中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [53]
上海生物化学与细胞... [32]
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Tail engagement of arrestin at the glucagon receptor
期刊论文
OAI收割
NATURE, 2023, 页码: 21
作者:
Chen, Kun
;
Zhang, Chenhui
;
Lin, Shuling
;
Yan, Xinyu
;
Cai, Heng
  |  
收藏
  |  
浏览/下载:15/0
  |  
提交时间:2023/10/17
GPCR activation and GRK2 assembly by a biased intracellular agonist
期刊论文
OAI收割
NATURE, 2023, 页码: 27
作者:
Duan, Jia
;
Liu, Heng
;
Zhao, Fenghui
;
Yuan, Qingning
;
Ji, Yujie
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Conserved class B GPCR activation by a biased intracellular agonist
期刊论文
OAI收割
NATURE, 2023, 页码: 25
作者:
Zhao, Li-Hua
;
He, Qian
;
Yuan, Qingning
;
Gu, Yimin
;
He, Xinheng
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/10/17
The ketone body acetoacetate activates human neutrophils through FFAR2
期刊论文
OAI收割
JOURNAL OF LEUKOCYTE BIOLOGY, 2023, 卷号: 113, 期号: 6, 页码: 577-587
作者:
Martensson, Jonas
;
Bjorkman, Lena
;
Lind, Simon
;
Viklund, Moa Bjerhem
;
Zhang, Linjie
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
acetoacetate
FFAR2
G-protein coupled receptor
ketone body
neutrophil
Molecular recognition of morphine and fentanyl by the human mu-opioid receptor
期刊论文
OAI收割
CELL, 2022, 卷号: 185, 期号: 23, 页码: 4361-+
作者:
Zhuang, Youwen
;
Wang, Yue
;
He, Bingqing
;
He, Xinheng
;
Zhou, X. Edward
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收藏
  |  
浏览/下载:14/0
  |  
提交时间:2023/04/10
Recent progress in assays for GPCR drug discovery
期刊论文
OAI收割
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2022, 卷号: 323, 期号: 2, 页码: C583-C594
作者:
Guo, Shimeng
;
Zhao, Tingting
;
Yun, Ying
;
Xie, Xin
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2023/04/10
biased signaling
GPCR
high -throughput screening assays
humanized mouse model
protein
protein interaction
Computational characterization of transducer recognition of 132 adrenergic receptor
期刊论文
OAI收割
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2022, 卷号: 592, 页码: 67-73
作者:
Zhao, Lifen
;
He, Xinheng
;
Jiang, Hualiang
;
Cheng, Xi
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收藏
  |  
浏览/下载:20/0
  |  
提交时间:2022/06/15
Class A G-protein coupled receptor
Coupling selectivity
Transducer-binding interface
Functional signal
Complex models
Modulating effects of RAMPs on signaling profiles of the glucagon receptor family
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 2, 页码: 637-650
作者:
Shao, Lijun
;
Chen, Yan
;
Zhang, Shikai
;
Zhang, Zhihui
;
Cao, Yongbing
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收藏
  |  
浏览/下载:23/0
  |  
提交时间:2022/06/15
G protein-coupled receptor
Glucagon receptor family
Receptor activity-modulating protein
Signaling
Allosteric modulation
GPCR-RAMP interaction
Receptor pharmacology
Ligand selectivity
Humans have used opioids to suppress moderate to severe pain for thousands of years. However, the long-term use of opioids has several adverse effects, such as opioid tolerance, opioid-induced hyperal
期刊论文
OAI收割
International Journal of Environmental Research and Public Health, 2022, 卷号: 19, 期号: 4, 页码: 11
作者:
Wang, Xiaqing
;
Bao, Chongyu
;
Li, Zhenjiang
;
Yue, Lupeng
;
Hu, Li
  |  
收藏
  |  
浏览/下载:29/0
  |  
提交时间:2022/04/02
Side Effects of Opioids Are Ameliorated by Regulating TRPV1 Receptors
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2022, 卷号: 19, 期号: 4, 页码: 11
作者:
Xiaqing Wang
;
Chongyu Bao
;
Zhenjiang Li
;
Lupeng Yue
;
Li Hu
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/04/02
TRPV1
µ-opioid
opioid side effects
neuropathic pain
β-arrestin2