中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [8]
长春光学精密机械与物... [5]
自动化研究所 [3]
大连化学物理研究所 [2]
昆明植物研究所 [2]
生态环境研究中心 [2]
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OAI收割 [34]
iSwitch采集 [1]
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期刊论文 [26]
会议论文 [7]
学位论文 [2]
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2024 [3]
2023 [4]
2022 [3]
2021 [3]
2020 [1]
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学科主题
Engineerin... [1]
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Ginkgetin Alleviates Inflammation and Senescence by Targeting STING
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 15
作者:
Liu, Yadan
;
Ye, Jialin
;
Fan, Zisheng
;
Wu, Xiaolong
;
Zhang, Yinghui
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/12/16
cGAS-STING signaling
Ginkgetin
senescence
STING inhibitor
target identification
PROTAC derivatization of natural products for target identification and drug discovery: Design of evodiamine-based PROTACs as novel REXO4 degraders
期刊论文
OAI收割
JOURNAL OF ADVANCED RESEARCH, 2024, 卷号: 63, 页码: 219-230
作者:
Chen, Shuqiang
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2024/10/21
PROTAC
Natural products
Target identification
Quantitative proteomics
Antitumor activities
Target Identification and Mechanistic Characterization of Indole Terpenoid Mimics: Proper Spindle Microtubule Assembly Is Essential for Cdh1-Mediated Proteolysis of CENP-A
期刊论文
OAI收割
ADVANCED SCIENCE, 2024, 页码: 14
作者:
Peng, Yan
;
Zhang, Yumeng
;
Fang, Ruan
;
Jiang, Hao
;
Lan, Gongcai
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2024/07/12
Cdh1
CENP-A regulation
colchicine-binding site inhibitor
indole terpenoid
target identification
Discovery, structural optimization, and anti-tumor bioactivity evaluations of betulinic acid derivatives as a new type of ROR & gamma; antagonists
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 15
作者:
Mei, Lianghe
;
Xu, Lansong
;
Wu, Sanan
;
Wang, Yafang
;
Xu, Chao
  |  
收藏
  |  
浏览/下载:60/0
  |  
提交时间:2023/10/17
Betulinic acid
ROR & gamma
Target identification
Rationale structure optimization
Anti-tumor effects
antagonists
Toxicity identification evaluation for hydraulic fracturing flowback and produced water during shale gas exploitation in China: Evidence from tissue residues and gene expression
期刊论文
OAI收割
WATER RESEARCH, 2023, 卷号: 241, 页码: 12
作者:
Wu, Fan
;
Zhou, Zhimin
;
Zhang, Shaoqiong
;
Cheng, Fei
;
Tong, Yujun
  |  
收藏
  |  
浏览/下载:80/0
  |  
提交时间:2024/08/22
Shale gas
Ecological risk from mixtures
Toxicity identification evaluation
Non -target analysis
Organismal uptake
Transcriptomic analysis
ETCM v2.0: An update with comprehensive resource and rich annotations for traditional Chinese medicine
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 6, 页码: 2559-2571
作者:
Zhang, Yanqiong
;
Li, Xin
;
Shi, Yulong
;
Chen, Tong
;
Xu, Zhijian
  |  
收藏
  |  
浏览/下载:57/0
  |  
提交时间:2023/10/17
Traditional Chinese medicine
Database
Target identification
Network visualization
New drug research and development
Molecular mechanism
Quality marker
Drug repurposing
Progressive Context-Aware Graph Feature Learning for Target Re-Identification
期刊论文
OAI收割
IEEE TRANSACTIONS ON MULTIMEDIA, 2023, 卷号: 25, 页码: 1230-1242
作者:
Cao, Min
;
Ding, Cong
;
Chen, Chen
;
Dou, Hao
;
Hu, Xiyuan
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/11/16
Target re-identification
graph convolutional network
feature learning
contextual information
graph feature learning
An Improved YOLOV5 Based on Triplet Attention and Prediction Head Optimization for Marine Organism Detection on Underwater Mobile Platforms
期刊论文
OAI收割
JOURNAL OF MARINE SCIENCE AND ENGINEERING, 2022, 卷号: 10, 期号: 9, 页码: 13
作者:
Li, Yan
;
Bai, Xinying
;
Xia, Chunlei
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/11/07
marine organism
target identification
deep learning
attention mechanism
model optimization
An Improved YOLOV5 Based on Triplet Attention and Prediction Head Optimization for Marine Organism Detection on Underwater Mobile Platforms
期刊论文
OAI收割
JOURNAL OF MARINE SCIENCE AND ENGINEERING, 2022, 卷号: 10, 期号: 9, 页码: 13
作者:
Li, Yan
;
Bai, Xinying
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/11/15
marine organism
target identification
deep learning
attention mechanism
model optimization
Triclosan is the Predominant Antibacterial Compound in Ontario Sewage Sludge
期刊论文
OAI收割
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2022, 期号: 0, 页码: 1-14
作者:
Barrett, Holly
;
Sun, Jianxian
;
Gong, Yufeng
;
Yang, Paul
;
Hao, Chunyan
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/11/09
ANTIBIOTIC-RESISTANCE
DISRUPTING COMPOUNDS
MASS-SPECTROMETRY
WASTE-WATER
IDENTIFICATION
EXTRACTION
TARGET
GENES
CONTAMINANTS
TRICLOCARBAN