机构

• 金属研究所 [7]
• 上海药物研究所 [4]
• 理论物理研究所 [1]
• 上海神经科学研究所 [1]
• 上海营养与健康研究所 [1]

采集方式

• OAI收割 [14]

内容类型

• 期刊论文 [14]

发表日期

• 2020 [2]
• 2018 [1]
• 2017 [2]
• 2015 [1]
• 2012 [1]
• 2011 [2]
• 更多

学科主题

• Biochemist... [1]
• Biophysics [1]
• Computer S... [1]
• Engineerin... [1]
• Genetics &... [1]
• Telecommun... [1]
• 更多

筛选

浏览/检索结果: 共14条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择题名升序题名降序提交时间升序提交时间降序作者升序作者降序发表日期升序发表日期降序 Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels 期刊论文  OAI收割 JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856 作者:  Liu, Wen;  Yin, Ye;  Wang, Meijing;  Fan, Ting;  Zhu, Yuyu   |  收藏  |  浏览/下载：98/0  |  提交时间：2020/12/24 Src homology 2 domain containing tyrosine phosphatase-2 (SHP2)  hepatic steatosis  insulin resistance  caspase-1  interleukin 18 (IL-18)  fatty liver  metabolic disorder  inflammation  cytokine signaling  caspase 1 (CASP1)  tyrosine-protein phosphatase (tyrosine phosphatase)  macrophage   Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide 期刊论文  OAI收割 JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 28, 页码: 9313-9325 作者:  Chang, Rulue;  Zhang, Xin;  Qiao, Anna;  Dai, Antao;  Belousoff, Matthew J.   |  收藏  |  浏览/下载：54/0  |  提交时间：2020/12/24 glucagon receptor  glucagon-like peptide-1 receptor  dual agonist  cryo-electron microscopy  single particle analysis  structure-function  structural biology  peptide 15 (P15)  metabolic disorder  G protein?coupled receptor (GPCR)  glucagon  GLP-1 receptor   Comparing NMR and X-ray protein structure: Lindemann-like parameters and NMR disorder 期刊论文  OAI收割 JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, 2018, 卷号: 36, 期号: 9, 页码: 2331-2341 作者:  Sussman, JL;  Faraggi, E;  Dunker, AK;  Kloczkowski, A   |  收藏  |  浏览/下载：97/0  |  提交时间：2018/12/27 BACKBONE TORSION ANGLES  MAJOR URINARY PROTEIN  INTRINSIC DISORDER  STRUCTURE PREDICTION  SECONDARY STRUCTURE  CRYSTAL-STRUCTURE  DYNAMICS  DIFFRACTION  CRYSTALLOGRAPHY  RECOGNITION   Identify Key Sequence Features to Improve CRISPR sgRNA Efficacy 期刊论文  OAI收割 IEEE ACCESS, 2017, 卷号: 5, 期号: -, 页码: 26582-26590 作者:  Chen, Lei;  Wang, Shaopeng;  Li, Jiarui;  Cai, Yu-Dong;  Zhang, Yu-Hang   |  收藏  |  浏览/下载：17/0  |  提交时间：2020/12/09 CRISPR/Cas9 system  sgRNAs  maximal-relevance-minimal-redundancy  incremental feature selection  protein disorder   Whole-genome sequencing of monozygotic twins discordant for schizophrenia indicates multiple genetic risk factors for schizophrenia 期刊论文  OAI收割 JOURNAL OF GENETICS AND GENOMICS, 2017, 卷号: 44, 期号: 6, 页码: 295-306 作者:  Tang Jinsong;  Fan Yu;  Li Hong;  Xiang Qun   |  收藏  |  浏览/下载：28/0  |  提交时间：2021/02/02 DE-NOVO MUTATIONS  STRUCTURAL VARIANT DISCOVERY  WIDE ASSOCIATION  PSYCHIATRIC-DISORDERS  SYNAPTIC PLASTICITY  BIPOLAR DISORDER  PROTEIN FUNCTION  COMPLEX TRAITS  MESSENGER-RNA  HUMAN-DISEASE  Whole-genome sequencing  Schizophrenia  Monozygotic twin  De novo mutation  Combined effect  Susceptibility   yhhu981anovelcompoundstimulatesfattyacidoxidationviatheactivationofampkandameliorateslipidmetabolismdisorderinobobmice 期刊论文  OAI收割 actapharmacologicasinica, 2015, 卷号: 36, 期号: 3, 页码: 343 作者:  Zeng Hongliang;  Huang Suling;  Xie Fuchun;  Zeng Limin;  Hu Youhong   |  收藏  |  浏览/下载：22/0  |  提交时间：2020/07/01 PROTEIN-KINASE ACTIVATION  RAT SOLEUS MUSCLE  SKELETAL-MUSCLE  INSULIN SENSITIVITY  MALONYL-COA  MITOCHONDRIAL BIOGENESIS  MYOBLAST DIFFERENTIATION  ENERGY-EXPENDITURE  DEFICIENT MICE  GLUCOSE-UPTAKE  yhhu981  fatty acid oxidation  fatty acid synthesis  AMPK  compound C  sirtinol  EX527  STO609  AICAR  metformin  metabolism disorder  C2C12 myotubes  HepG2 cells  ob/ob mice   A case report of Chinese brothers with inherited MECP2-containing duplication: autism and intellectual disability, but not seizures or respiratory infections 期刊论文  OAI收割 BMC MEDICAL GENETICS, 2012, 卷号: 13, 期号: Aug, 页码: -75 Xu, X; Xu, Q; Zhang, Y; Zhang, XD; Cheng, TL; Wu, BB; Ding, YH; Lu, P; Zheng, JJ; Zhang, M; Qiu, ZL; Yu, X 收藏  |  浏览/下载：32/0  |  提交时间：2013/06/04 SEVERE MENTAL-RETARDATION  CREATINE TRANSPORTER DEFICIENCY  CPG-BINDING PROTEIN-2  GENE COPY NUMBER  RETT-SYNDROME  MECP2 GENE  NEUROLOGICAL SYMPTOMS  RECURRENT INFECTIONS  XQ28  DISORDER   Identification of small molecular inhibitors for Ero1p by structure-based virtual screening 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2011, 卷号: 21, 期号: 4, 页码: 1118-1121 作者:  Chu, Yanyan;  Chen, Xianjun;  Yang, Yi;  Tang, Yun   |  收藏  |  浏览/下载：14/0  |  提交时间：2019/01/08 Virtual screening  Ero1p  Disulfide bond  Protein disorder  Oxidoreductase   THE PROPERTIES OF PROTON CONDUCTIVITY ALONG THE HYDROGEN-BONDED MOLECULAR SYSTEMS WITH DAMPING UNDER INFLUENCES OF THERMAL PERTURBATION AND STRUCTURE NONUNIFORMITY 期刊论文  OAI收割 International Journal of Modern Physics B, 2011, 卷号: 25, 期号: 1, 页码: 55-71 P. Xiao-Feng; Y. Jia-Feng; Z. Hong-Juan 收藏  |  浏览/下载：23/0  |  提交时间：2012/04/13 Hydrogen bond  proton transfer  structure nonuniformity  thermal  perturbation  mobility  RungeKutta method  transported bio-energy  protein molecules  improved model  dynamic  properties  solitons  mechanisms  disorder  quantum  motion  ice   Influence of structure disorders and temperatures of systems on the bio-energy transport in protein molecules (II) 期刊论文  OAI收割 Frontiers of Physics in China, 2008, 卷号: 3, 期号: 4, 页码: 457-488 X. F. Pang 收藏  |  浏览/下载：12/0  |  提交时间：2012/04/13 protein molecule  biological energy  soliton stability  structure  disorder  temperature  exciton  Runge-Kutta way  numerical simulation