中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [55]
采集方式
OAI收割 [55]
内容类型
期刊论文 [55]
发表日期
2024 [2]
2023 [2]
2022 [5]
2021 [5]
2020 [2]
2018 [8]
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专题:上海药物研究所
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Discovery of novel SOS1 inhibitors using machine learning
期刊论文
OAI收割
RSC MEDICINAL CHEMISTRY, 2024, 卷号: 15, 期号: 4, 页码: 1392-1403
作者:
Duo, Lihui
;
Chen, Yi
;
Liu, Qiupei
;
Ma, Zhangyi
;
Farjudian, Amin
  |  
收藏
  |  
浏览/下载:1/0
  |  
提交时间:2024/05/07
Sesquiterpenoids and Cytochalasins with Immunosuppressive Activity from
Sonchus wightianus
期刊论文
OAI收割
CHEMISTRY & BIODIVERSITY, 2024, 页码: 9
作者:
Xie, Zhi-Xiang
;
Cui, Yong-Sheng
;
Liu, Xi-Hong
;
Yao, Jia-Ying
;
He, Shi-Jun
  |  
收藏
  |  
浏览/下载:3/0
  |  
提交时间:2024/05/07
Sonchus wightianus
guaiane-type sesquiterpenoid
cytochalasin
electronic circular dichroism
immunosuppressive activity
TI17, a novel compound, exerts anti-MM activity by impairing Trip13 function of DSBs repair and enhancing DNA damage
期刊论文
OAI收割
CANCER MEDICINE, 2023, 页码: 14
作者:
Chang, Shuaikang
;
Xiao, Wenqin
;
Xie, Yongsheng
;
Xu, Zhijian
;
Li, Bo
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/11
DNA damage
DSBs repair
myeloma
TI17
Trip13
A pilot study of the differentiated landscape of peripheral blood mononuclear cells from children with incomplete versus complete Kawasaki disease
期刊论文
OAI收割
WORLD JOURNAL OF PEDIATRICS, 2023, 页码: 12
作者:
Sun, Shu-Na
;
Zhou, Yan
;
Fu, Xing
;
Zheng, Yuan-Zheng
;
Xie, Cao
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/10/17
Structure-Based Design of Tropane Derivatives as a Novel Series of CCR5 Antagonists with Broad-Spectrum Anti-HIV-1 Activities and Improved Oral Bioavailability
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 24, 页码: 16526-16540
作者:
Xie, Xiong
;
Zheng, Yu-Gui
;
Chen, Huan
;
Li, Jian
;
Luo, Rong-Hua
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2023/04/10
Design, synthesis and biological evaluation of novel dihydrobenzodioxine derivatives as HBV capsid protein inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2022, 卷号: 128, 页码: 12
作者:
Liu, Linyue
;
Li, Chuanju
;
Xie, Yong
;
Zhang, Lei
;
Chen, Yunfu
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
HBV
Capsid protein inhibitors
Pharmacophore hybrid
Scaffold hopping
HepAD38 cells
Preclinical validation and phase I trial of 4-hydroxysalicylanilide, targeting ribonucleotide reductase mediated dNTP synthesis in multiple myeloma
期刊论文
OAI收割
Journal of Biomedical Science, 2022, 卷号: 29, 期号: 1
作者:
Xie,Yongsheng
;
Wang,Yingcong
;
Xu,Zhijian
;
Lu,Yumeng
;
Song,Dongliang
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/06/15
4-Hydroxysalicylanilid
Ribonucleotide reductase
Deoxyribonucleotides
DNA damage repair
Multiple myeloma
Design, Synthesis, and Biological Evaluation of Peptidomimetic Aldehydes as Broad-Spectrum Inhibitors against Enterovirus and SARS-CoV-2
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 4, 页码: 2794-2808
作者:
Dai, Wenhao
;
Jochmans, Dirk
;
Xie, Hang
;
Yang, Hang
;
Li, Jian
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/08/16
DCZ0014, a novel compound in the therapy of diffuse large B-cell lymphoma via the B cell receptor signaling pathway
期刊论文
OAI收割
NEOPLASIA, 2022, 卷号: 24, 期号: 1, 页码: 50-61
作者:
Chang, Shuaikang
;
Li, Bo
;
Xie, Yongsheng
;
Wang, Yingcong
;
Xu, Zhijian
  |  
收藏
  |  
浏览/下载:25/0
  |  
提交时间:2022/06/15
Diffuse large B cell lymphoma
DCZ0014
Apoptosis
Lyn
Syk
SARS-CoV-2 envelope protein causes acute respiratory distress syndrome (ARDS)-like pathological damages and constitutes an antiviral target
期刊论文
OAI收割
CELL RESEARCH, 2021, 页码: 14
作者:
Xia, Bingqing
;
Shen, Xurui
;
He, Yang
;
Pan, Xiaoyan
;
Liu, Feng-Liang
  |  
收藏
  |  
浏览/下载:75/0
  |  
提交时间:2021/08/17