机构

• 上海药物研究所 [34]
• 大连化学物理研究所 [3]
• 西北高原生物研究所 [2]
• 昆明植物研究所 [1]
• 上海有机化学研究所 [1]
• 上海生物化学与细胞生... [1]
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采集方式

• OAI收割 [42]

内容类型

• 期刊论文 [40]
• 会议论文 [2]

发表日期

• 2022 [4]
• 2021 [3]
• 2020 [2]
• 2019 [4]
• 2018 [3]
• 2017 [4]
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学科主题

• 物理化学 [3]
• Applied [1]
• Chemistry [1]
• Medicinal [1]
• Pharmacolo... [1]
• Pharmacolo... [1]
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筛选

浏览/检索结果: 共42条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Comparative Pharmacokinetic Study of Two Pyrrolizidine Alkaloids Lasiocarpine and Heliotrine in Rats 期刊论文  OAI收割 PLANTA MEDICA, 2022, 页码: 9 作者:  Lin, Feifei;  Zhao, Lijuan;  Wang, Yingying;  Ye, Yang;  Liu, Jia   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/11/11 Lasiocarpine  Heliotrine  pyrrolizidine alkaloid  pharmacokinetics   Nrf2-mediated liver protection by 18 beta-glycyrrhetinic acid against pyrrolizidine alkaloid-induced toxicity through PI3K/Akt/GSK3 beta pathway 期刊论文  OAI收割 PHYTOMEDICINE, 2022, 卷号: 102, 页码: 12 作者:  Wang, Zhangting;  Ma, Jiang;  He, Yisheng;  Miu, Kai-Kei;  Yao, Sheng   |  收藏  |  浏览/下载：47/0  |  提交时间：2022/08/30 Pyrrolizidine alkaloids  Herb-induced liver injury  18 beta-glycyrrhetinic acid  Liquorice  Nuclear factor erythroid-2-related factor 2  PI3K/Akt/GSK3 beta   Liquorice Extract and 18 beta-Glycyrrhetinic Acid Protect Against Experimental Pyrrolizidine Alkaloid-Induced Hepatotoxicity in Rats Through Inhibiting Cytochrome P450-Mediated Metabolic Activation 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 14 作者:  Wang, Zhangting;  Ma, Jiang;  Yao, Sheng;  He, Yisheng;  Miu, Kai-Kei   |  收藏  |  浏览/下载：23/0  |  提交时间：2022/06/15 18 beta-glycyrrhetinic acid  pyrrolizidine alkaloid  cytochrome P450  metabolic activation  competitive inhibition   Kupffer cells play a crucial role in monocrotaline-induced liver injury by producing TNF-alpha 期刊论文  OAI收割 TOXICOLOGY, 2022, 卷号: 468, 页码: 9 作者:  Cao, Yuhan;  Liu, Meng;  Wu, Shouyan;  Xu, Junjiu;  Wang, Wenjie   |  收藏  |  浏览/下载：20/0  |  提交时间：2022/06/15 Monocrotaline  Kupffer cells  Necrosis  Hepatotoxicity   Blood Pyrrole-DNA Adducts Define the Early Tumorigenic Risk in Patients with Pyrrolizidine Alkaloid-Induced Liver Injury 期刊论文  OAI收割 ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS, 2021, 卷号: 8, 期号: 7, 页码: 551-557 作者:  He, Yisheng;  Zhang, Wei;  Ma, Jiang;  Xia, Qingsu;  Song, Zijing   |  收藏  |  浏览/下载：21/0  |  提交时间：2021/08/17 Simultaneous determination of monocrotaline and its N-oxide metabolite in rat plasma using LC-MS/MS: Application to a pharmacokinetic study 期刊论文  OAI收割 BIOMEDICAL CHROMATOGRAPHY, 2021, 页码: 7 作者:  Lin, Feifei;  Pan, Anni;  Ye, Yang;  Liu, Jia   |  收藏  |  浏览/下载：51/0  |  提交时间：2021/08/17 LC-MS  MS  monocrotaline  monocrotaline N-oxide  pharmacokinetics   Quantification of Usaramine and its N-Oxide Metabolite in Rat Plasma Using Liquid Chromatography-Tandem Mass Spectrometry 期刊论文  OAI收割 JOURNAL OF ANALYTICAL TOXICOLOGY, 2021, 卷号: 46, 期号: 5, 页码: 512-518 作者:  Lin, Feifei;  Ma, Yan;  Pan, Anni;  Ye, Yang;  Liu, Jia   |  收藏  |  浏览/下载：10/0  |  提交时间：2022/08/16 Clinical application of pyrrole-hemoglobin adducts as a biomarker of pyrrolizidine alkaloid exposure in humans 期刊论文  OAI收割 ARCHIVES OF TOXICOLOGY, 2020, 页码: 7 作者:  Ma, Jiang;  Zhang, Wei;  He, Yisheng;  Zhu, Lin;  Zhang, Chunyuan   |  收藏  |  浏览/下载：23/0  |  提交时间：2020/12/24 Pyrrolizidine alkaloids  Liver injury  Diagnostic biomarkers  Pyrrole-hemoglobin adducts  Pyrrole-plasma protein adducts   Tu-San-Qi (Gynura japonica): the culprit behind pyrrolizidine alkaloid-induced liver injury in China 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2020, 页码: 11 作者:  Zhu, Lin;  Zhang, Chun-yuan;  Li, Dong-ping;  Chen, Hu-biao;  Ma, Jiang   |  收藏  |  浏览/下载：29/0  |  提交时间：2020/12/24 herb-induced liver injury  hepatic sinusoidal obstruction syndrome  pyrrolizidine alkaloids  Tu-San-Qi  Gynura japonica   Intestinal and hepatic biotransformation of pyrrolizidine alkaloid N-oxides to toxic pyrrolizidine alkaloids 期刊论文  OAI收割 ARCHIVES OF TOXICOLOGY, 2019, 卷号: 93, 期号: 8, 页码: 2197-2209 作者:  Yang, Mengbi;  Ma, Jiang;  Ruan, Jianqing;  Ye, Yang;  Fu, Peter Pi-Cheng   |  收藏  |  浏览/下载：7/0  |  提交时间：2020/07/01 Pyrrolizidine alkaloid N-oxides  Pyrrolizidine alkaloids  Pyrrolizidine alkaloid N-oxide toxicity  Biotransformation of pyrrolizidine alkaloid N-oxides  Microbiota biotransformation