中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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浏览/检索结果: 共8条,第1-8条 帮助

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Emerging insights into heterotrimeric G protein signaling in plants 期刊论文  OAI收割
JOURNAL OF GENETICS AND GENOMICS, 2016, 卷号: 43, 期号: 8, 页码: 495-502
作者:  
Xu Quan;  Zhao Mingzhu;  Wu Kun;  Fu Xiangdong;  Liu Qian
  |  收藏  |  浏览/下载:31/0  |  提交时间:2021/02/02
Complementarity in nutrient foraging strategies of absorptive fine roots and arbuscular mycorrhizal fungi across 14 coexisting subtropical tree species SCI/SSCI论文  OAI收割
2015
作者:  
Liu B. T.;  Li, H. B.;  Zhu, B. A.;  Koide, R. T.;  Eissenstat, D. M.
收藏  |  浏览/下载:48/0  |  提交时间:2015/12/09
Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文  OAI收割
PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299
作者:  
Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua
收藏  |  浏览/下载:51/0  |  提交时间:2015/05/14
2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)  one of the major components isolated from the traditional  Chinese medicine Rubia yunnanensis  exhibited inhibitory activity on the proliferation of several  human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay  and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle  arrest in human cervical carcinoma HeLa cells. Further  MTA was found to induce apoptosis of HeLa cells  through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and  release of cytochrome c into the cytosol  which caused the cleavage of caspase and poly(ADP-ribose)  polymerase and finally triggered the apoptosis. Furthermore  the p53/p21/Cdc2-cyclin B1 signaling was  found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of  cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused  the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of  R. yunnanensis  a folk anti-cancer herb used in Yunnan  China.  
Puerarin prevents high glucose-induced apoptosis of Schwann cells by inhibiting oxidative stress 期刊论文  OAI收割
NEURAL REGENERATION RESEARCH, 2012, 卷号: 7, 期号: 33, 页码: 2583-2591
作者:  
Wu Yingying;  Xue Bing;  Li Xiaojin;  Liu Hongchen
  |  收藏  |  浏览/下载:21/0  |  提交时间:2021/02/02
Blockade of TRPC6 channels induced G2/M phase arrest and suppressed growth in human gastric cancer cells 期刊论文  OAI收割
INTERNATIONAL JOURNAL OF CANCER, 2009, 卷号: 125, 期号: 10, 页码: 2281-2287
作者:  
Wang, Yizheng
收藏  |  浏览/下载:45/0  |  提交时间:2012/07/13
Critical role of TRPC6 channels in VEGF-mediated angiogenesis 期刊论文  OAI收割
CANCER LETTERS, 2009, 卷号: 283, 期号: 1, 页码: 43-51
作者:  
Wang, Yizheng
收藏  |  浏览/下载:50/0  |  提交时间:2012/07/13
Interleukin-2 expression and glioma cell proliferation following Vaccinia vector gene transfection in vivo 期刊论文  OAI收割
NEURAL REGENERATION RESEARCH, 2008, 卷号: 3, 期号: 4, 页码: 415-417
作者:  
Wang Xiaogang;  Wei Xuezhong;  Liu Jiangqiu
  |  收藏  |  浏览/下载:17/0  |  提交时间:2021/02/26
Allelopathic potential of Astragalus adsurgens Pall on the growth of cultured Stelleria chamaejasme L 期刊论文  OAI收割
ALLELOPATHY JOURNAL, 2006, 卷号: 17, 期号: 2, 页码: 255-264
Yu FK; Ma YQ; Wei GH
收藏  |  浏览/下载:30/0  |  提交时间:2012/06/15