中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  1. CAS IR Grid
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  • 上海药物研究所 [16]
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发表日期
  • 2023 [16]
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浏览/检索结果: 共16条，第1-10条 帮助

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Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025
作者:  Cheng, Jing;  Yan, Ziqin;  Jiang, Kailong;  Liu, Chen;  Xu, Dehua
  |  收藏  |  浏览/下载：6/0  |  提交时间：2024/02/19
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:  Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan
  |  收藏  |  浏览/下载：11/0  |  提交时间：2023/12/11
Exosomes: New Insights into the Pathogenesis of Metabolic Syndrome 期刊论文  OAI收割
BIOLOGY-BASEL, 2023, 卷号: 12, 期号: 12, 页码: 14
作者:  Wang, Ning;  Li, Jing;  Hu, Zixuan;  Ngowi, Ebenezeri Erasto;  Yan, Baolong
  |  收藏  |  浏览/下载：16/0  |  提交时间：2024/02/27
Natural product P57 induces hypothermia through targeting pyridoxal kinase 期刊论文  OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15
作者:  Wang, Ruina;  Xiao, Lei;  Pan, Jianbo;  Bao, Guangsen;  Zhu, Yunmei
  |  收藏  |  浏览/下载：30/0  |  提交时间：2024/02/19
Hyodeoxycholic acid ameliorates nonalcoholic fatty liver disease by inhibiting RAN-mediated PPARa nucleus-cytoplasm shuttling 期刊论文  OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 18
作者:  Zhong, Jing;  He, Xiaofang;  Gao, Xinxin;  Liu, Qiaohong;  Zhao, Yu
  |  收藏  |  浏览/下载：5/0  |  提交时间：2023/12/08
Spectral and biodistributional engineering of deep near-infrared chromophore 期刊论文  OAI收割
CHINESE CHEMICAL LETTERS, 2023, 卷号: 34, 期号: 9, 页码: 7
作者:  Dong, Yan;  Lu, Xicun;  Li, Yi;  Chen, Weichao;  Yin, Lei
  |  收藏  |  浏览/下载：22/0  |  提交时间：2023/10/17
Investigation of targets and anticancer mechanisms of covalently acting natural products by functional proteomics 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 卷号: 44, 期号: 8, 页码: 1701-1711
作者:  Zhao, Wen-si;  Chen, Kai-feng;  Liu, Man;  Jia, Xing-long;  Huang, Yu-qi
  |  收藏  |  浏览/下载：2/0  |  提交时间：2024/03/27
Identification of XAF1 as an endogenous AKT inhibitor 期刊论文  OAI收割
CELL REPORTS, 2023, 卷号: 42, 期号: 7, 页码: 25
作者:  Chen, Min;  Wang, Kangjunjie;  Han, Ying;  Yan, Shukun;  Yuan, Huairui
  |  收藏  |  浏览/下载：13/0  |  提交时间：2023/10/17
Prime editing-based gene correction alleviates the hyperexcitable phenotype and seizures of a genetic epilepsy mouse model 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 4
作者:  Cao, Bi-rong;  Huang, Yi-ming;  Tian, Fu-yun;  Li, Jin-hui;  Xu, Chun-long
  |  收藏  |  浏览/下载：28/0  |  提交时间：2023/10/17
The PIWI-specific insertion module helps load longer piRNAs for translational activation essential for male fertility 期刊论文  OAI收割
SCIENCE CHINA-LIFE SCIENCES, 2023, 页码: 23
作者:  Wang, Xin;  Lin, Di-Hang;  Yan, Yue;  Wang, An-Hui;  Liao, Jiaoyang
  |  收藏  |  浏览/下载：26/0  |  提交时间：2023/10/17