机构

• 上海药物研究所 [6]
• 化学研究所 [1]
• 昆明植物研究所 [1]
• 高能物理研究所 [1]
• 长春应用化学研究所 [1]
• 西安光学精密机械研究... [1]
• 更多

采集方式

• OAI收割 [11]

内容类型

• 期刊论文 [11]

发表日期

• 2024 [2]
• 2023 [1]
• 2022 [1]
• 2018 [1]
• 2017 [1]
• 2016 [1]
• 更多

学科主题

• Biochemist... [1]

筛选

浏览/检索结果: 共11条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 A novel approach to exploit Small-Molecule glucagon-like Peptide-1 receptor agonists with high potency 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2024, 卷号: 107, 页码: 19 作者:  Wang, Xiaoyan;  Yun, Ying;  Chen, Lili;  Guo, Shimeng;  Niu, Buying   |  收藏  |  浏览/下载：33/0  |  提交时间：2024/07/12 Diabetes  GLP-1 receptor  Agonist  Structural optimization  Water molecule replacement  Structure activity relationship  Docking simulation   Studying the Effects and Competitive Mechanisms of YOYO-1 on the Binding Characteristics of DOX and DNA Molecules Based on Surface-Enhanced Raman Spectroscopy and Molecular Docking Techniques 期刊论文  OAI收割 INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 卷号: 25, 期号: 7 作者:  Li, Yanjie;  Li, Zhiwei;  Yun, Penglun;  Sun, Dan;  Niu, Yong   |  收藏  |  浏览/下载：22/0  |  提交时间：2024/07/18 SERS  molecular docking method  drug molecule  binding site  competitive mechanism   Isolation and Identification of Herbicidal Active Compounds from Brassica oleracea L. and Exploration of the Binding Sites of Brassicanate A Sulfoxide 期刊论文  OAI收割 PLANTS-BASEL, 2023, 卷号: 12, 期号: 13, 页码: 2576 作者:  Wang,Yu;  Liu,Wanyou;  Dong,Baozhu;  Wang,Dong;  Nian,Yin   |  收藏  |  浏览/下载：17/0  |  提交时间：2024/05/09 Brassica oleracea L  activity guided  allelochemicals  herbicidal activity  molecule docking  AUXIN BIOSYNTHESIS  PHYTOALEXINS  GERMINATION  MUSTARD  GROWTH   Identification of PRMT5 inhibitors with novel scaffold structures through virtual screening and biological evaluations 期刊论文  OAI收割 JOURNAL OF MOLECULAR MODELING, 2022, 卷号: 28, 期号: 7, 页码: 184 作者:  Zhang, Qian;  Zhang, Lun;  Jin, Jia;  Fan, Yaohua;  Wang, Xiaoguang   |  收藏  |  浏览/下载：24/0  |  提交时间：2024/03/21 PRMT5  Small-molecule inhibitors  Virtual screening  Molecular docking  Molecular dynamics simulations   Molecular modelling studies on cinnoline-based BTK inhibitors using docking and structure-based 3D-QSAR 期刊论文  OAI收割 SAR AND QSAR IN ENVIRONMENTAL RESEARCH, 2018, 卷号: 29, 期号: 11, 页码: 847-873 作者:  Li, R.;  Du, Y.;  Shen, J.   |  收藏  |  浏览/下载：49/0  |  提交时间：2019/01/08 BTK inhibitors  B-cell malignancies  molecule docking  3D-QSAR  CoMFA  CoMSIA   Discovery of alkyl bis(oxy)dibenzimidamide derivatives as novel protein arginine methyltransferase 1 (PRMT1) inhibitors 期刊论文  OAI收割 CHEMICAL BIOLOGY & DRUG DESIGN, 2017, 卷号: 90, 期号: 6, 页码: 1260-1270 作者:  Zhang, Wei-yao;  Lu, Wen-chao;  Jiang, Hao;  Lv, Zheng-bing;  Xie, Yi-qian   |  收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08 epigenetics  molecular docking  PRMT1  scaffold hopping  small-molecule inhibitor   Molecular docking for drug discovery and development: a widely used approach but far from perfect 期刊论文  OAI收割 FUTURE MEDICINAL CHEMISTRY, 2016, 卷号: 8, 期号: 14 作者:  Wang, Guimin;  Zhu, Weiliang   |  收藏  |  浏览/下载：26/0  |  提交时间：2019/01/08 covalent binding  free energy  molecular docking  scoring function  solvent molecule  structural flexibility  thermodynamics and kinetics   policresulenanovelns2bns3proteaseinhibitoreffectivelyinhibitsthereplicationofdenv2virusinbhk21cells 期刊论文  OAI收割 actapharmacologicasinica, 2015, 卷号: 36, 期号: 9, 页码: 1126 作者:  Wu Dengwei;  Mao Fei;  Ye Yan;  Li Jian;  Xu Chuanlian   |  收藏  |  浏览/下载：58/0  |  提交时间：2020/07/01 SMALL-MOLECULE INHIBITORS  STRUCTURE-BASED DISCOVERY  DRUG-LIKE MOLECULES  DENGUE VIRUS  SERINE-PROTEASE  NS3 PROTEASE  PEPTIDE INHIBITORS  NS2B-NS3 PROTEASE  ACCURATE DOCKING  IN-VITRO  Dengue virus  antiviral drug  NS2B/NS3 protease  policresulen  molecular docking  molecular modeling   Live-cell single-molecule imaging reveals clathrin and caveolin-1 dependent docking of SMAD4 at the cell membrane 期刊论文  OAI收割 FEBS LETTERS, 2013, 卷号: 587, 期号: 24, 页码: 3912-3920 作者:  Yang, Yong;  Wolfram, Joy;  Shen, Jianliang;  Zhao, Yuliang;  Fang, Xiaohong   |  收藏  |  浏览/下载：97/0  |  提交时间：2019/04/09 Smad4  Membrane Docking  Single-molecule Fluorescence Imaging  Clathrin  Caveolin-1   Rational Drug Design: The Search for Ras Protein Hydrolysis Intermediate Conformation Inhibitors with Both Affinity and Specificity 期刊论文  OAI收割 current pharmaceutical design, 2013, 卷号: 19, 期号: 12, 页码: 2246-2258 Zheng XL; Liu ZJ; Li D; Wang EK; Wang J 收藏  |  浏览/下载：28/0  |  提交时间：2014/04/20 EMPIRICAL SCORING FUNCTIONS  SMALL-MOLECULE INHIBITOR  SELF-ORGANIZING MAP  MARKETED ORAL-DRUGS  LIGAND INTERACTIONS  FLEXIBLE DOCKING  AUTOMATED DOCKING  BINDING-AFFINITY  GENETIC ALGORITHM  COMPOUND COLLECTIONS