机构

• 上海药物研究所 [9]
• 大连化学物理研究所 [2]

采集方式

• OAI收割 [10]
• iSwitch采集 [1]

内容类型

• 期刊论文 [11]

发表日期

• 2022 [2]
• 2018 [4]
• 2017 [1]
• 2016 [1]
• 2011 [3]

学科主题

筛选

浏览/检索结果: 共11条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Changes in Disposition of Ezetimibe and Its Active Metabolites Induced by Impaired Hepatic Function: The Influence of Enzyme and Transporter Activities 期刊论文  OAI收割 PHARMACEUTICS, 2022, 卷号: 14, 期号: 12, 页码: 22 作者:  Xie, Ningjie;  Wang, Hong;  Qin, Hua;  Guo, Zitao;  Xue, Hao   |  收藏  |  浏览/下载：20/0  |  提交时间：2023/04/10 hepatic impairment  ezetimibe  active metabolites  phase II enzymes  transporters  first-pass metabolism  inhibitory bile acids   Intestinal Glucuronidation, Prior to Hepatic Glucuronidation, Plays an Important Role in the Low Circulating Levels of Calycosin 期刊论文  OAI收割 SEPARATIONS, 2022, 卷号: 9, 期号: 5, 页码: 15 作者:  Jiang, Haodong;  Liu, Huan;  Hu, Pei;  Chen, Shuoji;  Ye, Yaqing   |  收藏  |  浏览/下载：24/0  |  提交时间：2022/08/16 calycosin  first-pass effect  intestinal glucuronidation  liver distribution  metabolism   A Biomimetic Human Gut-on-a-Chip for Modeling Drug Metabolism in Intestine 期刊论文  OAI收割 ARTIFICIAL ORGANS, 2018, 卷号: 42, 期号: 12, 页码: 1196-1205 作者:  Guo, Yaqiong;  Li, Zhongyu;  Su, Wentao;  Wang, Li;  Zhu, Yujuan   |  收藏  |  浏览/下载：63/0  |  提交时间：2019/06/20 Gut-on-a-chip  Caco-2  Intestinal metabolism  Biomimetic  Drug metabolism   A biomimetic human gut-on-a-chip for modeling drug metabolism in intestine 期刊论文  iSwitch采集 Artificial organs, 2018, 卷号: 42, 期号: 12, 页码: 1196-1205 作者:  Guo, Yaqiong;  Li, Zhongyu;  Su, Wentao;  Wang, Li;  Zhu, Yujuan 收藏  |  浏览/下载：68/0  |  提交时间：2019/05/08 Gut-on-a-chip  Caco-2  Intestinal metabolism  Biomimetic  Drug metabolism   Metabolism, pharmacokinetics, and hepatic disposition of xanthones and saponins on Zhimu treatments for exploratively interpreting the discrepancy between the herbal safety and timosaponin A3-induced hepatotoxicity 期刊论文  OAI收割 Acta pharmacologica Sinica, 2018, 卷号: 39, 期号: 12, 页码: 1923-1934 作者:  Xie, Yang;  Zhou, Xu;  Pei, Hu;  Chen, Ming-Cang;  Sun, Zhao-Lin   |  收藏  |  浏览/下载：91/0  |  提交时间：2019/01/08 metabolismpharmacokineticsandhepaticdispositionofxanthonesandsaponinsonzhimutreatmentsforexplorativelyinterpretingthediscrepancybetweentheherbalsafetyandtimosaponina3inducedhepatotoxicity 期刊论文  OAI收割 actapharmacologicasinica, 2018, 卷号: 39, 期号: 12, 页码: 1923 作者:  Xie Yang;  Zhou Xu;  Pei Hu;  Chen Mingcang;  Sun Zhaolin   |  收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01 B-II  LIVER-INJURY  IN-VITRO  ANEMARRHENA-ASPHODELOIDES  OXIDATIVE STRESS  RAT PLASMA  A-III  MANGIFERIN  NORATHYRIOL  EXTRACT  Zhimu  timosaponin A3  mangiferin  pharmacokinetics  metabolism  hepatotoxicity  antioxidant   Arylacetamide Deacetylase Is Involved in Vicagrel Bioactivation in Humans 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2017, 卷号: 8 作者:  Jiang, Jinfang;  Chen, Xiaoyan;  Zhong, Dafang   |  收藏  |  浏览/下载：32/0  |  提交时间：2019/01/08 arylacetamide deacetylase  vicagrel  clopidogrel  hydrolytic metabolism   Pharmacokinetics of mangiferin and its metabolite-Norathyriol, Part 1: Systemic evaluation of hepatic first-pass effect in vitro and in vivo 期刊论文  OAI收割 BIOFACTORS, 2016, 卷号: 42, 期号: 5, 页码: 533-544 作者:  Tian, Xiaoting;  Gao, Yu;  Xu, Zhou;  Lian, Shan;  Ma, Yuanjie   |  收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 mangiferin  norathyriol  pharmacokinetics  metabolism  liver   An Examination of the Potential Effect of Lipids on the First-Pass Metabolism of the Lipophilic Drug Anethol Trithione 期刊论文  OAI收割 JOURNAL OF PHARMACEUTICAL SCIENCES, 2011, 卷号: 100, 期号: 11, 页码: 5048-5058 作者:  Yu, Hong-Zhen;  Han, Si-Fei;  Li, Ping   |  收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 anethol trithione  medium chain triglycerides  first-pass metabolism  hepatic metabolism  nonlinear pharmacokinetics  dose proportionality  drug metabolizing enzymes  inhibition  formulation  lipids   Absorption and Disposition of Scutellarin in Rats: A Pharmacokinetic Explanation for the High Exposure of Its Isomeric Metabolite 期刊论文  OAI收割 DRUG METABOLISM AND DISPOSITION, 2011, 卷号: 39, 期号: 11, 页码: 2034-2044 作者:  Gao, Chunying;  Chen, Xiaoyan;  Zhong, Dafang   |  收藏  |  浏览/下载：8/0  |  提交时间：2019/01/08