中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [4]
合肥物质科学研究院 [3]
采集方式
OAI收割 [7]
内容类型
期刊论文 [7]
发表日期
2022 [7]
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发表日期:2022
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Targeting PI3K alpha overcomes resistance to KRas(G12C) inhibitors mediated by activation of EGFR and/or IGF1R
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 12
作者:
Qi, Wei-liang
;
Li, Hui-yu
;
Wang, Yi
;
Xu, Lan
;
Deng, Jie-ting
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/04/10
AMG510
KRas(G12C)
PI3K
drug resistance
combination therapy
Duplex real-time fluorescent recombinase polymerase amplification for the rapid and sensitive detection of two resistance genes in drug-resistant Staphylococcus aureus
期刊论文
OAI收割
JOURNAL OF MICROBIOLOGICAL METHODS, 2022, 卷号: 202
作者:
Shi, Zhonglin
;
Li, Yanan
;
Hu, Anzhong
;
Cui, Junsheng
;
Shao, Min
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/12/23
Drug -resistant Staphylococcus aureus
ermA
mecA
Recombinase polymerase amplification
Resistance genes
Drug Degradation Caused by mce3R Mutations Confers Contezolid (MRX-I) Resistance in Mycobacterium tuberculosis
期刊论文
OAI收割
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2022, 卷号: 66, 期号: 10, 页码: 11
作者:
Pi, Rui
;
Chen, Xiaomin
;
Meng, Jian
;
Liu, Qingyun
;
Chen, Yiwang
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/11/11
Mycobacterium tuberculosis
drug resistance
contezolid
Mce3R
Rv1936
degradation
drug resistance mechanisms
Discovery of novel heteroaryl alkynes for highly potent KITD816V cells inhibition to treat gastrointestinal stromal tumors
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 10, 页码: 4004-4007
作者:
Xie, Zhicheng
;
Li, Lin
;
Guo, Yihao
;
Zhang, Mi
;
Chen, Taiwen
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/12/13
KITD816V cells
Mutation
Drug resistance
Gastrointestinal stromal tumors
Drug-resistant HER2-positive breast cancer: Molecular mechanisms and overcoming strategies
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13
作者:
Wu, Xiaofan
;
Yang, Hongjian
;
Yu, Xingfei
;
Qin, Jiang-Jiang
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/12/22
HER2
breast cancer
targeted therapy
drug resistance
overcoming strategies
CHMFL-26 is a highly potent irreversible HER2 inhibitor for use in the treatment of HER2-positive and HER2-mutant cancers
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022
作者:
Cao, Jiang-yan
;
Qi, Shuang
;
Wu, Hong
;
Wang, Ao-li
;
Liu, Qing-wang
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2022/03/28
HER2
breast cancers
gastric cancers
irreversible inhibitor
drug resistance
The PROTAC selectively degrading Bcl-x(L) represents a novel Hedgehog pathway inhibitor with capacity of combating resistance to Smoothened inhibitors while bone
期刊论文
OAI收割
THERANOSTICS, 2022, 卷号: 12, 期号: 17, 页码: 7476-7490
作者:
Zhang, Shaoqing
;
Chen, Yue
;
Xu, Zhongli
;
Yang, Jun
;
Sun, Renhong
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/04/10
Hedgehog
Bcl-xL
PROTAC
drug resistance
bone growth