机构

• 上海药物研究所 [15]
• 广州地球化学研究所 [3]
• 合肥物质科学研究院 [1]

采集方式

• OAI收割 [19]

内容类型

• 期刊论文 [19]

发表日期

• 2025 [6]
• 2024 [5]
• 2023 [2]
• 2022 [3]
• 2021 [2]
• 2019 [1]
• 更多

学科主题

筛选

浏览/检索结果: 共19条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择发表日期升序发表日期降序题名升序题名降序提交时间升序提交时间降序作者升序作者降序 Rational engineering of degradation tail-driven CELMoD-antibody conjugates for precision malignancy therapy 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 12, 页码: 6510-6528 作者:  Guo, Yu;  Song, Yi;  Wang, Hanlin;  Lu, Yang;  Zhang, Jingyu   |  收藏  |  浏览/下载：4/0  |  提交时间：2026/01/29 Degrader-antibody conjugate  Antibody-drug conjugate  Cereblon E3 ligase modulator  Immunomodulatory drug  Molecular glue  Targeted protein degradation  Multiple myeloma  Hematologic malignancy   Targeting p53 activation: Recent therapeutic advances in cancer and diabetic macular edema 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 297, 页码: 20 作者:  Wang, Zhiyi;  Zhang, Shijie;  Irakoze, Loica Melita;  Zhao, Yujun   |  收藏  |  浏览/下载：2/0  |  提交时间：2025/12/04 p53  MDM2  Protein-protein interaction  Mutant p53  Gene therapy  PROTAC  Degrader   Discovery of indole derivatives as STING degraders 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2025, 卷号: 294, 页码: 21 作者:  An, Yuxiang;  Zhang, Yan;  Luo, Xin;  Lan, Yaohan   |  收藏  |  浏览/下载：19/0  |  提交时间：2025/08/20 Autoimmune diseases  Degrader  Inflammatory  PROTAC  STING   First ATG101-recruiting small molecule degrader for selective CDK9 degradation via autophagy-lysosome pathway 期刊论文  OAI收割 ACTA PHARMACEUTICA SINICA B, 2025, 卷号: 15, 期号: 5, 页码: 2612-2624 作者:  Zhong, Ye;  Xu, Jing;  Cao, Huiying;  Gao, Jie;  Ding, Shaoyue   |  收藏  |  浏览/下载：49/0  |  提交时间：2025/07/25 Protein degradation  Hydrophobic tags  ATG101  Autophagy-lysosome pathway  CDK9  Cyclin T1  Degrader  Antitumor   Cross-Linking Profiling of Molecular Glue Degrader-Induced E3 Ligase Interactome to Expand Target Space 期刊论文  OAI收割 ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2025, 页码: 13 作者:  Xu, Yali;  Zhao, Wensi;  Nie, Hui-Jun;  Wang, Jiamin;  Fu, Jingjing   |  收藏  |  浏览/下载：57/0  |  提交时间：2025/05/27 Chemoproteomics  Genetic code expansion  Molecular glue degrader  Photo-crosslinking  Targeted protein degradation   Recent advances in targeted degradation in the RAS pathway 期刊论文  OAI收割 FUTURE MEDICINAL CHEMISTRY, 2025, 卷号: 17, 期号: 6, 页码: 693-708 作者:  Ge, Zhiming;  Fan, Zisheng;  He, Wei;  Zhou, Guizhen;  Zhou, Yidi   |  收藏  |  浏览/下载：34/0  |  提交时间：2025/04/24 RAS  cancer  mutation  degrader  PROTAC   Discovery of a Potent, selective and orally bioavailable CDK9 degrader for targeting transcription regulation in Triple-Negative breast cancer 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2024, 卷号: 153, 页码: 16 作者:  Nie, Hui-Jun;  Li, Ben-Fu;  Sun, Jingya;  Yuan, Yali;  Zhang, Zhi-Gao   |  收藏  |  浏览/下载：77/0  |  提交时间：2024/11/26 Triple-negative breast cancer  Targeting transcription regulation  Orally bioavailable degrader  PROTAC  Cyclin-dependent Kinase 9   Discovery of KW0113 as a First and Effective PROTAC Degrader of DNMT1 Protein 期刊论文  OAI收割 CHEMMEDCHEM, 2024, 页码: 16 作者:  Wang, Huihui;  Wang, Zhaoliang;  Hu, Linghao;  Yang, Bingjie;  Zong, Liangyi   |  收藏  |  浏览/下载：64/0  |  提交时间：2024/12/16 Degrader  DNMT1  DNA methylation  PROTAC   SIP-metagenomics reveals key drivers of rhizospheric Benzo[a]pyrene bioremediation via bioaugmentation with indigenous soil microbes☆ 期刊论文  OAI收割 ENVIRONMENTAL POLLUTION, 2024, 卷号: 360, 页码: 12 作者:  Zhao, Xuan;  Cheng, Xianghui;  Cai, Xixi;  Wang, Shuang;  Li, Jibing   |  收藏  |  浏览/下载：79/0  |  提交时间：2024/09/13 Stable isotope probing (SIP)  Bioaugmentation  Rhizoremediation  benzo[a]pyrene degrader  Metagenomic  Indigenous soil microbes   Targeting EGFR with molecular degraders as a promising strategy to overcome resistance to EGFR inhibitors 期刊论文  OAI收割 FUTURE MEDICINAL CHEMISTRY, 2024, 页码: 22 作者:  Wang, Qiangfeng;  Zhu, Yumeng;  Pei, Junping   |  收藏  |  浏览/下载：77/0  |  提交时间：2024/10/21 cancer  degrader  EGFR  lysosome-based degradation  PROTAC  resistance