中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [5]
大连化学物理研究所 [2]
昆明植物研究所 [2]
地理科学与资源研究所 [1]
武汉物理与数学研究所 [1]
生态环境研究中心 [1]
更多
采集方式
OAI收割 [12]
内容类型
期刊论文 [11]
SCI/SSCI论文 [1]
发表日期
2022 [1]
2019 [4]
2017 [1]
2015 [1]
2014 [3]
2009 [1]
更多
学科主题
Chemistry [1]
Pharmacolo... [1]
筛选
浏览/检索结果:
共12条,第1-10条
帮助
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
发表日期升序
发表日期降序
Liquorice Extract and 18 beta-Glycyrrhetinic Acid Protect Against Experimental Pyrrolizidine Alkaloid-Induced Hepatotoxicity in Rats Through Inhibiting Cytochrome P450-Mediated Metabolic Activation
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 14
作者:
Wang, Zhangting
;
Ma, Jiang
;
Yao, Sheng
;
He, Yisheng
;
Miu, Kai-Kei
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/06/15
18 beta-glycyrrhetinic acid
pyrrolizidine alkaloid
cytochrome P450
metabolic activation
competitive inhibition
The molecular mechanism of the antagonistic activity of hydroxylated polybrominated biphenyl (OH-BB80) toward thyroid receptor beta
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2019, 卷号: 697, 页码: -
作者:
Zhang, Xiaofang
;
Cui, Shixuan
;
Pan, Liumeng
;
Dong, Wenhua
;
Ma, Mei
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2020/09/10
Hydroxylated brominated biphenyls
Endocrine disrupting effect
Molecular interactions
Metabolic activation
Role of Metabolic Activation in Elemicin-Induced Cellular Toxicity
期刊论文
OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 29, 页码: 8243-8252
作者:
Wang, Yi-Kun
;
Yang, Xiao-Nan
;
Zhu, Xu
;
Xiao, Xue-Rong
;
Yang, Xiu-Wei
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2019/09/10
elemicin
l'-hydroxyelemicin
metabolic activation
cytotoxicity
Metabolic Activation of Myristicin and Its Role in Cellular Toxicity
期刊论文
OAI收割
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 卷号: 67, 期号: 15, 页码: 4328-4336
作者:
Zhu, Xu
;
Wang, Yi-Kun
;
Yang, Xiao-Nan
;
Xiao, Xue-Rong
;
Zhang, Ting
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2019/05/24
myristicin
1 '-hydroxymyristicin
metabolic activation
metabolomics
Structures of AMP-activated protein kinase bound to novel pharmacological activators in phosphorylated, non-phosphorylated, and nucleotide-free states
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 3, 页码: 953-967
作者:
Yan, Yan
;
Zhou, X. Edward
;
Novick, Scott J.
;
Shaw, Simon J.
;
Li, Yingwu
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/07/01
AMP-activated kinase (AMPK)
AMP
hydrogen exchange mass spectrometry
X-ray crystallography
phosphorylation
activation loop phosphorylation
ADaM site
CBS3
R734
R739
metabolic disorder
energy sensor
Dynamic regulation of fatty acid pools for improved production of fatty alcohols in Saccharomyces cerevisiae
期刊论文
OAI收割
Microbial Cell Factories, 2017, 卷号: 16, 期号: 1
作者:
Zhou,Yongjin J.
;
Nielsen,Jens
;
Teixeira,Paulo Gon?alves
;
Ferreira,Raphael
;
Siewers,Verena
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/06/20
Fatty alcohols
Fatty acid activation
FAA1
Dynamic control
Yeast
Metabolic engineering
A Mechanism-Based Model for the Prediction of the Metabolic Sites of Steroids Mediated by Cytochrome P450 3A4
期刊论文
OAI收割
international journal of molecular sciences, 2015, 卷号: 16, 期号: 7, 页码: 14677-14694
作者:
Dai, Zi-Ru
;
Ai, Chun-Zhi
;
Ge, Guang-Bo
;
He, Yu-Qi
;
Wu, Jing-Jing
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2015/11/17
CYP3A4
steroids
metabolic site
mechanism-based prediction
activation energy
Hepatic cytochrome P450s play a major role in monocrotaline-induced renal toxicity in mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2014, 卷号: 35, 期号: 2, 页码: 292-300
作者:
Yao, Jun
;
Li, Cheng-gang
;
Gong, Li-kun
;
Feng, Chen-chen
;
Li, Chun-zhu
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2019/01/08
monocrotaline
pyrrolizidine alkaloid
hepatic cytochrome P450s
ketoconazole
metabolic activation
hepatic toxicity
renal toxicity
Identification of persulfate oxidation products of polycyclic aromatic hydrocarbon during remediation of contaminated soil
SCI/SSCI论文
OAI收割
2014
Liao X. Y.
;
Zhao D.
;
Yan X. L.
;
Huling S. G.
收藏
  |  
浏览/下载:32/0
  |  
提交时间:2014/12/24
Persulfate
Chemical oxidation
Oxy-PAH
Soil remediation
Intermediates
directed chemical-analysis
genotoxic components
metabolic-activation
pahs
degradation
toxicity
ozonation
acenaphthylene
biodegradation
bioremediation
hepaticcytochromep450splayamajorroleinmonocrotalineinducedrenaltoxicityinmice
期刊论文
OAI收割
actapharmacologicasinica, 2014, 卷号: 35, 期号: 2, 页码: 292
作者:
Yao Jun
;
Li Chenggang
;
Gong Likun
;
Feng Chenchen
;
Li Chunzhu
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/07/01
monocrotaline
pyrrolizidine alkaloid
hepatic cytochrome P450s
ketoconazole
metabolic activation
hepatic toxicity
renal toxicity