中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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Discovery of (S)-N-(2-Amino-4-fluorophenyl)-4-(1-(3-(4-((dimethylamino)methyl)phenyl)-6-oxopyridazin-1(6H)-yl)ethyl)benzamide as Potent Class I Selective HDAC Inhibitor for Oral Anticancer Drug Candidate
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 10, 页码: 7016-7037
作者:
Li, Daqiang
;
Zhang, Zhuo
;
Li, Yalei
;
Wang, Xinyi
;
Zhong, Hanyue
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/10/17
Oral [60]fullerene reduces neuroinflammation to alleviate Parkinson's disease via regulating gut microbiome
期刊论文
OAI收割
THERANOSTICS, 2023, 卷号: 13, 期号: 14, 页码: 4936-4951
作者:
Li, Xue
;
Deng, Ruijun
;
Li, Jie
;
Li, Hui
;
Xu, Zhe
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/08
Oral fullerene
Parkinson's disease
Gut microbiota
Neuroinflammation
Neurodegeneration
Design and synthesis of chromone-nitrogen mustard derivatives and evaluation of anti-breast cancer activity
期刊论文
OAI收割
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 431-444
作者:
Sun, Jianan
;
Mu, Jiahui
;
Wang, Shenglin
;
Jia, Cai
;
Li, Dahong
  |  
收藏
  |  
浏览/下载:33/0
  |  
提交时间:2022/06/15
Chromone
nitrogen mustard
breast cancer
apoptosis
Neuroprotective effects of a lead compound from coral via modulation of the orphan nuclear receptor Nurr1
期刊论文
OAI收割
CNS NEUROSCIENCE & THERAPEUTICS, 2022, 页码: 14
作者:
Su, Jian-Wei
;
Yang, Pei
;
Xing, Mei-Mei
;
Chen, Bao
;
Xie, Xia-Hong
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/04/10
C
elegans
corals-derived compounds
neuroprotection
Nurr1
SH-SY5Y cells
Unravelling the key aroma compounds in the characteristic fragrance of Dendrobium officinale flowers for potential industrial application
期刊论文
OAI收割
PHYTOCHEMISTRY, 2022, 卷号: 200, 页码: 8
作者:
Yang, Yu-Han
;
Zhao, Jie
;
Du, Zhi-Zhi
  |  
收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/07/15
Dendrobium officinale
Orchidaceae
Aroma-active compounds
Solvent-assisted flavor evaporation
Progressive addition test
Aroma profile reconstruction
PEG-Bottlebrush Stabilizer-Based Worm-like Nanocrystal Micelles with Long-Circulating and Controlled Release for Delivery of a BCR-ABL Inhibitor against Chronic Myeloid Leukemia (CML)
期刊论文
OAI收割
PHARMACEUTICS, 2022, 卷号: 14
作者:
Liang, Huamin
;
Zou, Fengming
;
Fu, Liyi
;
Liu, Qingwang
;
Wang, Beilei
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/12/23
drug nanocrystal
stabilizer
micelle
BCR-ABL
chronic myeloid leukemia (CML)
Body centered non-fullerene acceptors substitution on triangular shaped Sub-phthalocyanines (SubPcs) based A-D-A organic solar cells: A step toward new strategies for better performances
期刊论文
OAI收割
OPTICAL AND QUANTUM ELECTRONICS, 2022, 卷号: 54, 期号: 1, 页码: 15
作者:
Abbas, Faheem
;
Ali, Usman
;
Ahmad, Hafiz Muhammad Rizwan
;
Tallat, Aqsa
;
Shehzad, Aamir
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/06/15
Sub-phthalocyanines
Triangular OSCs
Optical properties
Density of states
Transition density matrix
Non-fullerene acceptors
Cyclic Phenylmethylsiloxane Oligomers in Municipal Landfills and Their Elimination Mechanisms in Leachate Treatment Processes
期刊论文
OAI收割
ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2021, 卷号: 55, 期号: 6, 页码: 3756-3764
作者:
Xu, Lin
;
Xu, Shihe
;
Huang, Zichun
;
Xiang, Xiaoling
;
Cai, Yaqi
  |  
收藏
  |  
浏览/下载:4/0
  |  
提交时间:2021/12/22
phenylmethylsiloxanes
landfill leachate
temporal trends
hydroxylation
Glucuronomannan GM2 from Saccharina japonica Enhanced Mitochondrial Function and Autophagy in a Parkinson's Model
期刊论文
OAI收割
MARINE DRUGS, 2021, 卷号: 19, 期号: 2, 页码: 15
作者:
Liu, Yingjuan
;
Jin, Weihua
;
Deng, Zhenzhen
;
Zhang, Quanbin
;
Wang, Jing
  |  
收藏
  |  
浏览/下载:40/0
  |  
提交时间:2021/04/14
glucuronomannan oligosaccharide
Parkinson’
s disease
apoptosis
autophagy
mitochondria
Thymoquinone Prevents Dopaminergic Neurodegeneration by Attenuating Oxidative Stress Via the Nrf2/ARE Pathway
期刊论文
OAI收割
FRONTIERS IN PHARMACOLOGY, 2021, 卷号: 11
作者:
Dong, Jianjian
;
Zhang, Xiaoming
;
Wang, Shijing
;
Xu, Chenchen
;
Gao, Manli
  |  
收藏
  |  
浏览/下载:30/0
  |  
提交时间:2021/03/15
Parkinson's disease
thymoquinone
Nrf2/ARE signaling pathway
oxidative stress
neurodegeneration