中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [176]
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OAI收割 [176]
内容类型
期刊论文 [173]
会议论文 [3]
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2024 [5]
2023 [16]
2022 [15]
2021 [8]
2020 [11]
2019 [15]
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Pharmacolo... [3]
Chemistry [2]
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浏览/检索结果:
共176条,第1-10条
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专题:上海药物研究所
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Biotransformation and disposition characteristics of HSK7653, a novel long-acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes
期刊论文
OAI收割
DIABETES OBESITY & METABOLISM, 2024, 页码: 9
作者:
Bian, Yi-cong
;
Meng, Jian
;
Hu, Tao
;
Ma, Sheng
;
Huang, Chen-rong
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2024/05/22
HSK7653
long-acting dipeptidyl peptidase-4 inhibitor
mass balance
metabolism
pharmacokinetics
radiolabelled
Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1
期刊论文
OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 14
作者:
Xie, Xiong
;
Lan, Qiaoshuai
;
Zhao, Jinyi
;
Zhang, Sulin
;
Liu, Lu
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses
期刊论文
OAI收割
NATURE CHEMICAL BIOLOGY, 2024, 页码: 29
作者:
Zhou, Xiaoyu
;
Zhao, Cheng
;
Xu, Haiyan
;
Xu, Yixiang
;
Zhan, Li
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/03/25
Comprehensive analysis of phenylpropanoids and butylidenephthalides in
Angelica sinensis
(Oliv.) Diels from different regions and processing methods by high-performance liquid chromatography combined with chemometrics
期刊论文
OAI收割
EUROPEAN FOOD RESEARCH AND TECHNOLOGY, 2024, 页码: 16
作者:
Sun, Yan
;
Zhou, Jing
;
Hu, Yuxin
;
Chen, Sihan
;
Ni, Hui
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2024/02/27
Angelicae Sinensis radix
Origin
Chemometrics
Fingerprints
Single standard to determine the multi-components
Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies
期刊论文
OAI收割
CELL, 2024, 卷号: 187, 期号: 1, 页码: 49
作者:
Liu, Qian
;
Zhang, Jing
;
Guo, Chenchen
;
Wang, Mengcheng
;
Wang, Chenfei
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/02/27
Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025
作者:
Cheng, Jing
;
Yan, Ziqin
;
Jiang, Kailong
;
Liu, Chen
;
Xu, Dehua
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2024/02/19
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects
期刊论文
OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:
Yang, Xin-Mei
;
Yang, Yang
;
Yao, Bu-Fan
;
Ye, Pan-Pan
;
Xu, Yan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/12/11
COVID-19
Simnotrelvir
Safety
Pharmacokinetics
Healthy subjects
Exosomes: New Insights into the Pathogenesis of Metabolic Syndrome
期刊论文
OAI收割
BIOLOGY-BASEL, 2023, 卷号: 12, 期号: 12, 页码: 14
作者:
Wang, Ning
;
Li, Jing
;
Hu, Zixuan
;
Ngowi, Ebenezeri Erasto
;
Yan, Baolong
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2024/02/27
exosome
biogeneration
function
metabolic syndrome
Natural product P57 induces hypothermia through targeting pyridoxal kinase
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15
作者:
Wang, Ruina
;
Xiao, Lei
;
Pan, Jianbo
;
Bao, Guangsen
;
Zhu, Yunmei
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2024/02/19
Hyodeoxycholic acid ameliorates nonalcoholic fatty liver disease by inhibiting RAN-mediated PPARa nucleus-cytoplasm shuttling
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 18
作者:
Zhong, Jing
;
He, Xiaofang
;
Gao, Xinxin
;
Liu, Qiaohong
;
Zhao, Yu
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/08