中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [2]
过程工程研究所 [1]
长春应用化学研究所 [1]
采集方式
OAI收割 [4]
内容类型
期刊论文 [4]
发表日期
2019 [1]
2011 [1]
2006 [1]
2003 [1]
学科主题
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Synthesis and Biological Evaluation of Oxopyrido[2,3-d] Pyrimidine-7-ones Derivatives as Covalent L85812/T790M Mutant Selective Epidermal Growth Factor Receptor (EGFR) Inhibitors
期刊论文
OAI收割
LETTERS IN DRUG DESIGN & DISCOVERY, 2019, 卷号: 16, 期号: 8, 页码: 826-834
作者:
Niu, Ao
;
Wang, Yang
;
Yang, Yushe
;
Wei, Jianhai
;
Ding, Jian
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2020/07/01
Non-small cell lung cancer
irreversible inhibitors
EGFR(T79014)( )mutant
anti-tumor
xenograft model
cell proliferation
Vilsmeier Reaction of 3-Aminopropenamides: One-Pot Synthesis of Pyrimidin-4(3H)-ones
期刊论文
OAI收割
journal of organic chemistry, 2011, 卷号: 76, 期号: 8, 页码: 2880-2883
Zhang R
;
Zhang DY
;
Liang YJ
;
Zhou GY
;
Dong DW
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2012/06/11
TYROSINE KINASE INHIBITORS
GROWTH-FACTOR RECEPTOR
HIGHLY SUBSTITUTED PYRIDIN-2(1H)-ONES
BETA-OXO AMIDES
IRREVERSIBLE INHIBITORS
EFFICIENT SYNTHESIS
CARBONYL-COMPOUNDS
HAACK REACTION
DERIVATIVES
FACILE
designsynthesisandantitumorevaluationofanewseriesofnsubstitutedthioureaderivatives
期刊论文
OAI收割
actapharmacologicasinica, 2006, 卷号: 27, 期号: 9, 页码: 1259
作者:
Bing Xiong
;
Xishan Xiong
;
Hong Liu
;
Xiaomin Luo
;
Hualiang Jiang
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2020/07/01
EPIDERMAL-GROWTH-FACTOR
TYROSINE KINASE INHIBITORS
STRUCTURE-BASED DISCOVERY
FACTOR RECEPTOR EGFR
IRREVERSIBLE INHIBITORS
CHEMICAL INHIBITORS
BINDING-SITE
PROTEIN
DOMAIN
DOCKING
N-substituted-thiourea derivatives
anti-tumor
SPAC1
tyrosine kinase inhibitor
virtual screening
3D-QSAR and receptor modeling of tyrosine kinase inhibitors with flexible atom receptor model (FLARM)
期刊论文
OAI收割
JOURNAL OF CHEMICAL INFORMATION AND COMPUTER SCIENCES, 2003, 卷号: 43, 期号: 1, 页码: 298-303
作者:
Peng, T
;
Pei, JF
;
Zhou, JJ
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2013/11/08
growth-factor receptor
binding-site inhibitors
irreversible
inhibitors
pharmacophore model
potent
design
analogs
4-(phenylamino)quinazoline
strategies
cancer