中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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机构
上海药物研究所 [3]
上海生物化学与细胞生... [2]
昆明植物研究所 [1]
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OAI收割 [8]
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期刊论文 [8]
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2021 [1]
2020 [1]
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Oncology [1]
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Development of hedgehog pathway inhibitors by epigenetically targeting GLI through BET bromodomain for the treatment of medulloblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2021, 卷号: 11, 期号: 2, 页码: 488-504
作者:
Liu, Xiaohua
;
Zhang, Yu
;
Li, Yalei
;
Wang, Juan
;
Ding, Huaqian
  |  
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2021/05/24
Medulloblastoma
Hedgehog signaling
pathway
Drug resistance
GLI
BRD4
Medulloblastoma: Molecular understanding, treatment evolution, and new developments
期刊论文
OAI收割
PHARMACOLOGY & THERAPEUTICS, 2020, 卷号: 210, 页码: 13
作者:
Liu, Xiaohua
;
Ding, Chunyong
;
Tan, Wenfu
;
Zhang, Ao
  |  
收藏
  |  
浏览/下载:48/0
  |  
提交时间:2020/07/01
Medulloblastoma
Pediatric brain tumor
Oncogenic driver gene
Hedgehog pathway inhibitor
Smoothened receptor antagonist
Validation of Cadherin HAV6 Peptide in the Transient Modulation of the Blood-Brain Barrier for the Treatment of Brain Tumors
期刊论文
OAI收割
PHARMACEUTICS, 2019, 卷号: 11, 期号: 9, 页码: 16
作者:
Sajesh, Babu, V
;
On, Ngoc H.
;
Omar, Refaat
;
Alrushaid, Samaa
;
Kopec, Brian M.
  |  
收藏
  |  
浏览/下载:93/0
  |  
提交时间:2019/12/20
blood-brain barrier (BBB)
drug delivery
transient modulation
HAV6 cadherin peptide
adenanthin
magnetic resonance imaging (MRI)
medulloblastoma
Integrative analysis of gene expression and DNA methylation through one-class logistic regression machine learning identifies stemness features in medulloblastoma
期刊论文
OAI收割
MOLECULAR ONCOLOGY, 2019, 卷号: 13, 期号: 10, 页码: 2227-2245
作者:
Lian, Hao
;
Han, Yi-Peng
;
Zhao, Yang
;
Li, Qi-Feng
;
Wang, Bao-Cheng
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2020/12/09
connectivity map
machine-learning methods
medulloblastoma
prognostic model
stemness
tumor immune environment
Comprehensive analysis of a microRNA expression profile in pediatric medulloblastoma
期刊论文
OAI收割
MOLECULAR MEDICINE REPORTS, 2017, 卷号: 15, 页码: 4109-4115
作者:
Dai, Junqiang
;
Li, Qiao
;
Bing, Zhitong
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2018/05/31
medulloblastoma
microRNA
microRNA profile
Gene Expression Omnibus database
Ingenuity Pathway Analysis
AT-101 inhibits hedgehog pathway activity and cancer growth
期刊论文
OAI收割
CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2015, 卷号: 76, 期号: 3, 页码: 461-469
作者:
Wang, Juan
;
Peng, Yuanqiu
;
Liu, Yuan
;
Yang, Jun
;
Huang, Ming
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
Hedgehog
AT-101
Gossypol
Medulloblastoma
Smoothened
A statin-regulated microRNA represses human c-Myc expression and function
期刊论文
OAI收割
EMBO MOLECULAR MEDICINE, 2012, 卷号: 4, 期号: 9, 页码: 896-909
作者:
Takwi, AAL
;
Li, Y
;
Buscaglia, LEB
;
Zhang, JW
;
Choudhury, S
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2015/07/22
c-Myc
lovastatin
medulloblastoma
microRNA
miR-33b
Small-molecule inhibitors reveal multiple strategies for Hedgehog pathway blockade
期刊论文
OAI收割
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 卷号: 106, 期号: 33, 页码: 14132-14137
作者:
Hyman, JM
;
Firestone, AJ
;
Heine, VM
;
Zhao, Y
;
Ocasio, CA
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2015/07/22
antagonist
cancer
Gli
medulloblastoma