolated from the traditional
Chinese medicine Rubia yunnanensis
exhibited inhibitory activity on the proliferation of several
human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay
and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle
arrest in human cervical carcinoma HeLa cells. Further
MTA was found to induce apoptosis of HeLa cells
through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and
release of cytochrome c into the cytosol
which caused the cleavage of caspase and poly(ADP-ribose)
polymerase and finally triggered the apoptosis. Furthermore
the p53/p21/Cdc2-cyclin B1 signaling was
found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of
cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused
the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of
R. yunnanensis
a folk anti-cancer herb used in Yunnan
China.
beta-D-Glucosyl-(1-4)-alpha-L-thevetosides of 17 beta-digitoxigenin from seeds of Cerbera manghas L. induces apoptosis in human hepatocellular carcinoma HepG2 cells
期刊论文
OAI收割
EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY, 2012, 卷号: 64, 期号: 5, 页码: 403-410
作者:
Feng, Bo
;
Guo, Yue-Wei
;
Huang, Cai-Guo
;
Li, Liang
;
Jiao, Bing-Hua
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2019/01/08
beta-D-Glucosyl-(1-4)-alpha-L-thevetosides of 17 beta-digitoxigenin (GHSC-73)
HepG2
Apoptosis-inducing factor (AIF)
Mitochondrial membrane potential (Delta psi(m))
Caspase-3
Apoptosis