中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [3]
广州地球化学研究所 [1]
采集方式
OAI收割 [4]
内容类型
期刊论文 [4]
发表日期
2025 [2]
2024 [1]
2022 [1]
学科主题
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Guiding precision medicine strategy for intravenous ginsenosides via pharmacokinetic-informed bioinformatic approaches: a study on XueShuanTong
期刊论文
OAI收割
PHYTOMEDICINE, 2025, 卷号: 143, 页码: 18
作者:
Jia, Wei-Wei
;
Tian, Nan-Nan
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2025/08/20
Precision medicine
Physiologically based pharmacokinetic model
Ginsenoside
Albumin-facilitated dissociation
Drug interaction
Drug transporter
Hepatic impairment
Pharmacokinetics and Safety of TPN171 (a PDE5 Inhibitor) in Patients With Mild or Moderate Hepatic Impairment Versus Participants With Normal Hepatic Function: A Phase I Study
期刊论文
OAI收割
CLINICAL PHARMACOLOGY IN DRUG DEVELOPMENT, 2025, 页码: 7
作者:
Zhou, Jing
;
Zhang, Hong
;
Ding, Yanhua
;
Wang, Zhen
;
Wang, Yu
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2025/06/23
hepatic impairment
pharmacokinetics
phosphodiesterase-5 inhibitor
TPN171
Polystyrene microplastics exposure: Disruption of intestinal barrier integrity and hepatic function in infant mice
期刊论文
OAI收割
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2024, 卷号: 288, 页码: 10
作者:
Li, Huan
;
Xu, Shimin
;
Zhou, Feng
;
Liu, Su
;
Zhang, Dong
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2025/04/01
Polystyrene microplastics (PSMPs)
Infant mice
Oral exposure
Intestinal barrier impairment
Hepatic injury
Changes in Disposition of Ezetimibe and Its Active Metabolites Induced by Impaired Hepatic Function: The Influence of Enzyme and Transporter Activities
期刊论文
OAI收割
PHARMACEUTICS, 2022, 卷号: 14, 期号: 12, 页码: 22
作者:
Xie, Ningjie
;
Wang, Hong
;
Qin, Hua
;
Guo, Zitao
;
Xue, Hao
  |  
收藏
  |  
浏览/下载:42/0
  |  
提交时间:2023/04/10
hepatic impairment
ezetimibe
active metabolites
phase II enzymes
transporters
first-pass metabolism
inhibitory bile acids