中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [16]
上海营养与健康研究所 [5]
武汉物理与数学研究所 [2]
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期刊论文 [29]
学位论文 [2]
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2022 [6]
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Ligand-switchable nanoparticles resembling viral surface for sequential drug delivery and improved oral insulin therapy
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 16
作者:
Yang, Tiantian
;
Wang, Aohua
;
Nie, Di
;
Fan, Weiwei
;
Jiang, Xiaohe
  |  
收藏
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浏览/下载:12/0
  |  
提交时间:2023/04/10
An emerging direction in glucagon-based therapy
期刊论文
OAI收割
CELL METABOLISM, 2022, 卷号: 34, 期号: 11, 页码: 1615-1616
作者:
Chen, Yan
;
Yang, Dehua
;
Wang, Ming-Wei
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/04/10
Hepatic thyroid hormone signalling modulates glucose homeostasis through the regulation of GLP-1 production via bile acid-mediated FXR antagonism
期刊论文
OAI收割
NATURE COMMUNICATIONS, 2022, 卷号: 13, 期号: 1, 页码: 16
作者:
Yan, Ying
;
Niu, Zhoumin
;
Sun, Chao
;
Li, Peng
;
Shen, Siyi
  |  
收藏
  |  
浏览/下载:28/0
  |  
提交时间:2022/12/13
Hepatic Sam68 Regulates Systemic Glucose Homeostasis and Insulin Sensitivity
期刊论文
OAI收割
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2022, 卷号: 23, 期号: 19, 页码: 14
作者:
Qiao, Aijun
;
Ma, Wenxia
;
Jiang, Ying
;
Han, Chaoshan
;
Yan, Baolong
  |  
收藏
  |  
浏览/下载:27/0
  |  
提交时间:2022/11/11
Sam68
hepatocytes
gluconeogenesis
high-fat diet
diabetes
CRTC2
insulin sensitivity
glucagon
glucose metabolism
protein-protein interaction
Coronarin A modulated hepatic glycogen synthesis and gluconeogenesis via inhibiting mTORC1/S6K1 signaling and ameliorated glucose homeostasis of diabetic mice
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 14
作者:
Huang, Su-Ling
;
Xie, Wei
;
Ye, Yang-Liang
;
Liu, Jia
;
Qu, Hui
  |  
收藏
  |  
浏览/下载:35/0
  |  
提交时间:2022/11/11
type 2 diabetes mellitus
coronarin A
glycogen synthesis
gluconeogenesis
mTORC1
IRS1
Double-edge sword roles of iron in driving energy production versus instigating ferroptosis
期刊论文
OAI收割
CELL DEATH & DISEASE, 2022, 卷号: 13, 期号: 1, 页码: 40
作者:
Zhang, Shuping
;
Xin, Wei
;
Anderson, Gregory J.
;
Li, Ruibin
;
Gao, Ling
  |  
收藏
  |  
浏览/下载:12/0
  |  
提交时间:2022/11/08
HEPATIC GLUCOSE-PRODUCTION
FATTY-ACID OXIDATION
CELL-DEATH
PARKINSONS-DISEASE
DIABETES-MELLITUS
METABOLISM
TUMOR
MITOCHONDRIA
HOMEOSTASIS
DEFICIENCY
Determination of the antidiabetic chemical basis of Phellodendri Chinensis Cortex by integrating hepatic disposition in vivo and hepatic gluconeogenese inhibition in vitro
期刊论文
OAI收割
JOURNAL OF ETHNOPHARMACOLOGY, 2020, 卷号: 263, 页码: 10
作者:
Tian, Xiaoting
;
Xu, Zhou
;
Hu, Pei
;
Yu, Yanyan
;
Li, Zhixiong
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收藏
  |  
浏览/下载:31/0
  |  
提交时间:2020/12/21
Phellodendri Chinensis cortex
Hepatic disposition
Pharmacokinetics
Berberine
Metabolites
Hepatic gluconeogenesis
Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels
期刊论文
OAI收割
JOURNAL OF BIOLOGICAL CHEMISTRY, 2020, 卷号: 295, 期号: 31, 页码: 10842-10856
作者:
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收藏
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浏览/下载:86/0
  |  
提交时间:2020/12/24
Src homology 2 domain containing tyrosine phosphatase-2 (SHP2)
hepatic steatosis
insulin resistance
caspase-1
interleukin 18 (IL-18)
fatty liver
metabolic disorder
inflammation
cytokine signaling
caspase 1 (CASP1)
tyrosine-protein phosphatase (tyrosine phosphatase)
macrophage
Exploring the Impact of a Low-Protein High-Carbohydrate Diet in Mature Broodstock of a Glucose-Intolerant Teleost, the Rainbow Trout
期刊论文
OAI收割
FRONTIERS IN PHYSIOLOGY, 2020, 卷号: 11, 页码: 21
作者:
Callet, Therese
;
Hu, Huihua
;
Larroquet, Laurence
;
Surget, Anne
;
Liu, Jingwei
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收藏
  |  
浏览/下载:23/0
  |  
提交时间:2020/09/14
liver
gonad
enzymatic activity
glucose metabolism
pentose phosphate pathway
glycogen
male
female
Liver-Target and Glucose-Responsive Polymersomes toward Mimicking Endogenous Insulin Secretion with Improved Hepatic Glucose Utilization
期刊论文
OAI收割
ADVANCED FUNCTIONAL MATERIALS, 2020, 页码: 15
作者:
Wang, Aohua
;
Fan, Weiwei
;
Yang, Tiantian
;
He, Shufang
;
Yang, Yiwei
  |  
收藏
  |  
浏览/下载:51/0
  |  
提交时间:2020/07/01
glucose responsive
insulin secretion
liver target
oral drug delivery
polymersomes