中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [177]
上海营养与健康研究... [33]
西北高原生物研究所 [31]
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期刊论文 [419]
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Discovery of betulinic acid derivatives as gut-restricted TGR5 agonists: Balancing the potency and physicochemical properties
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2024, 卷号: 144, 页码: 18
作者:
Zhuo, Ning
;
Yun, Ying
;
Zhang, Chenlu
;
Guo, Shimeng
;
Yin, Jianpeng
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/03/25
Type 2 Diabetes
TGR5 agonist
Betulinic acid
Gut-restricted
Gallbladder-filling effects
Kinetophores
Blocking tumor-platelet crosstalk to prevent tumor metastasis via reprograming glycolysis using biomimetic membrane-hybridized liposomes
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2024, 卷号: 366, 页码: 328-341
作者:
Zhu, Jie
;
Wang, Rui
;
Yang, Chenxiao
;
Shao, Xinyue
;
Zhang, Yi
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2024/03/06
Platelet
Circulating tumor cells (CTCs)
Glycolysis
Metastasis
Hybrid-membrane liposome
Quercetin
Shikonin
Unraveling the complex roles of macrophages in obese adipose tissue: an overview
期刊论文
OAI收割
FRONTIERS OF MEDICINE, 2024, 页码: 32
作者:
Peng, Chang
;
Chen, Jun
;
Wu, Rui
;
Jiang, Haowen
;
Li, Jia
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/02/19
obesity
inflammation
adipose tissue macrophages
adipose tissue homeostasis
Combined transcriptome and proteome analysis reveal the key physiological processes in seed germination stimulated by decreased salinity in the seagrass
Zostera marina
L.
期刊论文
OAI收割
BMC PLANT BIOLOGY, 2023, 卷号: 23, 期号: 1, 页码: 21
作者:
Zhang, Yu
;
Yue, Shidong
;
Liu, Mingjie
;
Wang, Xinhua
;
Xu, Shaochun
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2024/04/07
Seagrass
Zostera marina L.
Seed germination
Low-salinity stimulation
Transcriptome and proteome
AMPK role in epilepsy: a promising therapeutic target?
期刊论文
OAI收割
JOURNAL OF NEUROLOGY, 2023, 页码: 24
作者:
Qi, Yingbei
;
Zhang, Yong-mei
;
Gao, Ya-nan
;
Chen, Wen-gang
;
Zhou, Ting
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/01/26
AMPK
Epilepsy
Neuron Modulation
Metabolism
Ion Channels
mTOR
Pharmaco-proteogenomic characterization of liver cancer organoids for precision oncology
期刊论文
OAI收割
SCIENCE TRANSLATIONAL MEDICINE, 2023, 卷号: 15, 期号: 706, 页码: 15
作者:
Ji, Shuyi
;
Feng, Li
;
Fu, Zile
;
Wu, Gaohua
;
Wu, Yingcheng
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/10/17
The development and benefits of metformin in various diseases
期刊论文
OAI收割
FRONTIERS OF MEDICINE, 2023, 页码: 44
作者:
Dong, Ying
;
Qi, Yingbei
;
Jiang, Haowen
;
Mi, Tian
;
Zhang, Yunkai
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/10/17
metformin
metabolism
cancer
aging
neurological disorder
Genome-Wide Identification of Aqp Family Related to Spermatogenesis in Turbot (Scophthalmus maximus)
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 卷号: 24, 期号: 14, 页码: 12
作者:
Wang, Xueying
;
Zhao, Ning
;
Wang, Tao
;
Huang, Jinwei
;
Liu, Qinghua
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/13
turbot
aqps
spermatogenesis
sperm
Structural insights into ligand recognition and activation of the medium-chain fatty acid-sensing receptor GPR84
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 14
作者:
Liu, Heng
;
Zhang, Qing
;
He, Xinheng
;
Jiang, Mengting
;
Wang, Siwei
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/10/17
Discovery of seven-membered ring berberine analogues as highly potent and specific hCES2A inhibitors
期刊论文
OAI收割
CHEMICO-BIOLOGICAL INTERACTIONS, 2023, 卷号: 378, 页码: 11
作者:
Yang, Yun
;
Xiong, Yuan
;
Zhu, Guanghao
;
Sun, Mengru
;
Zou, Kun
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2023/10/17
Human carboxylesterase 2 (hCES2A)
Berberine analogues
Structure -activity relationships (SAR)
Inhibition kinetics
Selectivity