中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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  • 上海药物研究所 [176]
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Biotransformation and disposition characteristics of HSK7653, a novel long-acting dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes 期刊论文  OAI收割
DIABETES OBESITY & METABOLISM, 2024, 页码: 9
作者:  
Bian, Yi-cong;  Meng, Jian;  Hu, Tao;  Ma, Sheng;  Huang, Chen-rong
  |  收藏  |  浏览/下载:0/0  |  提交时间:2024/05/22
Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1 期刊论文  OAI收割
SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2024, 卷号: 9, 期号: 1, 页码: 14
作者:  
Xie, Xiong;  Lan, Qiaoshuai;  Zhao, Jinyi;  Zhang, Sulin;  Liu, Lu
  |  收藏  |  浏览/下载:1/0  |  提交时间:2024/05/07
Pharmacological inhibition of Kir4.1 evokes rapid-onset antidepressant responses 期刊论文  OAI收割
NATURE CHEMICAL BIOLOGY, 2024, 页码: 29
作者:  
Zhou, Xiaoyu;  Zhao, Cheng;  Xu, Haiyan;  Xu, Yixiang;  Zhan, Li
  |  收藏  |  浏览/下载:16/0  |  提交时间:2024/03/25
Comprehensive analysis of phenylpropanoids and butylidenephthalides in Angelica sinensis (Oliv.) Diels from different regions and processing methods by high-performance liquid chromatography combined with chemometrics 期刊论文  OAI收割
EUROPEAN FOOD RESEARCH AND TECHNOLOGY, 2024, 页码: 16
作者:  
Sun, Yan;  Zhou, Jing;  Hu, Yuxin;  Chen, Sihan;  Ni, Hui
  |  收藏  |  浏览/下载:18/0  |  提交时间:2024/02/27
Proteogenomic characterization of small cell lung cancer identifies biological insights and subtype-specific therapeutic strategies 期刊论文  OAI收割
CELL, 2024, 卷号: 187, 期号: 1, 页码: 49
作者:  
Liu, Qian;  Zhang, Jing;  Guo, Chenchen;  Wang, Mengcheng;  Wang, Chenfei
  |  收藏  |  浏览/下载:9/0  |  提交时间:2024/02/27
Discovery of JN122, a Spiroindoline-Containing Molecule that Inhibits MDM2/p53 Protein-Protein Interaction and Exerts Robust In Vivo Antitumor Efficacy 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16991-17025
作者:  
Cheng, Jing;  Yan, Ziqin;  Jiang, Kailong;  Liu, Chen;  Xu, Dehua
  |  收藏  |  浏览/下载:6/0  |  提交时间:2024/02/19
A first-in-human phase 1 study of simnotrelvir, a 3CL-like protease inhibitor for treatment of COVID-19, in healthy adult subjects 期刊论文  OAI收割
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2023, 卷号: 191, 页码: 9
作者:  
Yang, Xin-Mei;  Yang, Yang;  Yao, Bu-Fan;  Ye, Pan-Pan;  Xu, Yan
  |  收藏  |  浏览/下载:11/0  |  提交时间:2023/12/11
Exosomes: New Insights into the Pathogenesis of Metabolic Syndrome 期刊论文  OAI收割
BIOLOGY-BASEL, 2023, 卷号: 12, 期号: 12, 页码: 14
作者:  
Wang, Ning;  Li, Jing;  Hu, Zixuan;  Ngowi, Ebenezeri Erasto;  Yan, Baolong
  |  收藏  |  浏览/下载:16/0  |  提交时间:2024/02/27
Natural product P57 induces hypothermia through targeting pyridoxal kinase 期刊论文  OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 15
作者:  
Wang, Ruina;  Xiao, Lei;  Pan, Jianbo;  Bao, Guangsen;  Zhu, Yunmei
  |  收藏  |  浏览/下载:30/0  |  提交时间:2024/02/19
Hyodeoxycholic acid ameliorates nonalcoholic fatty liver disease by inhibiting RAN-mediated PPARa nucleus-cytoplasm shuttling 期刊论文  OAI收割
NATURE COMMUNICATIONS, 2023, 卷号: 14, 期号: 1, 页码: 18
作者:  
Zhong, Jing;  He, Xiaofang;  Gao, Xinxin;  Liu, Qiaohong;  Zhao, Yu
  |  收藏  |  浏览/下载:5/0  |  提交时间:2023/12/08