中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [43]
昆明植物研究所 [18]
武汉病毒研究所 [10]
南海海洋研究所 [8]
昆明动物研究所 [7]
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期刊论文 [116]
学位论文 [4]
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A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 10
作者:
Zhang, Yumin
;
Sun, Yuan
;
Xie, Yuanchao
;
Shang, Weijuan
;
Wang, Zhen
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/08
Ocellatuspyrones A-G, new antibacterial polypropionates from the Chinese mollusk Placobranchus ocellatus
期刊论文
OAI收割
MARINE LIFE SCIENCE & TECHNOLOGY, 2023, 页码: 14
作者:
Li, Song-Wei
;
Yu, Dan-Dan
;
Su, Ming-Zhi
;
Yao, Li-Gong
;
Wang, Hong
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/10/17
Placobranchus ocellatus
gamma-pyrone polypropionate
Photosynthetic mollusk
Antibacterial activity
Stereochemistry
Discovery and mechanism of action of Thonzonium bromide from an FDA-approved drug library with potent and broad-spectrum inhibitory activity against main proteases of human coronaviruses
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 11
作者:
Wang, Ruyu
;
Zhai, Guanglei
;
Zhu, Guanghao
;
Wang, Mengge
;
Gong, Xiaoyi
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2023/04/10
SARS-CoV-23CLpro
Thonzonium bromide
Mechanism of action
Broad-spectrum inhibitor
Structure-Based Design of Tropane Derivatives as a Novel Series of CCR5 Antagonists with Broad-Spectrum Anti-HIV-1 Activities and Improved Oral Bioavailability
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 24, 页码: 16526-16540
作者:
Xie, Xiong
;
Zheng, Yu-Gui
;
Chen, Huan
;
Li, Jian
;
Luo, Rong-Hua
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/04/10
Improved Synthesis of Key Intermediate of Baloxavir Marboxil, an Anti-Influenza Drug
期刊论文
OAI收割
CHEMISTRYSELECT, 2022, 卷号: 7, 期号: 29, 页码: 5
作者:
Hu, Zhenfei
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2022/08/30
antiviral agents
key intermediate
process research
synthesis design
Hemin protects against Zika virus infection by disrupting virus-endosome fusion
期刊论文
OAI收割
ANTIVIRAL RESEARCH, 2022, 卷号: 203, 页码: 11
作者:
Xu, Meng-Meng
;
Wu, Bing
;
Huang, Guan-Gen
;
Feng, Chun-Lan
;
Wang, Xiao-Han
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2022/08/16
Zika virus
Hemin
Antiviral
Inflammation
HO-1
Viral fusion
Natural products for infectious microbes and diseases: an overview of sources, compounds, and chemical diversities
期刊论文
OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2022, 卷号: 65, 期号: 6, 页码: 1123-1145
作者:
Luo, Lu
;
Yang, Jun
;
Wang, Cheng
;
Wu, Jie
;
Li, Yafang
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2024/03/07
natural product
infectious pathogen
drug discovery
drug development
in silico analysis
TANK-binding kinase 1 (TBK1): An emerging therapeutic target for drug discovery
期刊论文
OAI收割
DRUG DISCOVERY TODAY, 2021, 卷号: 26, 期号: 10, 页码: 2445-2455
作者:
Xiang, Shuang
;
Song, Shukai
;
Tang, Haotian
;
Smaill, Jeff B.
;
Wang, Aiqun
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2021/12/01
Antibiotic resistance
Computational biology
Databases
In silico tools
What coronavirus 3C-like protease tells us: From structure, substrate selectivity, to inhibitor design
期刊论文
OAI收割
MEDICINAL RESEARCH REVIEWS, 2021, 页码: 34
作者:
Xiong, Muya
;
Su, Haixia
;
Zhao, Wenfeng
;
Xie, Hang
;
Shao, Qiang
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2021/05/24
3C-like protease
binding modes
coronavirus
inhibitors
structure and function
Antiviral nanoagents: More attention and effort needed?
期刊论文
OAI收割
NANO TODAY, 2020, 卷号: 35, 页码: 1-14
作者:
Chen, Yongjiu
;
Ma, Juan
;
Xu, Ming
;
Liu, Sijin
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/09/14
Engineered nanomaterials
Antivirus
Nanoagents
Therapeutics
Mechanism