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中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [62]
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期刊论文 [296]
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Covalent sortase A inhibitor, α, β-unsaturated aldehydes, prevents Staphylococcus aureus infection
期刊论文
OAI收割
MICROBIAL PATHOGENESIS, 2025, 卷号: 204, 页码: 12
作者:
Wang, Jianchao
;
He, Yuan
;
Chu, Chenliang
;
Wu, Ziqi
;
Zhang, Ting
|
收藏
|
浏览/下载:0/0
|
提交时间:2025/06/23
Sortase A
Covalent inhibitor
alpha
beta-unsaturated aldehydes
Anti-virulence therapy
Staphylococcus aureus
Proteome-Wide Data Guides the Discovery of Lysine-Targeting Covalent Inhibitors Using DNA-Encoded Chemical Libraries
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 14
作者:
Wu, Xinyuan
;
Li, Shunyao
;
Liang, Ting
;
Yu, Qing
;
Zhang, Yiwei
|
收藏
|
浏览/下载:0/0
|
提交时间:2025/06/23
Activity-based protein profiling data
Covalent DNA-encoded chemical library
Covalent ligand selection
Lysine-targeting covalent inhibitors
Dynamic Cap-Mediated Substrate Access and Potent Inhibitor Design of Monkeypox Virus I7L Protease
期刊论文
OAI收割
ADVANCED SCIENCE, 2025, 页码: 13
作者:
Su, Haixia
;
Wu, Guoqing
;
Xiong, Muya
;
Wang, Yuhang
;
Cao, Junyuan
|
收藏
|
浏览/下载:2/0
|
提交时间:2025/05/27
covalent inhibitors
I7L protease
monkeypox virus
protein structures
substrate proteolysis
Discovery of Covalent and Cell-Active ALKBH5 Inhibitors with Potent Antileukemia Effects
In Vivo
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 9
作者:
Wu, Hengbo
;
Lai, Gan-Qiang
;
Cheng, Ruixiang
;
Huang, Hui
;
Wang, Ju
|
收藏
|
浏览/下载:1/0
|
提交时间:2025/04/24
RNA epigenetics
N
(6)-methyladenosine
ALKBH5
covalent inhibitor
antileukemia
Discovery of novel covalent stabilizers for p53 Y220C using structure-based drug discovery methods
期刊论文
OAI收割
MOLECULAR DIVERSITY, 2025, 页码: 14
作者:
Wen, Yiming
;
Xu, Peijia
;
Chen, Yijie
;
Meng, Jingyi
;
Zheng, Mingyue
|
收藏
|
浏览/下载:13/0
|
提交时间:2025/04/01
p53 Y220C
Covalent stabilizer
Virtual screening
Molecular dynamics
DNA binding
Structure-activity relationship
Cancer therapy
In vitro
and
In vivo
Drug Metabolism Analysis of BPI-460372-A Covalent TEAD1/3/4 Inhibitor
期刊论文
OAI收割
CURRENT DRUG METABOLISM, 2025, 页码: 15
作者:
Liu, Xiaoyun
;
Zhong, Dafang
;
Tang, Chongzhuang
;
Xu, Xiaofeng
;
Lan, Hong
|
收藏
|
浏览/下载:0/0
|
提交时间:2025/04/24
Hippo signaling pathway
TEAD inhibitor
covalent inhibitor
BPI-460372
UHPLC-Orbitrap-HRMS
cysteine
S
-conjugate
beta
-lyase.
Identifying a non-conserved site for achieving allosteric covalent inhibition of CECR2
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2025, 页码: 16
作者:
Tang, Cai-ling
;
Li, Yuan-qing
;
Du, Xi-kun
;
Fang, Xiao-xia
;
Guang, Yi-man
|
收藏
|
浏览/下载:15/0
|
提交时间:2025/04/01
dynamics simulation
CECR2
covalent inhibitor
allosteric effect
Design and development of a series of 4-(piperazin-1-yl)pyrimidines as irreversible menin inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 280, 页码: 20
作者:
Luo, Menglan
;
Ye, Yunfei
;
Tang, Lu
;
Kan, Weijuan
;
Chen, Lin
|
收藏
|
浏览/下载:13/0
|
提交时间:2024/11/26
Menin
Covalent inhibitor
Antitumor
Degradation
Photocatalytic overall water splitting Z-schemes for hydrogen production with the X@CTF-0/
β
-Sb (X = S, Se) heterostructures
期刊论文
OAI收割
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS, 2024, 卷号: 703, 页码: 135437
作者:
Sun, Qing-Guo
;
Yang, Chuan-Lu
;
Li, Xiaohu
;
Liu, Yuliang
;
Zhao, Wenkai
|
收藏
|
浏览/下载:1/0
|
提交时间:2024/11/27
Covalent triazine-based frameworks
Z -scheme
Solar-to-hydrogen
Heterostructures
Nonadiabatic molecular dynamics
Synergistic immune augmentation enabled by covalently conjugating TLR4 and NOD2 agonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2024, 卷号: 278, 页码: 15
作者:
Ding, Dong
;
Gao, Runing
;
Lei, Yujuan
;
Liu, Jianing
;
Zhou, Chengkai
|
收藏
|
浏览/下载:14/0
|
提交时间:2024/10/21
TLR4 agonist
NOD2 agonist
Adjuvant
Covalent conjugation
Subunit vaccine
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