中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [49]
长春应用化学研究所 [9]
化学研究所 [6]
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期刊论文 [80]
学位论文 [2]
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A prodrug nanodevice co-delivering docetaxel and ROR1 siRNA for enhanced triple negative breast cancer therapy
期刊论文
OAI收割
ACTA BIOMATERIALIA, 2025, 卷号: 193, 页码: 498-513
作者:
Yin, Lixuan
;
Fu, Zirang
;
Wang, Mengmeng
;
Liu, Bo
;
Sun, Xujie
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2025/04/01
Triple-negative breast cancer
Docetaxel
Prodrug nanoparticle
ROR1 siRNA
pH responsive
Advancements and challenges in immunocytokines: A new arsenal against cancer
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2024, 卷号: 14, 期号: 11, 页码: 4649-4664
作者:
Shi, Wenqiang
;
Liu, Nan
;
Lu, Huili
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2024/12/25
Bifunctional fusion
Combination therapy
Tumor-conditional
Prodrug
PROTAC Prodrug-Integrated Nanosensitizer for Potentiating Radiation Therapy of Cancer
期刊论文
OAI收割
ADVANCED MATERIALS, 2024, 页码: 12
作者:
Zhang, Shunan
;
Lai, Yi
;
Pan, Jiaxing
;
Saeed, Madiha
;
Li, Shiqin
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2024/04/09
active tumor targeting
nanosensitizer
PROTAC prodrug
radiation therapy
tumor microenvironment
A prodrug of the capsid assembly modulator improved druggability and lowing HBsAg and HBeAg for the treatment of chronic hepatitis B
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 8
作者:
Chen, Wuhong
;
Gong, Ying
;
Long, Guozhang
;
Wang, Xinran
;
Yang, Yurong
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/10/17
HBV
Capsid assembly modulators
Prodrug
Hepatitis B surface antigen
Stimuli-activatable PROTACs for precise protein degradation and cancer therapy
期刊论文
OAI收割
SCIENCE BULLETIN, 2023, 卷号: 68, 期号: 10, 页码: 1069-1085
作者:
Gao, Jing
;
Yang, Lei
;
Lei, Shumin
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2023/10/17
PROTAC
Stimuli-activatable prodrug
Precise protein degradation
Nanomedicine
Combinatory therapy
Structure-activity relationship study of a series of nucleoside derivatives bearing sulfonamide scaffold as potent and selective PRMT5 inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 20
作者:
Chen, Yuting
;
Shi, Qiongyu
;
Yang, Hong
;
Li, Jiayi
;
Zhou, Kaixin
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2023/04/10
Epigenetic
PRMT5 inhibitor
Nucleoside derivatives
Structure-activity Relationship Prodrug
In-situ clickable prodrug nanoplatform locally activates T lymphocytes to potentiate cancer immunotherapy
期刊论文
OAI收割
NANO TODAY, 2022, 卷号: 47, 页码: 11
作者:
Hou, Bo
;
Ye, Jiayi
;
Li, Junhao
;
Xu, Zhiai
;
Yu, Haijun
  |  
收藏
  |  
浏览/下载:45/0
  |  
提交时间:2023/04/10
Immune-excluded tumor
Extracellular matrix
In-situ click reaction
Prodrug nanoparticles
Immune resistance
Evaluation of Transdermal Transport and Concurrent Cutaneous Hydrolysis of Timolol Prodrug for the Treatment of Infantile Hemangiomas
期刊论文
OAI收割
PHARMACEUTICS, 2022, 卷号: 14, 期号: 8, 页码: 12
作者:
Chang, Shih-Jen
;
Wang, Huiyuan
;
Chen, Jialin
;
Chen, Qianyi
;
Chang, Lei
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/09/30
infantile hemangioma
timolol maleate
butyryl timolol maleate
prodrug
sequelae
hydrolysis
Targeted delivery and enhanced uptake of chemo-photodynamic nanomedicine for melanoma treatment
期刊论文
OAI收割
ACTA BIOMATERIALIA, 2022, 卷号: 147, 页码: 356-365
作者:
Huang, Xiaobei
;
Mu, Ning
;
Ding, Yuanfu
;
Lam, Hou Wang
;
Yue, Ludan
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/08/22
Photodynamic-chemotherapeutic therapy
Pt(IV) prodrug
Charge -reversal
Targeted drug delivery
Controlled drug release
Bispecific prodrug nanoparticles circumventing multiple immune resistance mechanisms for promoting cancer immunotherapy
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 6, 页码: 2695-2709
作者:
Ye, Jiayi
;
Hou, Bo
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2024/03/21
Immunotherapy
Prodrug nanoparticles
Immune evasion
Immunogenic cell death
Tumor microenvironment