机构

• 上海药物研究所 [25]

采集方式

• OAI收割 [25]

内容类型

• 期刊论文 [25]

发表日期

• 2023 [1]
• 2022 [1]
• 2021 [1]
• 2020 [1]
• 2017 [1]
• 2016 [1]
• 更多

学科主题

• Chemistry [2]
• Pharmacolo... [2]
• Cell Biolo... [1]

筛选

浏览/检索结果: 共25条，第1-10条 帮助 限定条件 专题：上海药物研究所    第一署名单位    第一作者单位    通讯作者单位     条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序题名升序题名降序作者升序作者降序发表日期升序发表日期降序 Peptide-functionalized therapeutic nanoplatform for treatment orthotopic triple negative breast cancer and bone metastasis 期刊论文  OAI收割 NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2023, 卷号: 50, 页码: 102669 作者:  Li, Daifeng;  Ma, Shengnan;  Xu, Denghui;  Meng, Xiaocao;  Lei, Ningjing   |  收藏  |  浏览/下载：6/0  |  提交时间：2024/03/27 Triple-negative breast cancer  Epidermal growth factor receptor  Peptide-functionalized therapy  Peptide self-assembly  Nanoplatform   Optimization of Brigatinib as New Wild-Type Sparing Inhibitors of EGFR(T790M/C797S) Mutants 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2022, 页码: 7 作者:  Li, Shan;  Zhang, Tao;  Zhu, Su-Jie   |  收藏  |  浏览/下载：25/0  |  提交时间：2022/06/15 Epidermal Growth Factor Receptor (EGFR)  Resistant Mutation  C797S  Antitumor   LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo 期刊论文  OAI收割 CANCER SCIENCE, 2021, 页码: 12 作者:  Liu, Yingqiang;  Lai, Mengzhen;  Li, Shan;  Wang, Yanan;  Feng, Fang   |  收藏  |  浏览/下载：87/0  |  提交时间：2022/01/18 C797S  epidermal growth factor receptor  fourth-generation EGFR TKI  non-small cell lung cancer  osimertinib resistance   Design and synthesis of selective degraders of EGFR(L858R/T790M) mutant 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2020, 卷号: 192, 页码: 14 作者:  Zhang, Xin;  Xu, Fang   |  收藏  |  浏览/下载：68/0  |  提交时间：2020/07/01 Epidermal growth factor receptor (EGFR)  Resistance  Proteolysis targeting chimera (PROTAC)  Protein degradation   Structure-based design and synthesis of 2,4-diaminopyrimidines as EGFR L858R/T790M selective inhibitors for NSCLC 期刊论文  OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2017, 卷号: 140, 页码: 510-527 作者:  Chen, Lingfeng;  Fu, Weitao;  Feng, Chen;  Qu, Rong;  Tong, Linjiang   |  收藏  |  浏览/下载：55/0  |  提交时间：2019/01/08 Epidermal growth factor receptor  Tyrosine kinase inhibitors  Non-small cell lung cancer  T790M  Mutant-selective   Discovery of 5-(methylthio)pyrimidine derivatives as L858R/T790M mutant selective epidermal growth factor receptor (EGFR) inhibitors 期刊论文  OAI收割 BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 卷号: 24, 期号: 12, 页码: 2673-2680 作者:  Xiao, Qiang;  Qu, Rong;  Gao, Dingding;  Yan, Qi;  Tong, Linjiang   |  收藏  |  浏览/下载：23/0  |  提交时间：2019/01/08 5-(Methylthio)pyrimidine derivatives  Mutant selective inhibitors  Epidermal growth factor inhibitor  NSCLC  Structure-based drug design   Design and Synthesis of a Series of Novel Bisquinazoline Glycosides as Epidermal Growth Factor Receptor Inhibitors 期刊论文  OAI收割 CHEMICAL BIOLOGY & DRUG DESIGN, 2011, 卷号: 78, 期号: 6, 页码: 1006-1013 作者:  Chen, Shaopeng;  Zhang, Xiaowei;  Wang, Junlei;  Wan, Shengbiao;  Geng, Meiyu   |  收藏  |  浏览/下载：38/0  |  提交时间：2019/01/08 epidermal growth factor receptor inhibition  glycoside  quinazoline   Clarifying the signal network of salvianolic acid B using proteomic assay and bioinformatic analysis 期刊论文  OAI收割 PROTEOMICS, 2011, 卷号: 11, 期号: 8, 页码: 1473-1485 作者:  Feng, Li-Xing;  Jing, Chun-Jie;  Tang, Kai-Lin;  Tao, Lin;  Cao, Zhi-Wei   |  收藏  |  浏览/下载：13/0  |  提交时间：2019/01/08 2-DE  H9C2 cell  Bioinformatics  Epidermal growth factor receptor  Salvianolic acid B   Adenosine A(1) receptor-mediated transactivation of the EGF receptor produces a neuroprotective effect on cortical neurons in vitro 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2009, 卷号: 30, 期号: 7, 页码: 889-898 作者:  Xie, Ke-qiang;  Zhang, Li-min;  Cao, Yan;  Zhu, Jun;  Feng, Lin-yin   |  收藏  |  浏览/下载：36/0  |  提交时间：2019/01/08 adenosine A(1) receptor  epidermal growth factor receptor  transactivation  Akt  Src kinase  ERK1/2  G(i) protein  metalloprotease  PI3K