中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [80]
合肥物质科学研究院 [12]
金属研究所 [10]
高能物理研究所 [9]
过程工程研究所 [7]
长春应用化学研究所 [6]
更多
采集方式
OAI收割 [175]
iSwitch采集 [10]
内容类型
期刊论文 [184]
会议论文 [1]
发表日期
2024 [4]
2023 [8]
2022 [7]
2021 [5]
2020 [11]
2019 [15]
更多
学科主题
Pharmacolo... [5]
Chemistry [3]
Oncology [3]
Cell Biolo... [2]
Chemistry,... [2]
Biochemist... [1]
更多
筛选
浏览/检索结果:
共185条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
发表日期升序
发表日期降序
IHCH9033, a novel class I HDAC inhibitor, synergizes with FLT3 inhibitor and rescues quizartinib resistance in FLT3-ITD AML via enhancing DNA damage response
期刊论文
OAI收割
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2025, 卷号: 14, 期号: 1, 页码: 19
作者:
Yao, Mingyue
;
Yan, Wenzhong
;
Wang, Yafang
;
Zhao, Yu
;
Xu, Xiaowei
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2025/04/01
Acute myeloid leukemia
HDAC inhibitor
FLT3-ITD mutation
DNA damage response
Synergistic effect
Drug resistance
Confined copper depletion via a hydrogel platform for reversing dabrafenib/cetuximab resistance in BRAFV600E-mutant V600E-mutant colorectal cancer
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2024, 卷号: 375, 页码: 11
作者:
Wang, Jue
;
Sun, Xiangshi
;
Zhao, Zhiwen
;
Wang, Guanru
;
Wang, Dangge
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/11/05
Colorectal cancer
Copper depletion
Drug resistance
Hydrogel
Nanoparticles
Discovery of a novel BTK inhibitor S-016 and identification of a new strategy for the treatment of lymphomas including BTK inhibitor-resistant lymphomas
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:
Song, Pei-ran
;
Wan, Zhi-peng
;
Huang, Ge-ge
;
Song, Zi-lan
;
Zhang, Tao
  |  
收藏
  |  
浏览/下载:64/0
  |  
提交时间:2024/07/12
diffuse large B-cell lymphoma
BTK inhibitors
drug resistance
BTK C481F
BTK A428D
SYHA1813
Proteomics analysis of histone deacetylase inhibitor-resistant solid tumors reveals resistant signatures and potential drug combinations
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2024, 页码: 11
作者:
Hao, Bing-bing
;
Ma, Ke
;
Xu, Jun-yu
;
Fan, Ru-feng
;
Zhao, Wen-si
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2024/03/25
solid tumor
histone deacetylase inhibitor
vorinostat (SAHA)
drug resistance
proteomics
A retrospective study on the mechanism underlying quick transfer from response to resistance in a repeated recurrent chordoma patient with molecular alterations treated with Palbociclib
期刊论文
OAI收割
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, 2024, 卷号: 150, 期号: 2, 页码: 9
作者:
Zhong, Nanzhe
;
Yu, Dong
;
Yang, Minglei
;
Lu, Xingyi
;
Zhang, Qiangzu
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/05/20
Chordoma
Palbociclib
Genomic features
Drug resistance
Epigenetic-based combination therapy and liposomal codelivery overcomes osimertinib-resistant NSCLC via repolarizing tumor-associated macrophages
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 12
作者:
Lin, Ting-ting
;
Xiong, Wei
;
Chen, Gui-hua
;
He, Yang
;
Long, Li
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2024/01/26
osimertinib resistance
targeted drug delivery
liposomes
panobinostat
tumor-associated macrophage
combination therapy
Targeting ST8SIA6-AS1 counteracts KRAS
G12C
inhibitor resistance through abolishing the reciprocal activation of PLK1/c-Myc signaling
期刊论文
OAI收割
EXPERIMENTAL HEMATOLOGY & ONCOLOGY, 2023, 卷号: 12, 期号: 1, 页码: 22
作者:
Wang, Yafang
;
Yao, Mingyue
;
Li, Cheng
;
Yang, Kexin
;
Qin, Xiaolong
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/01/26
KRAS(G12C)
c-Myc
PLK1
LncRNA
ST8SIA6-AS1
Drug resistance
Identification of [1,2,4]Triazolo[4,3-a]pyrazine PARP1 inhibitors with overcome acquired resistance activities
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 259, 页码: 19
作者:
Wang, Pingyuan
;
Zhu, Wen-Ting
;
Wang, Yajing
;
Song, Shan-Shan
;
Xi, Yong
  |  
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2023/10/17
PARP1 inhibitor
Synthetic lethality
Drug resistance
Anticancer
Structure -activity relationship
Hedgehog pathway orchestrates the interplay of histone modifications and tailors combination epigenetic therapies in breast cancer
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2601-2612
作者:
Wang, Xiaomin
;
Xu, Jun
;
Sun, Yiming
;
Cao, Siyuwei
;
Zeng, Hanlin
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2023/10/17
HDAC inhibitors
Drug resistance
Histone methylation
Histone acetylation
Epigenetic interplay
Hedgehog pathway
ZIC1
LIFR
Combination therapy
Breast cancer
Smart drug delivery systems to overcome drug resistance in cancer immunotherapy
期刊论文
OAI收割
CANCER BIOLOGY & MEDICINE, 2023, 卷号: 20, 期号: 4, 页码: 248-267
作者:
Yi, Wenzhe
;
Yan, Dan
;
Wang, Dangge
;
Li, Yaping
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/10/17
Cancer immunotherapy
drug resistance
smart drug delivery system
immunosuppressive microenvironment
immune cell