中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [9]
金属研究所 [1]
昆明植物研究所 [1]
采集方式
OAI收割 [11]
内容类型
期刊论文 [11]
发表日期
2022 [1]
2021 [1]
2020 [1]
2019 [2]
2014 [1]
2009 [3]
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学科主题
Chemistry [1]
Pharmacolo... [1]
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ASK120067 potently suppresses B-cell or T-cell malignancies in vitro and in vivo by inhibiting BTK and ITK
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2022, 卷号: 13, 页码: 9
作者:
Song, Peiran
;
Bai, Gang
;
Chan, Shingpan
;
Zhang, Tao
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:58/0
  |  
提交时间:2023/04/10
Bruton's tyrosine kinase
interleukin-2-inducible T cell kinase
ASK120067
B-cell lymphoma
T-cell leukemia
Platelet-activating factor acetyl hydrolase IB2 dysregulated cell proliferation in ovarian cancer
期刊论文
OAI收割
CANCER CELL INTERNATIONAL, 2021, 卷号: 21, 期号: 1, 页码: 697
作者:
He,YingYing
;
He,Zhicheng
;
Zhang,Xiaoyu
;
Liu,Shubai
  |  
收藏
  |  
浏览/下载:73/0
  |  
提交时间:2022/04/02
Ovarian cancer
Ester lipid
Tyrosine kinase signaling pathway
Platelet-activating factor
FACTOR-ACETYLHYDROLASE ACTIVITY
LYSOPHOSPHATIDIC ACID
FACTOR RECEPTOR
EMERGING ROLE
EXPRESSION
GROWTH
PAF
MECHANISMS
PAFAH1B3
SUBUNIT
Discovery and biological evaluation of N-(3-(7-((2-methoxy-4-(4-methylpiperazin-1-yl)phenyl)amino)-4-methyl-2-oxo-2H-pyrimido[4,5-d][1,3]oxazin-1(4H)-yl)phenyl)acrylamide as potent Bruton's tyrosine kinase inhibitors
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 卷号: 41, 期号: 3, 页码: 415-422
作者:
Lai, Meng-zhen
;
Song, Pei-ran
;
Dou, Dou
;
Diao, Yan-yan
;
Tong, Lin-jiang
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2020/07/01
B cell receptor
Bruton's tyrosine kinase
ibrutinib
small-molecule inhibitor
B cell malignancies
Discovery and Biological evaluation of pyrimido[4,5-d] pyrimidine-2,4(1H, 3H)-dione derivatives as potent Bruton's tyrosine kinase inhibitors
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2019, 卷号: 27, 期号: 15, 页码: 3390-3395
作者:
Diao, Yanyan
;
Fang, Xiaoyu
;
Song, Peiran
;
Lai, Mengzhen
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:70/0
  |  
提交时间:2020/07/01
Bruton's tyrosine kinase
B-cell malignancies
Potent inhibitors
Structure-activity relationship
Cellular activities
Discovery of a series of dimethoxybenzene FGFR inhibitors with 5H-pyrrolo[2,3-b]pyrazine scaffold: structure-activity relationship, crystal structural characterization and and in vivo study
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2019, 卷号: 9, 期号: 2, 页码: 351-368
作者:
Wei, Peng
;
Liu, Bo
;
Wang, Ruifeng
;
Gao, Yinglei
;
Li, Lanlan
  |  
收藏
  |  
浏览/下载:67/0
  |  
提交时间:2020/07/01
Fibroblast growth factor
Tyrosine kinase receptor
Structure-based
Crystallography
Selectivity
Hybrid
5-Hydrosulfonyl-5H- pyrrolo[2.3-b]pyrazine
Inhibitor
Chemical Constituents from the Heartwood of Haematoxylon campechianum as Protein Tyrosine Kinase Inhibitors
期刊论文
OAI收割
CHEMISTRY & BIODIVERSITY, 2014, 卷号: 11, 期号: 5, 页码: 776-783
作者:
Lin, Li-Gen
;
Xie, Hua
;
Wang, Yi-Tao
;
Ding, Jian
;
Ye, Yang
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Haematoxylon campechianum
Protein tyrosine kinases (PTKs)
Epihematoxylol B
Homoisoflavonoids
Hematoxylol B
10-O-methyl-
Kinase insert domain receptor (KDR)
Actinomycetes for Marine Drug Discovery Isolated from Mangrove Soils and Plants in China
期刊论文
OAI收割
MARINE DRUGS, 2009, 卷号: 7, 期号: 1, 页码: 24-44
作者:
Hong, Kui
;
Gao, An-Hui
;
Xie, Qing-Yi
;
Gao, Hao
;
Zhuang, Ling
  |  
收藏
  |  
浏览/下载:38/0
  |  
提交时间:2019/01/08
Mangroves
actinomycete diversity
marine drug discovery
high-throughput screening
growth inhibition
protein tyrosine phosphatase 1B
aurora kinase A
caspase 3
asesquiterpenequinonedysidinefromthespongedysideavillosaactivatestheinsulinpathwaythroughinhibitionofptpases
期刊论文
OAI收割
actapharmacologicasinica, 2009, 卷号: 30, 期号: 3, 页码: 333
作者:
Yu ZHANG
;
Yan LI
;
Yuewei GUO
;
Hualiang JIANG
;
Xu SHEN
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2020/07/01
TYROSINE-PHOSPHATASE 1B
STIMULATES GLUCOSE-UPTAKE
PROTEIN-KINASE INHIBITOR
3T3-L1 ADIPOCYTES
SELECTIVE INHIBITORS
GLUT4 TRANSLOCATION
PHOSPHOLIPASE A(2)
PLASMA-MEMBRANE
LEPTIN ACTION
SENSITIVITY
sesquiterpene quinone
dysidine
PTP1B
inhibitor
insulin
Effects of ginsenoside on brain-derived neurotrophic factor and tyrosine kinase B mRNA expression in the hippocampal formation of aged rats
期刊论文
OAI收割
NEURAL REGENERATION RESEARCH, 2008, 卷号: 3, 期号: 7, 页码: 723-727
作者:
Lai Hong
;
Liu Wensu
;
Li Zhaosheng
;
Zhao Haihua
;
Lue Yongli
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2021/02/02
SPINAL-CORD
BDNF
NEURONS
CELLS
TRKB
MEMORY
RG1
PROLIFERATION
NEUROGENESIS
PROGENITORS
ginsenosides
brain-derived neurotrophic factor
tyrosine kinase B
hippocampus