中国科学院机构知识库网格系统: 检索

浏览/检索结果: 共5条，第1-5条

帮助

条数/页：排序方式：
	A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir 期刊论文 OAI收割 SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2023, 卷号: 8, 期号: 1, 页码: 10 作者: Zhang, Yumin; Sun, Yuan; Xie, Yuanchao; Shang, Weijuan; Wang, Zhen \| 收藏 \| 浏览/下载：5/0 \| 提交时间：2023/12/08
	Design, synthesis and biological evaluation of peptidomimetic benzothiazolyl ketones as 3CLpro inhibitors against SARS-CoV-2 期刊论文 OAI收割 EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 13 作者: Yang, Hanxi; You, Mengyuan; Shu, Xiaoyang; Zhen, Jingyao; Zhu, Mengwei \| 收藏 \| 浏览/下载：12/0 \| 提交时间：2023/10/17 Peptidomimetics Benzothiazolyl ketone 3CLpro inhibitor Pharmacokinetic properties SARS-CoV-2
	Efficacy and safety of SIM0417 (SSD8432) plus ritonavir for COVID-19 treatment: a randomised, double-blind, placebo- controlled, phase 1b trial 期刊论文 OAI收割 LANCET REGIONAL HEALTH-WESTERN PACIFIC, 2023, 卷号: 38, 页码: 13 作者: Wang, Fuxiang; Xiao, Wen; Tang, Yimin; Cao, Mengli; Shu, Dan \| 收藏 \| 浏览/下载：12/0 \| 提交时间：2023/10/17 Covid-19 3CL protease inhibitor SARS-CoV-2 viral load Alleviation of COVID-19 symptoms
	Discovery and mechanism of action of Thonzonium bromide from an FDA-approved drug library with potent and broad-spectrum inhibitory activity against main proteases of human coronaviruses 期刊论文 OAI收割 BIOORGANIC CHEMISTRY, 2023, 卷号: 130, 页码: 11 作者: Wang, Ruyu; Zhai, Guanglei; Zhu, Guanghao; Wang, Mengge; Gong, Xiaoyi \| 收藏 \| 浏览/下载：12/0 \| 提交时间：2023/04/10 SARS-CoV-23CLpro Thonzonium bromide Mechanism of action Broad-spectrum inhibitor
	Substrate Binding and Homo-Dimerization of SARS 3CL Proteinase are Mutual Allosteric Effectors 期刊论文 OAI收割 ACTA PHYSICO-CHIMICA SINICA, 2010, 卷号: 26, 期号: 4, 页码: 1093-1098 作者: Wei Ping; Li Chun-Mei; Zhou Lu; Liu Ying; Lai Lu-Hua \| 收藏 \| 浏览/下载：19/0 \| 提交时间：2019/04/09 Allosteric Effect Sars 3cl Proteinase Analytical Ultracentrifugation Substrate Enhanced Enzyme Dimenzation