中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [5]
福建物质结构研究所 [1]
合肥物质科学研究院 [1]
西安光学精密机械研究... [1]
采集方式
OAI收割 [8]
内容类型
期刊论文 [8]
发表日期
2024 [1]
2019 [1]
2016 [1]
2013 [1]
2011 [1]
2009 [1]
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学科主题
Biochemist... [1]
Biophysics [1]
Biotechnol... [1]
Mathematic... [1]
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Studying the Effects and Competitive Mechanisms of YOYO-1 on the Binding Characteristics of DOX and DNA Molecules Based on Surface-Enhanced Raman Spectroscopy and Molecular Docking Techniques
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 卷号: 25, 期号: 7
作者:
Li, Yanjie
;
Li, Zhiwei
;
Yun, Penglun
;
Sun, Dan
;
Niu, Yong
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2024/07/18
SERS
molecular docking method
drug molecule
binding site
competitive mechanism
The Structure of MT189-Tubulin Complex Provides Insights into Drug Design
期刊论文
OAI收割
LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 卷号: 16, 期号: 9, 页码: 1069-1073
作者:
Li, Zhongping
;
Ma, Lingling
;
Wu, Chengyong
;
Meng, Tao
;
Ma, Lanping
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2020/07/01
Crystal structure
tubulin
colchicine binding site
inhibitor
MT189
drug design
Drug repurposing to target Ebola virus replication and virulence using structural systems pharmacology
期刊论文
OAI收割
BMC BIOINFORMATICS, 2016, 卷号: 17, 期号: 无, 页码: 1-12
作者:
Zhao, Zheng
;
Martin, Che
;
Fan, Raymond
;
Bourne, Philip E.
;
Xie, Lei
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2017/10/30
Drug Repositioning
Infectious Disease
Indinavir
Sinefungin
Binding Site Similarity
Rna-directed Rna Polymerase
Vp24
The gating charge pathway of an epilepsy-associated potassium channel accommodates chemical ligands
期刊论文
OAI收割
CELL RESEARCH, 2013, 卷号: 23, 期号: 9, 页码: 1106-1118
作者:
Li, Ping
;
Chen, Zhuxi
;
Xu, Haiyan
;
Sun, Haifeng
;
Li, Hao
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
voltage-gated potassium channel
gating charge pathway
KCNQ2 activator
binding site
anti-epilepsy drug
sulfatedpolymannuroguluronateinhibitstatinducedslkcelladhesionviaanovelbindingsiteakkrspatialtriad
期刊论文
OAI收割
actapharmacologicasinica, 2011, 卷号: 32, 期号: 5, 页码: 647
作者:
Wu Yanlin
;
Ai Jing
;
Zhao Jingming
;
Xiong Bing
;
Xin Xiaojie
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2020/07/01
HIV-1 TAT
PROTEIN INTERACTIONS
HEPARAN-SULFATE
KAPOSIS-SARCOMA
DRUG CANDIDATE
GROWTH-FACTOR
DOMAIN
OLIGOSACCHARIDES
MULTIPLE
SIZE
sulfated polymannuroguluronate
transactivating factor of the HIV-1 virus (Tat)
binding site
Kaposi's sarcoma
heparin
mutation
HIV-1
A new drug binding subsite on human serum albumin and drug-drug interaction studied by X-ray crystallography
期刊论文
OAI收割
Journal of Structural Biology, 2008, 卷号: 162, 期号: 1, 页码: 40-49
L. L. Zhu
;
F. Yang
;
L. Q. Chen
;
E. J. Meehan and M. D. Huang
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2013/01/22
human serum albumin
3'-azido-3'-deoxythymidine
salicylic acid
drug-albumin interaction
drug-drug interaction
drug binding site
X-ray crystallography
mitochondrial azt metabolism
fatty-acid-binding
reverse-transcriptase
crystal-structure
acetylsalicylic-acid
multidrug-resistance
ligand-binding
sites
competition
plasma