中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [84]
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The promise and challenges of combination therapies with antibody-drug conjugates in solid tumors
期刊论文
OAI收割
JOURNAL OF HEMATOLOGY & ONCOLOGY, 2024, 卷号: 17, 期号: 1, 页码: 32
作者:
Wei, Qing
;
Li, Peijing
;
Yang, Teng
;
Zhu, Jiayu
;
Sun, Lu
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2024/02/27
Antibody-drug conjugate
Solid tumor
Combination therapy
Immunotherapy
Targeted therapy
Co-delivering irinotecan and imiquimod by pH-responsive micelle amplifies anti-tumor immunity against colorectal cancer
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2023, 卷号: 648, 页码: 14
作者:
Yan, Wenlu
;
Li, Yu
;
Zou, Yiting
;
Zhu, Runqi
;
Wu, Ting
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2024/01/16
Colorectal cancer
Irinotecan
Imiquimod
Micelle
Immune response
Oral Delivery of Gemcitabine-Loaded Glycocholic Acid-Modified Micelles for Cancer Therapy
期刊论文
OAI收割
ACS NANO, 2023, 卷号: 17, 期号: 18, 页码: 18074-18088
作者:
Zang, Wenqing
;
Gao, Duo
;
Yu, Miaorong
;
Long, Manmei
;
Zhang, Zhuan
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
oral delivery
gemcitabine
micelles
glycocholic acid
chemotherapy
Chloroquine enhances the efficacy of chemotherapy drugs against acute myeloid leukemia by inactivating the autophagy pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2023, 页码: 11
作者:
Wang, Han-lin
;
Li, Jia-nan
;
Kan, Wei-juan
;
Xu, Gao-ya
;
Luo, Guang-hao
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2023/10/17
acute myeloid leukemia
cytarabine
daunorubicin
idarubicin
drug resistant
multi-omics
autophagy
chloroquine phosphate
Targeting lactate metabolism and immune interaction in breast tumor via protease-triggered delivery
期刊论文
OAI收割
JOURNAL OF CONTROLLED RELEASE, 2023, 卷号: 358, 页码: 706-717
作者:
Zhao, Pengfei
;
Wang, Shuang
;
Jiang, Jizong
;
Gao, Yanrong
;
Wang, Yuewei
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Legumain
Lactate
Tumor immune microenvironment (TIME)
Quercetin
Immunometabolism
Modular Biomimetic Strategy Enabled Discovery of Simplified Pseudo-Natural Macrocyclic P-Glycoprotein Inhibitors Capable of Overcoming Multidrug Resistance
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 4, 页码: 2550-2565
作者:
Liu, Bo
;
Yu, Xueni
;
Liu, Liping
;
Wang, Lei
;
Wang, Jie
  |  
收藏
  |  
浏览/下载:2/0
  |  
提交时间:2024/03/27
Design, synthesis of novel benzimidazole derivatives as ENL inhibitors suppressing leukemia cells viability via downregulating the expression of MYC
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 14
作者:
Guo, Siqi
;
Jia, Tongguan
;
Xu, Xiaoming
;
Yang, Feng
;
Xiao, Senhao
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2023/04/10
ENL Inhibitor
YEATS domain
Histone lysine acetylation
Benzimidazole derivatives
Acute myeloid leukemia
Development of a series of quinazoline-2,5-diamine derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 248, 页码: 20
作者:
Shi, Huanyu
;
Tang, Haotian
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/04/10
Cancer immunotherapy
SAR study
HPK1 inhibitors
Quinazoline-2
5-diamine
IL-2 production
Rare sugar l-sorbose exerts antitumor activity by impairing glucose metabolism
期刊论文
OAI收割
COMMUNICATIONS BIOLOGY, 2023, 卷号: 6, 期号: 1
作者:
Xu, HuiLin
;
Zhou, Xiaoman
;
Chen, Shuai
;
Xu, Si
;
Li, Zijie
  |  
收藏
  |  
浏览/下载:0/0
  |  
提交时间:2023/05/22
Proteomics Analysis Revealed Smad3 as a Potential Target of the Synergistic Anti-tumor Activity of Disulfiram and Cisplatin in Ovarian Cancer
期刊论文
OAI收割
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, 2023, 卷号: 23
作者:
Du, Ruiping
;
Sun, Feilong
;
Li, Kai
;
Qi, Jian
;
Zhong, Wen
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/11/10
Disulfiram
cisplatin resistance
ovarian cancer
proteomics analysis
SMAD3
lactate dehydrogenase