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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
机构
上海药物研究所 [7]
西北高原生物研究所 [1]
新疆理化技术研究所 [1]
心理研究所 [1]
海洋研究所 [1]
合肥物质科学研究院 [1]
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OAI收割 [12]
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期刊论文 [12]
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2023 [1]
2022 [1]
2020 [2]
2019 [1]
2018 [1]
2017 [3]
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Hypoglycemic effect of Nitraria tangutorum fruit by inhibiting glycosidase and regulating IRS1/PI3K/AKT signalling pathway and its active ingredient identification by UPLC-MS
期刊论文
OAI收割
FOOD & FUNCTION, 2023, 卷号: 14, 期号: 17, 页码: 7869
作者:
Jiang, Sirong
;
Wang, Luya
;
Jia, Wenjing
;
Wu, Di
;
Wu, Li
  |  
收藏
  |  
浏览/下载:5/0
  |  
提交时间:2023/12/01
Nrf2-mediated liver protection by 18 beta-glycyrrhetinic acid against pyrrolizidine alkaloid-induced toxicity through PI3K/Akt/GSK3 beta pathway
期刊论文
OAI收割
PHYTOMEDICINE, 2022, 卷号: 102, 页码: 12
作者:
Wang, Zhangting
;
Ma, Jiang
;
He, Yisheng
;
Miu, Kai-Kei
;
Yao, Sheng
  |  
收藏
  |  
浏览/下载:47/0
  |  
提交时间:2022/08/30
Pyrrolizidine alkaloids
Herb-induced liver injury
18 beta-glycyrrhetinic acid
Liquorice
Nuclear factor erythroid-2-related factor 2
PI3K/Akt/GSK3 beta
Development of Bisindole-Substituted Aminopyrazoles as Novel GSK-3 beta Inhibitors with Suppressive Effects against Microglial Inflammation and Oxidative Neurotoxicity
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2020, 卷号: 11, 期号: 20, 页码: 3398-3408
作者:
Liu, Jian-Guo
;
Zhao, Danfeng
;
Gong, Qi
;
Bao, Fengxia
;
Chen, Wen-Wen
  |  
收藏
  |  
浏览/下载:10/0
  |  
提交时间:2021/05/24
Glycogen synthase kinase-3
bisindole-substituted aminopyrazoles
Alzheimer's disease
oxidative neurotoxicity
microglial inflammation
Gandou decoction, a Chinese medicinal formula, in the treatment of hepatic injury by Wnt/beta-catenin pathway regulation in models of Wilson disease
期刊论文
OAI收割
ANNALS OF PALLIATIVE MEDICINE, 2020, 卷号: 9
作者:
Gao, Manli
;
Geng, Hao
;
Wu, Peng
;
Dong, Jianjian
;
Li, Hai
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2020/11/30
Wilson disease (WD)
liver injury
Gandou decoction (GDD)
Wnt/beta-catenin pathway
oxidative stress
Ribosylation-Derived Advanced Glycation End Products Induce Tau Hyperphosphorylation Through Brain-Derived Neurotrophic Factor Reduction
期刊论文
OAI收割
JOURNAL OF ALZHEIMERS DISEASE, 2019, 卷号: 71, 期号: 1, 页码: 291-305
作者:
Wu, Beibei
;
Wang, Yujing
;
Shi, Chenggang
;
Chen, Yao
;
Yu, Lexiang
  |  
收藏
  |  
浏览/下载:65/0
  |  
提交时间:2019/10/25
Advanced glycation end products
brain-derived neurotrophic factor
GSK-3 beta oxidative stress
ribosylation
tau hyperphosphorylation
Design, synthesis and biological evaluation of LX2343 derivatives as neuroprotective agents for the treatment of Alzheimer's disease
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2018, 卷号: 145, 页码: 622-633
作者:
Sun, Guanglong
;
Wang, Junwei
;
Guo, Xiaodan
  |  
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2019/01/08
LX2343 derivatives
Neuroprotective agents
Alzheimer's disease
Structural modifications
Structure-activity relationships
LX2343 alleviates cognitive impairments in AD model rats by inhibiting oxidative stress-induced neuronal apoptosis and tauopathy
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2017, 卷号: 38, 期号: 8, 页码: 1104-1119
作者:
Guo, Xiao-dan
;
Sun, Guang-long
;
Zhou, Ting-ting
;
Wang, Yi-yang
;
Xu, Xin
  |  
收藏
  |  
浏览/下载:36/0
  |  
提交时间:2019/01/08
Alzheimer's disease
LX2343
cognitive deficits
oxidative stress
tauopathy
mitochondria
GSK-3 beta inhibitor
neuroprotection
ICV-STZ rats
Sulfated Hetero-Polysaccharides Protect SH-SY5Y Cells from H2O2-Induced Apoptosis by Affecting the PI3K/Akt Signaling Pathway
期刊论文
OAI收割
MARINE DRUGS, 2017, 卷号: 15, 期号: 4
作者:
Wang, Jing
;
Liu, Huaide
;
Zhang, Xuan
;
Li, Xinpeng
;
Geng, Lihua
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2017/10/09
Sulfated Hetero-polysaccharides
Pi3k/akt
Phosphorylate
Sh-sy5y
Oxidative Stress
Hypoglycemic effect of the polyphenols rich extract from Rose rugosa Thunb on high fat diet and STZ induced diabetic rats
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2017, 卷号: 200, 期号: 3, 页码: 174-181
作者:
Liu, L (Liu, Liu)
;
Tang, D (Tang, Dan)
;
Zhao, HQ (Zhao, Haiqing)
;
Xin, XL (Xin, Xuelei)
;
Aisa, HA (Aisa, Haji Akber)
收藏
  |  
浏览/下载:26/0
  |  
提交时间:2017/05/19
Rose rugosa Thunb
Diabetes
Antioxidant
PI3K/AKT signaling pathway
A novel GSK-3 beta inhibitor YQ138 prevents neuronal injury induced by glutamate and brain ischemia through activation of the Nrf2 signaling pathway
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 6, 页码: 741-752
作者:
Pang, Tao
;
Wang, Yun-jie
;
Gao, Yuan-xue
;
Xu, Yuan
;
Li, Qiu
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2019/01/08
GSK-3 beta inhibitor
YQ138
cerebellar granule cells
glutamate excitotoxicity
OGD
middle cerebral artery occlusion
brain ischemia
neuroprotection
Nrf2