中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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上海药物研究所 [251]
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Design and synthesis of cantharidin derivative DCZ5418 as a TRIP13 inhibitor with anti-multiple myeloma activity
in
vitro
and
in
vivo
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2024, 卷号: 98, 页码: 7
作者:
Dong, Sanfeng
;
Hu, Ke
;
Shi, Yulong
;
Wang, Guanli
;
Yu, Dandan
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/02/19
Multiple myeloma
TRIP13 inhibitor
Cantharidin
DCZ5418
DCZ0415
How iron-bearing minerals affect the biological reduction of Sb(V): A newly discovered function of nitrate reductase
期刊论文
OAI收割
SCIENCE OF THE TOTAL ENVIRONMENT, 2023, 卷号: 904, 页码: 11
作者:
Zhang, Haikun
;
Sun, Yanyu
;
Cheng, Manman
;
Sui, Xiaori
;
Huang, Yanyan
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2023/11/15
Antimony
Iron-bearing minerals
Biological reduction
Nitrate reductase
Inhibition
Discovery of Dual Function Agents That Exhibit Anticancer Activity via Catastrophic Nicotinamide Adenine Dinucleotide Depletion
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 24, 页码: 16694-16703
作者:
Fu, Yixian
;
Huang, Yahui
;
Zhou, Chenchen
;
Li, Xinge
;
Dong, Guoqiang
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2024/01/26
Molecular characteristics of
IGF
and
IGF1R
genes and their potential roles on longevity in two scallops with distinct lifespans
期刊论文
OAI收割
AQUACULTURE REPORTS, 2023, 卷号: 33, 页码: 14
作者:
Wang, Yuan
;
Wang, Chunde
;
Ning, Junhao
;
Yu, Tieying
;
Yuan, Ke
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2024/01/26
Argopecten scallops
IGF
IGF1R
Longevity
Gene expression
Nutrition restriction
Ionizing radiation
Chemical Inhibitors Targeting the Oncogenic m
6
A Modifying Proteins
期刊论文
OAI收割
ACCOUNTS OF CHEMICAL RESEARCH, 2023, 卷号: 56, 期号: 21, 页码: 3010-3022
作者:
Huang, Yue
;
Xia, Wenyang
;
Dong, Ze
;
Yang, Cai-Guang
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/11
The Molecular Basis of Catalysis by SDR Family Members Ketoacyl-ACP Reductase FabG and Enoyl-ACP Reductase FabI in Type-II Fatty Acid Biosynthesis
期刊论文
OAI收割
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2023, 页码: 12
作者:
Zhou, Jiashen
;
Zhang, Lin
;
Wang, Yiran
;
Song, Wenyan
;
Huang, Yuzhou
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/12/08
Acyl-ACP Reductases
Allosteric Regulation
Biosynthesis
Enantioselective Reduction
Enzyme Catalysis
Effects of exposure to nanoplastics on the gill of mussels
Mytilus
galloprovincialis:
An integrated perspective from multiple biomarkers
期刊论文
OAI收割
MARINE ENVIRONMENTAL RESEARCH, 2023, 卷号: 191, 页码: 8
作者:
Wang, Xin
;
Shao, Shengyuan
;
Zhang, Tianyu
;
Zhang, Qianqian
;
Yang, Dinglong
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/11/15
Nanoplastics
Nanotoxicology
Biomarkers
Invertebrates
Ecotoxicology
Design, synthesis and biological evaluation of peptidomimetic benzothiazolyl ketones as 3CLpro inhibitors against SARS-CoV-2
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 257, 页码: 13
作者:
Yang, Hanxi
;
You, Mengyuan
;
Shu, Xiaoyang
;
Zhen, Jingyao
;
Zhu, Mengwei
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Peptidomimetics
Benzothiazolyl ketone
3CLpro inhibitor
Pharmacokinetic properties
SARS-CoV-2
Response of soybean and maize roots and soil enzyme activities to biodegradable microplastics contaminated soil
期刊论文
OAI收割
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 2023, 卷号: 262, 页码: 10
作者:
Yu, Yao
;
Chen, Yanhua
;
Wang, Yan
;
Xue, Sha
;
Liu, Mengjuan
  |  
收藏
  |  
浏览/下载:62/0
  |  
提交时间:2023/10/09
Biodegradable plastic
Microplastics
Plant root
Enzyme activities
Design, synthesis and biological evaluation of salicylanilides as novel allosteric inhibitors of human pancreatic lipase
期刊论文
OAI收割
BIOORGANIC & MEDICINAL CHEMISTRY, 2023, 卷号: 91, 页码: 11
作者:
Zhao, Yitian
;
Zhang, Min
;
Hou, Xudong
;
Han, Jiaxin
;
Qin, Xiaoya
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2023/10/17
Salicylanilide
hPL inhibitor
Structure -activity relationship
Anti -obesity