中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [101]
西北高原生物研究所 [48]
昆明植物研究所 [41]
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期刊论文 [388]
学位论文 [14]
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2023 [5]
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Cell Biolo... [9]
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A novel pterostilbene compound DCZ0825 induces macrophage M1 differentiation and Th1 polarization to exert anti-myeloma and immunomodulatory
期刊论文
OAI收割
INTERNATIONAL IMMUNOPHARMACOLOGY, 2024, 卷号: 127, 页码: 14
作者:
Zhang, Hui
;
Hu, Ke
;
Lu, Yumeng
;
Xu, Zhijian
;
Chen, Gege
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/03/25
Multiple myeloma
M1 macrophages
Th1 cells
Immunomodulatory
Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 15
作者:
Mei, Lianghe
;
Xu, Lansong
;
Wu, Sanan
;
Wang, Yafang
;
Xu, Chao
  |  
收藏
  |  
浏览/下载:39/0
  |  
提交时间:2023/10/17
Betulinic acid
ROR & gamma
Target identification
Rationale structure optimization
Anti-tumor effects
antagonists
CD71-mediated liposomal arsenic-nickel complex combined with all-trans retinoic acid for the efficacy of acute promyelocytic leukemia
期刊论文
OAI收割
ASIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 18, 期号: 4, 页码: 16
作者:
Liu, Xiao
;
Zhang, Lili
;
Yang, Yueying
;
Yin, Weiwei
;
Liu, Yunhu
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Transferrin
Arsenic trioxide
Acute promyelocytic leukemia
Liposome
All-trans retinoic acid
Alantolactone induces concurrent apoptosis and GSDME-dependent pyroptosis of anaplastic thyroid cancer through ROS mitochondria-dependent caspase pathway
期刊论文
OAI收割
PHYTOMEDICINE, 2023, 卷号: 108
作者:
Hu, Yiqun
;
Wen, Qingliang
;
Cai, Yefeng
;
Liu, Yunye
;
Ma, Wenli
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/12/23
Alantolactone
Anaplastic thyroid cancer
ROS
Pyroptosis
Apoptosis
A novel alkaloid compound, DCZ0358, exerts significant antitumor activity in bortezomib-resistant multiple myeloma cells through inhibition of JAK2/STAT3 pathway
期刊论文
OAI收割
ACTA BIOCHIMICA ET BIOPHYSICA SINICA, 2023, 卷号: 55, 期号: 2, 页码: 215
作者:
Zhang Bibo
;
Li Bo
;
Xie Yongsheng
;
Chang Shuaikang
;
Xu Zhijian
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/07/18
DCZ0358
apoptosis
cell cycle arrest
multiple myeloma
JAK2/STAT3 pathway
Discovery of HCD3514 as a potent EGFR inhibitor against C797S mutation in vitro and in vivo
期刊论文
OAI收割
JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 1, 页码: 152-162
作者:
Lai, Mengzhen
;
Zhang, Tao
;
Chen, Hao
;
Song, Peiran
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2023/04/10
fourth-generation EGFR inhibitor
EGFRC797S mutation
NSCLC
drug resistance
small molecular inhibitor
Toxicological effects of tris(1,3-dichloro-2-propyl) phosphate in oyster Crassostrea gigas using proteomic and phosphoproteomic analyses
期刊论文
OAI收割
JOURNAL OF HAZARDOUS MATERIALS, 2022, 卷号: 434, 页码: 12
作者:
Yin, Chengcheng
;
Sun, Zuodeng
;
Ji, Chenglong
;
Li, Fei
;
Wu, Huifeng
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/07/26
Tris(1
3-dichloro-2-propyl) phosphate
Crassostrea gigas
Proteomics
Phosphoproteomics
Environmentally relevant concentrations of benzophenones triggered DNA damage and apoptosis in male Chinese rare minnows (Gobiocypris rarus)
期刊论文
OAI收割
ENVIRONMENT INTERNATIONAL, 2022, 卷号: 164, 期号: 0, 页码: 107260
作者:
Yan, Saihong
;
Wang, Jun
;
Zheng, Ziting
;
Ji, Fenfen
;
Yan, Liang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2022/11/09
ORGANIC UV-FILTERS
WASTE-WATER TREATMENT
POLYCYCLIC AROMATIC-HYDROCARBONS
CELL-DEATH
PRODUCTS
TOXICITY
EXPOSURE
PHOTOGENOTOXICITY
GENOTOXICITY
BIOMARKERS
GSDMEa-mediated pyroptosis is bi-directionally regulated by caspase and required for effective bacterial clearance in teleost
期刊论文
OAI收割
CELL DEATH & DISEASE, 2022, 卷号: 13, 期号: 5, 页码: 13
作者:
Xu, Hang
;
Jiang, Shuai
;
Yu, Chao
;
Yuan, Zihao
;
Sun, Li
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/07/18
Toxicological effects of acute prothioconazole and prothioconazole-desthio administration on liver in male Chinese lizards (Eremias argus)
期刊论文
OAI收割
CHEMOSPHERE, 2022, 卷号: 291, 期号: 0, 页码: 132825
作者:
Xie, Yun
;
Chang, Jing
;
Pan, Yifan
;
Hao, Weiyu
;
Li, Jianzhong
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2022/11/09
OXIDATIVE STRESS
TISSUE DISTRIBUTION
HEPATOTOXICITY
TOXICOKINETICS
METABOLISM
EXPRESSION
APOPTOSIS
DEATH
PART
MICE