机构

• 上海生物化学与细胞生... [3]
• 上海营养与健康研究所 [3]
• 上海药物研究所 [2]
• 水生生物研究所 [2]
• 合肥物质科学研究院 [2]
• 动物研究所 [1]
• 更多

采集方式

• OAI收割 [13]

内容类型

• 期刊论文 [12]
• 学位论文 [1]

发表日期

• 2022 [1]
• 2021 [2]
• 2020 [1]
• 2018 [2]
• 2017 [1]
• 2015 [2]
• 更多

学科主题

• Biochemist... [2]
• Cell Biolo... [2]
• Science & ... [2]

筛选

浏览/检索结果: 共13条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 SOMCL-19-133, a novel, selective, and orally available inhibitor of NEDD8-activating enzyme (NAE) for cancer therapy 期刊论文  OAI收割 NEOPLASIA, 2022, 卷号: 32, 页码: 12 作者:  Zhou, Li-Na;  Xiong, Chaodong;  Cheng, Yong-Jun;  Song, Shan-Shan;  Bao, Xu-Bin   |  收藏  |  浏览/下载：14/0  |  提交时间：2023/04/10 SOMCL-19-133  NAE inhibitor  MLN4924  NEDD8  Oral administration   Development of Potent NEDD8-Activating Enzyme Inhibitors Bearing a Pyrimidotriazole Scaffold 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2021, 卷号: 64, 期号: 9, 页码: 6161-6178 作者:  Xiong, Chaodong;  Zhou, Lina;  Tan, Jing;  Song, Shanshan;  Bao, Xubin   |  收藏  |  浏览/下载：19/0  |  提交时间：2021/08/17 Targeting Protein Neddylation to Inactivate Cullin-RING Ligases by Gossypol: A Lucky Hit or a New Start? 期刊论文  OAI收割 DRUG DESIGN DEVELOPMENT AND THERAPY, 2021, 卷号: 15 作者:  Yu, Qing;  Sun, Yi   |  收藏  |  浏览/下载：26/0  |  提交时间：2021/03/15 anti-cancer drug  cullin-RING E3 ligases  natural product  high-throughput screen  neddylation  small-molecule inhibitors   Zebrafish Nedd8 facilitates ovarian development and the maintenance of female secondary sexual characteristics via suppression of androgen receptor activity 期刊论文  OAI收割 DEVELOPMENT, 2020, 卷号: 147, 期号: 18, 页码: 14 作者:  Yu, Guangqing;  Liu, Xing;  Zhang, Dawei;  Wang, Jing;  Ouyang, Gang   |  收藏  |  浏览/下载：21/0  |  提交时间：2020/12/03 Nedd8  Zebrafish  Androgen receptor  Ovary  Testis  Neddylation   Inhibition of neddylation by MLN4924 improves neointimal hyperplasia and promotes apoptosis of vascular smooth muscle cells through p53 and p62 期刊论文  OAI收割 CELL DEATH AND DIFFERENTIATION, 2018, 卷号: 25, 期号: 2, 页码: 319-329 作者:  Ai, Tang-Jun;  Sun, Jian-Yong;  Du, Lin-Juan;  Shi, Chaoji;  Li, Chao   |  收藏  |  浏览/下载：17/0  |  提交时间：2020/12/09 HSP90 beta  lipid metabolism  corylin  SREBPs  proteasomal degradation   Quantitative integration of epigenomic variation and transcription factor binding using MAmotif toolkit identifies an important role of IRF2 as transcription activator at gene promoters 期刊论文  OAI收割 CELL DISCOVERY, 2018, 卷号: 4, 期号: -, 页码: 38 作者:  Sun, Hongduo;  Gong, Zhaohui;  Yao, Jiaying;  Wang, Yuangao;  Shao, Zhen   |  收藏  |  浏览/下载：17/0  |  提交时间：2020/12/09 Circadian rhythm  Rhythmically expressed gene  Rhythmic gene function  Energy cost   The Protein Neddylation Pathway in Trypanosoma brucei FUNCTIONAL CHARACTERIZATION AND SUBSTRATE IDENTIFICATION 期刊论文  OAI收割 JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 卷号: 292, 期号: 3, 页码: 1081-+ 作者:  Liao, Shanhui;  Hu, Huiqing;  Wang, Tao;  Tu, Xiaoming;  Li, Ziyin   |  收藏  |  浏览/下载：27/0  |  提交时间：2018/07/04 NEDD8-Mediated Neddylation Is Required for Human Endometrial Stromal Proliferation and Decidualization 期刊论文  OAI收割 Human Reproduction, 2015, 卷号: 30, 期号: 7, 页码: 1665-1676 作者:  Yi-Xin Liao;  Jiang YL(蒋亚玲);  Hui He;  Hao Ni;  Tu ZW(涂兆伟)   |  收藏  |  浏览/下载：9/0  |  提交时间：2016/06/14 The Neddylation-Cullin 2-RBX1 E3 Ligase Axis Targets Tumor Suppressor RhoB for Degradation in Liver Cancer 期刊论文  OAI收割 MOLECULAR & CELLULAR PROTEOMICS, 2015, 卷号: 14, 期号: 3, 页码: 499-509 作者:  Xu, Junfeng;  Li, Lihui;  Yu, Guangyang;  Ying, Wantao;  Gao, Qiang 收藏  |  浏览/下载：26/0  |  提交时间：2015/09/02 Aggregation of polyglutamine-expanded ataxin-3 sequesters its specific interacting partners into inclusions: Implication in a loss-of-function pathology 期刊论文  OAI收割 SCIENTIFIC REPORTS, 2014, 卷号: 4, 期号: 1, 页码: 6410-6410 作者:  Yang, H;  Li, JJ;  Liu, S;  Zhao, J;  Jiang, YJ 收藏  |  浏览/下载：37/0  |  提交时间：2015/07/22