中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [15]
金属研究所 [2]
生物物理研究所 [1]
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上海神经科学研究所 [1]
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OAI收割 [24]
内容类型
期刊论文 [24]
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2019 [1]
2018 [1]
2017 [4]
2015 [1]
2014 [3]
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Biochemist... [1]
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Activation and function of receptor tyrosine kinases in human clear cell renal cell carcinomas
期刊论文
OAI收割
BMC CANCER, 2019, 卷号: 19, 期号: 1, 页码: 13
作者:
Zhang, Qing
;
Liu, Jian-He
;
Liu, Jing-Li
;
Qi, Chun-Ting
;
Yan, Lei
  |  
收藏
  |  
浏览/下载:76/0
  |  
提交时间:2020/07/01
Receptor tyrosine kinases (RTKs)
Activation and function
Clear cell renal cell carcinomas (ccRCCs)
Targeted therapy
PDGFR beta
Stroma cells
PBA2 exhibits potent anti-tumor activity via suppression of VEGFR2 mediated-cell proliferation and angiogenesis
期刊论文
OAI收割
BIOCHEMICAL PHARMACOLOGY, 2018, 卷号: 150, 页码: 131-140
作者:
Fang, Xiaona
;
Xie, Hua
;
Luo, Min
;
Chen, Zhen
;
Wang, Fang
  |  
收藏
  |  
浏览/下载:44/0
  |  
提交时间:2019/01/08
Angiogenesis
And-tumor activity
Multi-tyrosine kinases inhibitor
PBA2
VEGFR2
Evaluation of in vitro and in vivo activity of a multityrosine kinase inhibitor, AL3810, against human thyroid cancer
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 11, 页码: 1533-1542
作者:
Xie, Qin
;
Chen, Hui
;
Ai, Jing
;
Gao, Ying-lei
;
Geng, Mei-yu
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2019/01/08
thyroid cancer
AL3810
multi-tyrosine kinases inhibitor
angiogenesis
RET
Synthesis and Activity Evaluation of Novel 3,4-Dihydro-benzo[b]-oxazepin-5(2H)-one Derivatives as Protein Kinases Inhibitors
期刊论文
OAI收割
CHINESE JOURNAL OF ORGANIC CHEMISTRY, 2017, 卷号: 37, 期号: 6, 页码: 1463-1472
作者:
Hou Guige
;
Jiang Chengshi
;
Liu Hongchun
;
Tong Linjiang
;
Peng Xia
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2019/01/08
3,4-dihydro-benzo[b]oxazepin-5(2H)-one derivatives
synthesis
protein-tyrosine kinases inhibitors
ErbB1
ErbB2
Concomitant inhibition of receptor tyrosine kinases and downstream AKT synergistically inhibited growth of KRAS/BRAF mutant colorectal cancer cells
期刊论文
OAI收割
ONCOTARGET, 2017, 卷号: 8, 期号: 3, 页码: 5003-5015
作者:
Song, Qiaoling
;
Sun, Xiaoxiao
;
Guo, Hui
;
Yu, Qiang
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2019/01/08
receptor tyrosine kinases
AKT
colorectal cancer
drug combination
RAS/RAF
evaluationofinvitroandinvivoactivityofamultityrosinekinaseinhibitoral3810againsthumanthyroidcancer
期刊论文
OAI收割
actapharmacologicasinica, 2017, 卷号: 38, 期号: 11, 页码: 1533
作者:
Xie Qin
;
Chen Hui
;
Al Jing
;
Gao Yinglei
;
Geng Meiyu
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
TARGETED THERAPIES
RET
CARCINOMA
MODELS
GROWTH
TUMORS
CELLS
thyroid cancer
AL3810
multi-tyrosine kinases inhibitor
angiogenesis
RET
Design, Synthesis and Antitumor Activity of Novel 6,7-Dimethoxyquinazoline Derivatives Containing Diaryl Urea Moiety
期刊论文
OAI收割
CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 2015, 卷号: 31, 期号: 5, 页码: 766-773
作者:
Hou Yunlei
;
Wu Shasha
;
Ma Longsheng
;
Bai Jinying
;
Liu Zijian
  |  
收藏
  |  
浏览/下载:59/0
  |  
提交时间:2021/02/02
RECEPTOR TYROSINE KINASES
BIOLOGICAL EVALUATION
HIGHLY POTENT
INHIBITOR
IDENTIFICATION
GROWTH
DISCOVERY
SORAFENIB
EGFR
6,7-Dimethoxyquinazoline derivative
Diaryl urea scaffold
Cytotoxic activity
HSP90 inhibitor AUY922 abrogates up-regulation of RTKs by mTOR inhibitor AZD8055 and potentiates its antiproliferative activity in human breast cancer
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF CANCER, 2014, 卷号: 135, 期号: 10, 页码: 2462-2474
作者:
Chen, Si-Meng
;
Guo, Chen-Liang
;
Shi, Jia-Jie
;
Xu, Yi-Chao
;
Chen, Yi
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2019/01/08
mTOR kinase inhibitor
HSP90 inhibitor
breast cancer
receptor tyrosine kinases
drug combination
Chemical Constituents from the Heartwood of Haematoxylon campechianum as Protein Tyrosine Kinase Inhibitors
期刊论文
OAI收割
CHEMISTRY & BIODIVERSITY, 2014, 卷号: 11, 期号: 5, 页码: 776-783
作者:
Lin, Li-Gen
;
Xie, Hua
;
Wang, Yi-Tao
;
Ding, Jian
;
Ye, Yang
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2019/01/08
Haematoxylon campechianum
Protein tyrosine kinases (PTKs)
Epihematoxylol B
Homoisoflavonoids
Hematoxylol B
10-O-methyl-
Kinase insert domain receptor (KDR)
Aqueous extract of Taxus Chinensis (Pilger) Rehd inhibits lung carcinoma A549 cells through the epidermal growth factor receptor/mitogen-activated protein kinase pathway in vitro and in vivo
期刊论文
OAI收割
JOURNAL OF TRADITIONAL CHINESE MEDICINE, 2014, 卷号: 34
-
  |  
收藏
  |  
浏览/下载:17/0
  |  
提交时间:2020/10/26
PHARMACOLOGICAL TESTING METHOD
VAR. MAIREI
TYROSINE PHOSPHORYLATION
HUMAN TUMORS
CANCER
EXPRESSION
THERAPY
MAPK
PROLIFERATION
Taxus
Lung neoplasms
Receptor
epidermal growth factor
Mitogen-activated protein kinases
In vitro
In vivo