中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [13]
近代物理研究所 [7]
上海生物化学与细胞生... [4]
南海海洋研究所 [3]
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期刊论文 [45]
学位论文 [4]
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Innovative Eco-Friendly Microwave-Assisted Rapid Biosynthesis of Ag/AgCl-NPs Coated with Algae Bloom Extract as Multi-Functional Biomaterials with Non-Toxic Effects on Normal Human Cells
期刊论文
OAI收割
NANOMATERIALS, 2023, 卷号: 13, 期号: 14, 页码: 27
作者:
Pekkoh, Jeeraporn
;
Ruangrit, Khomsan
;
Kaewkod, Thida
;
Tragoolpua, Yingmanee
;
Hoijang, Supawitch
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/13
anticancer
antioxidant
biosynthesis
macroalgae
microwave
silver nanoparticles
Bispecific antibody targeting both B7-H3 and PD-L1 exhibits superior antitumor activities
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 9
作者:
Li, Hua-ying
;
Chen, Yi-li
;
Deng, Xiang-nan
;
Li, Huan-huan
;
Tan, Jie
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2023/10/17
cancer immunotherapy
B7-H3
PD-L1
bispecific antibodies
VHH
antibody-dependent cell-mediated cytotoxicity (ADCC)
Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as novel and potent TBK1 inhibitors: design, synthesis, biological evaluation, and molecular docking study
期刊论文
OAI收割
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1411-1425
作者:
Sun, Yin
;
Tang, Haotian
;
Wang, Xiaoyan
;
Feng, Fang
;
Fan, Tiantian
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/08/16
TBK1 inhibitors
1H-pyrazolo[3
4-b]pyridine
structure-activity relationships (SARs)
immune response
cancer therapy
Synthesis of silver nanoparticles using Eucommia ulmoides extract and their potential biological function in cosmetics
期刊论文
OAI收割
HELIYON, 2022, 卷号: 8
作者:
Xi, Jinfeng
;
Kan, Wenjie
;
Zhu, Yan
;
Huang, Shengwei
;
Wu, Lifang
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2022/12/23
Eucommia ulmoides
AgNPs
Antioxidant activity
Tyrosinase activity
Optimization of the Natural Product Calothrixin A to Discover Novel Dual Topoisomerase I and II Inhibitors with Improved Anticancer Activity
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 11, 页码: 8040-8061
作者:
Yang, Xiaohong
;
Wang, Zhi-Peng
;
Xiang, Sichuan
;
Wang, Daoqiang
;
Zhao, Yi
  |  
收藏
  |  
浏览/下载:22/0
  |  
提交时间:2022/08/22
Structure-Aided Design, Synthesis, and Biological Evaluation of Potent and Selective Non-Nucleoside Inhibitors Targeting Protein Arginine Methyltransferase 5
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 11, 页码: 7854-7875
作者:
Rong, Deqin
;
Zhou, Kaixin
;
Fang, Wei
;
Yang, Hong
;
Zhang, Yi
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2022/08/16
Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 214
作者:
Xu, Biao
;
Wang, Zhi-Peng
;
Liu, Qingwang
;
Yang, Xiaohong
;
Li, Xuemin
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2021/04/26
Pyruvate dehydrogenase kinase
Proliferation
Cancer metabolism
Structure-activity relationship
Synthesis, biological evaluation and structure-activity relationship of novel dichloroacetophenones targeting pyruvate dehydrogenase kinases with potent anticancer activity
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 214, 页码: 16
作者:
Xu, Biao
;
Wang, Zhi-Peng
;
Liu, Qingwang
;
Yang, Xiaohong
;
Li, Xuemin
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2021/05/17
Pyruvate dehydrogenase kinase
Proliferation
Cancer metabolism
Structure-activity relationship
Triterpenoid Saponin and Lignan Glycosides from the Traditional Medicine Elaeagnus angustifolia Flowers and Their Cytotoxic Activities
期刊论文
OAI收割
MOLECULES, 2020, 卷号: 25, 期号: 3, 页码: 1-9
作者:
Han, JX (Han, Jianxin)[ 1,2,3 ]
;
Chen, XY (Chen, Xiaoyu)[ 2,3 ]
;
Liu, W (Liu, Wei)[ 2,3,4 ]
;
Cui, H (Cui, Hao)[ 4 ]
;
Yuan, T (Yuan, Tao)[ 2,3,4 ]
  |  
收藏
  |  
浏览/下载:13/0
  |  
提交时间:2020/03/16
Elaeagnus angustifolia
Elaeagnaceae
triterpenoid saponin
lignans
cytotoxicity
A375
PD-L1 expression levels on tumor cells affect their immunosuppressive activity
期刊论文
OAI收割
ONCOLOGY LETTERS, 2019, 卷号: 18, 期号: 5, 页码: 5399-5407
作者:
Zheng, Yang
;
Fang, You-Chen
;
Li, Jing
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2020/07/01
programmed cell death 1
programmed death-ligand 1
co-culture
immunosuppression
signaling pathway