机构

• 昆明植物研究所 [9]

采集方式

• OAI收割 [9]

内容类型

• 期刊论文 [9]

发表日期

• 2020 [1]
• 2019 [2]
• 2018 [2]
• 2015 [3]
• 2013 [1]

学科主题

• Biochemist... [1]
• Biochemist... [1]

筛选

浏览/检索结果: 共9条，第1-9条 帮助 限定条件 专题：昆明植物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 Parthenolide inhibits ubiquitin-specific peptidase 7 (USP7), Wnt signaling, and colorectal cancer cell growth 期刊论文  OAI收割 JOURNAL OF BIOLOGICAL CHEMISTRY, 2020 作者:  Li, Xue;  Kong, Lingmei;  Yang, Qihong;  Duan, Aizhu;  Ju, Xiaoman   |  收藏  |  浏览/下载：12/0  |  提交时间：2021/01/05 The natural product antroalbol H promotes phosphorylation of liver kinase B1 (LKB1) at threonine 189 and thereby enhances cellular glucose uptake 期刊论文  OAI收割 JOURNAL OF BIOLOGICAL CHEMISTRY, 2019, 卷号: 294, 期号: 27, 页码: 10415-10427 作者:  Wang, Fang;  Yang, Xiaoyan;  Lu, Yanting;  Li, Zhenghui;  Xu, Yuhui   |  收藏  |  浏览/下载：77/0  |  提交时间：2019/09/10 glucose metabolism  liver kinase B1 (LKB1)  AMP-activated kinase (AMPK)  glucose transporter type 4 (GLUT4)  fungi  Basidiomycete  diabetes  energy sensing  glucose homeostasis  sesquiterpene   Celastrol Protects From Cholestatic Liver Injury Through Modulation of SIRT1-FXR Signaling 期刊论文  OAI收割 MOLECULAR & CELLULAR PROTEOMICS, 2019, 卷号: 18, 期号: 3, 页码: 520-533 作者:  Zhao, Qi;  Liu, Fang;  Cheng, Yan;  Xiao, Xue-Rong;  Hu, Dan-Dan   |  收藏  |  浏览/下载：58/0  |  提交时间：2019/07/29 Natural cyclopeptide RA-V inhibits the NF-kappa B signaling pathway by targeting TAK1 期刊论文  OAI收割 PHYTOTAXA, 2018, 卷号: 356, 期号: 4, 页码: 267-275 作者:  Wang, Zhe;  Zhao, Simeng;  Song, Lihua;  Pu, Yuzhi;  Wang, Qiang   |  收藏  |  浏览/下载：40/0  |  提交时间：2018/12/27 Natural cyclopeptide RA-V inhibits the NF-kappa B signaling pathway by targeting TAK1 期刊论文  OAI收割 CELL DEATH & DISEASE, 2018, 卷号: 9, 页码: 715 作者:  Wang, Zhe;  Zhao, Simeng;  Song, Lihua;  Pu, Yuzhi;  Wang, Qiang   |  收藏  |  浏览/下载：43/0  |  提交时间：2019/03/29 Rubicordins A-C, new cyclopeptides from Rubia cordifolia with cytotoxicity and inhibiting NF-kappa B signaling pathway 期刊论文  OAI收割 TETRAHEDRON, 2015, 卷号: 71, 期号: 52, 页码: 9673-9678 作者:  Chen, Xiao-Qiang;  Zhao, Si-Meng;  Wang, Zhe;  Zeng, Guang-Zhi;  Huang, Mao-Bo 收藏  |  浏览/下载：53/0  |  提交时间：2016/02/01 Rubia cordifolia  Rubicordins A-C  Cyclopeptides  Cytotoxicity  NF-kappa B signaling pathway   RA-XII inhibits tumour growth and metastasis in breast tumour-bearing mice via reducing cell adhesion and invasion and promoting matrix degradation 期刊论文  OAI收割 SCIENTIFIC REPORTS, 2015, 卷号: 5 作者:  Leung,Hoi-Wing;  Zhao,Si-Meng;  Yue,Grace Gar-Lee;  Lee,Julia Kin-Ming;  Fung,Kwok-Pui 收藏  |  浏览/下载：23/0  |  提交时间：2016/01/19 Cyclopeptide RA-V inhibits cell adhesion and invasion in both estrogen receptor positive and negative breast cancer cells via PI3K/AKT and NF-kappa B signaling pathways 期刊论文  OAI收割 BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2015, 卷号: 1853, 期号: 8, 页码: 1827-1840 作者:  Leung, Hoi-Wing;  Wang, Zhe;  Yue, Grace Gar-Lee;  Zhao, Si-Meng;  Lee, Julia Kin-Ming 收藏  |  浏览/下载：54/0  |  提交时间：2015/07/20 Cyclopeptide  Cell adhesion  Cell invasion  Metastasis  Breast cancer   Apoptosis induction and G2/M arrest of 2-methyl-1,3,6-trihydroxy-9,10-anthraquinone from Rubia yunnanensis in human cervical cancer HeLa cells 期刊论文  OAI收割 PHARMAZIE, 2013, 卷号: 68, 期号: 4, 页码: 293-299 作者:  Zeng, Guang-Zhi;  Fan, Jun-Ting;  Xu, Jun-Ju;  Li, Yan;  Tan, Ning-Hua 收藏  |  浏览/下载：26/0  |  提交时间：2015/05/14 2-Methyl-1,3,6-trihydroxy-9,10-anthraquinone (MTA)  one of the major components isolated from the traditional  Chinese medicine Rubia yunnanensis  exhibited inhibitory activity on the proliferation of several  human cancer cell lines. The results from an annexin V-FITC (fluoresein-5-isothiocyanate) apoptosis assay  and DNA content analysis showed that MTA exerted cytotoxicity via apoptosis induction and G2/M cell cycle  arrest in human cervical carcinoma HeLa cells. Further  MTA was found to induce apoptosis of HeLa cells  through the mitochondria-mediated pathway. It caused the translocation of Bax to the mitochondria and  release of cytochrome c into the cytosol  which caused the cleavage of caspase and poly(ADP-ribose)  polymerase and finally triggered the apoptosis. Furthermore  the p53/p21/Cdc2-cyclin B1 signaling was  found related to the G2/M arrest caused by MTA. The over-expression of p21 and down-expression of  cyclin B1 caused by MTA inactivated the Cdc2-cyclin B1 complex of G2/M checkpoint and finally caused  the G2/M arrest in HeLa cells. This study demonstrated that MTA is a potential anti-cancer component of  R. yunnanensis  a folk anti-cancer herb used in Yunnan  China.