中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [4]
长春光学精密机械与物... [2]
上海神经科学研究所 [2]
生态环境研究中心 [2]
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数学与系统科学研究院 [1]
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OAI收割 [17]
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期刊论文 [11]
学位论文 [3]
会议论文 [2]
SCI/SSCI论文 [1]
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2023 [2]
2022 [3]
2020 [1]
2018 [1]
2015 [2]
2013 [1]
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Design, Synthesis and Bioactivity of [3.3.3]Propellane-Based Voltage-Gated Calcium Channel alpha 2 delta Subunit Ligands
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2023, 卷号: 43, 期号: 6, 页码: 2226-2238
作者:
He Jinyan
;
Tian Fuyun
;
Wu Qingqing
;
Zheng Yueming
;
Chen Yuting
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2023/10/17
propellane
voltage-gated calcium channel
alpha 2 delta subunit
synthesis
bioactivity
structure-activity relationship
Structurally modified Cyclovirobuxine-D Buxus alkaloids as effective analgesic agents through Cav3.2 T-Type calcium channel inhibition
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 135, 页码: 106493
作者:
Munikishore,Rachakunta
;
Liu,Rui
;
Zhang,Shuqun
;
Zhao,Qin-Shi
;
Nian,Yin
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/07/22
Buxus alkaloid
Structural modification
T -type calcium channel
Analgesic activity
Docking analysis
Structure -activity relationship study
BUXOZINE-C
SEMPERVIRENS
RING
CONSTITUTION
Study on structure-activity relationship (SAR) of simplified mirogabalin derivatives as voltage-gated calcium channel alpha 2 delta ligands for the treatment of chronic neuropathic pain
期刊论文
OAI收割
MEDICINAL CHEMISTRY RESEARCH, 2022, 页码: 26
作者:
Zhang, Yuanwen
;
Zheng, Yueming
;
Wu, Qingqing
;
Tian, Fuyun
;
Ma, Chuanjun
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2023/04/10
Voltage-gated calcium channel
alpha 2 delta subunit
gamma-aminobutyric acid
Mirogabalin
Neuropathic pain
Structure-activity relationship
Covariance-Based Joint Device Activity and Delay Detection in Asynchronous mMTC
期刊论文
OAI收割
IEEE SIGNAL PROCESSING LETTERS, 2022, 卷号: 29, 页码: 538-542
作者:
Wang, Zhaorui
;
Liu, Ya-Feng
;
Liu, Liang
  |  
收藏
  |  
浏览/下载:66/0
  |  
提交时间:2022/04/02
Delays
Channel estimation
Signal processing algorithms
Synchronization
Protocols
Performance evaluation
Optimization
Asynchronous mMTC
coordinate descent
joint activity and delay detection
random access
Review of Voltage-gated Calcium Channel alpha 2 delta Subunit Ligands for the Treatment of Chronic Neuropathic Pain and Insight into Structure-activity Relationship (SAR) by Pharmacophore Modeling
期刊论文
OAI收割
CURRENT MEDICINAL CHEMISTRY, 2022, 卷号: 29, 期号: 30, 页码: 5097-5112
作者:
Chen, Yuting
;
Wu, Qingqing
;
Jin, Zhengsheng
;
Qin, Yanlan
;
Meng, Fancui
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2022/11/11
Voltage-gated calcium channel
alpha 2 delta subunit
neuropathic pain
structure-activity relationship (SAR)
pharmacophore modeling
gabapentinoids
Discovery of aryl sulfonamide-selective Nav1.7 inhibitors with a highly hydrophobic ethanoanthracene core
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 293-302
作者:
Wang, Jin-tao
;
Zheng, Yue-ming
;
Chen, Yue-ting
;
Gu, Min
;
Gao, Zhao-bing
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2020/07/01
Nav1
7 sodium channel
aryl sulfonamide
maprotiline
compound 10o
electrophysiology
acetic acid-induced visceral pain
analgesic activity
多肽毒素AK34的结构功能研究
学位论文
OAI收割
北京: 中国科学院大学, 2018
作者:
王鑫
  |  
收藏
  |  
浏览/下载:68/0
  |  
提交时间:2019/09/27
间脚蜈蚣
Ak34
Trpv1通道
生物学活性
Centipede
Ak34
Trpv1 Channel
Biological Activity
Silver nanoparticle exposure induces rat motor dysfunction through decrease in expression of calcium channel protein in cerebellum
期刊论文
OAI收割
TOXICOLOGY LETTERS, 2015, 卷号: 237, 期号: 2, 页码: 112-120
作者:
Yin, Nuoya
;
Zhang, Yang
;
Yun, Zhaojun
;
Liu, Qian
;
Qu, Guangbo
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2016/03/10
Silver nanoparticles
Neurotoxicity
Motor coordination dysfunction
Locomotor activity impairment
Calcium channel protein
面向窄带通信信道的语音质量增强问题研究
学位论文
OAI收割
工学博士, 中国科学院自动化研究所: 中国科学院大学, 2015
作者:
刘斌
收藏
  |  
浏览/下载:107/0
  |  
提交时间:2015/09/02
语音端点检测
单通道语音增强
极低速率语音编码
语音带宽扩展
深层神经网络
speech activity detection
single channel speech enhancement
speech coding at very low bit rate
speech bandwidth extension
deep neural network
构筑根孔湿地中物质迁移转化规律及其梯度净化效应
学位论文
OAI收割
硕士, 北京: 中国科学院研究生院, 2013
王宇
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2014/09/15
构筑根孔湿地
梯度效应
热区
迁移转化
酶活性
constructed root channel wetland
gradient effect
hotspots
transfer and transformation
enzyme activity