中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页
机构
成果
学者
登录
注册
登陆
×
验证码:
换一张
忘记密码?
记住我
×
校外用户登录
CAS IR Grid
机构
上海药物研究所 [19]
生态环境研究中心 [3]
昆明植物研究所 [2]
海洋研究所 [2]
植物研究所 [2]
计算技术研究所 [1]
更多
采集方式
OAI收割 [32]
内容类型
期刊论文 [31]
学位论文 [1]
发表日期
2022 [32]
学科主题
Agricultur... [1]
Biology [1]
Genetics &... [1]
筛选
浏览/检索结果:
共32条,第1-10条
帮助
限定条件
发表日期:2022
条数/页:
5
10
15
20
25
30
35
40
45
50
55
60
65
70
75
80
85
90
95
100
排序方式:
请选择
题名升序
题名降序
提交时间升序
提交时间降序
作者升序
作者降序
发表日期升序
发表日期降序
Structure-Based Design of Tropane Derivatives as a Novel Series of CCR5 Antagonists with Broad-Spectrum Anti-HIV-1 Activities and Improved Oral Bioavailability
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 24, 页码: 16526-16540
作者:
Xie, Xiong
;
Zheng, Yu-Gui
;
Chen, Huan
;
Li, Jian
;
Luo, Rong-Hua
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/04/10
Synthesis of maleimide-braced peptide macrocycles and their potential anti-SARS-CoV-2 mechanisms
期刊论文
OAI收割
CHEMICAL COMMUNICATIONS, 2022, 页码: 4
作者:
Li, Jian
;
Sun, Jina
;
Zhang, Xianglei
;
Zhang, Ruxue
;
Wang, Qian
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/04/10
In vitro and in vivo evaluation of the main protease inhibitor FB2001 against SARS-CoV-2
期刊论文
OAI收割
ANTIVIRAL RESEARCH, 2022, 卷号: 208, 页码: 10
作者:
Shang, Weijuan
;
Dai, Wenhao
;
Yao, Cheng
;
Xu, Ling
;
Tao, Xiangming
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
SARS-CoV-2
SARS-CoV-2 variants
FB2001
Main protease
PBPK
Anti-SARS-CoV-2 in vivo
Antiviral drug design based on structural insights into the N-terminal domain and C-terminal domain of the SARS-CoV-2 nucleocapsid protein
期刊论文
OAI收割
SCIENCE BULLETIN, 2022, 卷号: 67, 期号: 22, 页码: 2327-2335
作者:
Luan, Xiaodong
;
Li, Xinming
;
Li, Yufan
;
Su, Gengchen
;
Yin, Wanchao
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2023/04/10
SARS-CoV-2
Nucleocapsid protein
N-terminal domain
Ceftriaxone sodium
Predicting In Vitro and In Vivo Anti-SARS-CoV-2 Activities of Antivirals by Intracellular Bioavailability and Biochemical Activity
期刊论文
OAI收割
ACS OMEGA, 2022, 页码: 13
作者:
Zhang, Jinwen
;
He, Mingfeng
;
Xie, Qian
;
Su, Ailing
;
Yang, Kuangyang
  |  
收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/04/10
Design, synthesis and biological evaluation of novel dihydrobenzodioxine derivatives as HBV capsid protein inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 128, 页码: 12
作者:
Liu, Linyue
;
Li, Chuanju
;
Xie, Yong
;
Zhang, Lei
;
Chen, Yunfu
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
HBV
Capsid protein inhibitors
Pharmacophore hybrid
Scaffold hopping
HepAD38 cells
Structure-based design of a novel inhibitor of the ZIKA virus NS2B/ NS3 protease
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 128, 页码: 7
作者:
Xiong, Yanchao
;
Cheng, Fei
;
Zhang, Junyi
;
Su, Haixia
;
Hu, Hangchen
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/11/11
Zika virus
Fragment -based hit screening
Protein -inhibitor interactions
NS2B
NS3 protease
Crystal structure
Deciphering COVID-19 host transcriptomic complexity and variations for therapeutic discovery against new variants
期刊论文
OAI收割
ISCIENCE, 2022, 卷号: 25, 期号: 10, 页码: 28
作者:
Xing, Jing
;
Shankar, Rama
;
Ko, Meehyun
;
Zhang, Keke
;
Zhang, Sulin
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/11/11
Pooled resequencing of larvae and adults reveals genomic variations associated with Ostreid herpesvirus 1 resistance in the Pacific oyster Crassostrea gigas
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2022, 卷号: 13, 页码: 17
作者:
Yao, Shanshan
;
Li, Li
;
Guan, Xudong
;
He, Yan
;
Jouaux, Aude
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2023/01/12
Ostreid herpesvirus
antiviral innate immunity
oyster
pooled-resequencing
transcriptomic response
disease resistance
larval mortality
molluscan aquaculture
Improved Synthesis of Key Intermediate of Baloxavir Marboxil, an Anti-Influenza Drug
期刊论文
OAI收割
CHEMISTRYSELECT, 2022, 卷号: 7, 期号: 29, 页码: 5
作者:
Hu, Zhenfei
;
Li, Maocheng
;
Meng, Xin
;
Guo, Bin
  |  
收藏
  |  
浏览/下载:53/0
  |  
提交时间:2022/08/30
antiviral agents
key intermediate
process research
synthesis design