中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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The Effects of Topiramate on Ethanol-Cocaine Interactions andDNA Methyltransferase Gene Expression in the Rat Prefrontal Cortex
期刊论文
OAI收割
出版物, 3111, 期号: 0, 页码: 1-39
作者:
V.Echeverry-Alzate
;
E. Gine
;
K. M. Bühler
;
J. Calleja-Conde
;
P. Olmos
  |  
收藏
  |  
浏览/下载:327/0
  |  
提交时间:2017/07/24
Operant Ethanol Self-administration
Dnmt1 Corepressors
Histone deacetylase-2
Dual Dependence
Dna Methyltransferases
Addiction
Gene Expression
A proteomic landscape of pharmacologic perturbations for functional relevance
期刊论文
OAI收割
JOURNAL OF PHARMACEUTICAL ANALYSIS, 2024, 卷号: 14, 期号: 1, 页码: 128-139
作者:
Liu, Zhiwei
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/04/09
Proteomics
Drug
Perturbation
Drug target
Drug combination
Discovery, Structure-Activity Relationship and In Vitro Anticancer Activity of Small-Molecule Inhibitors of the Protein-Protein Interactions between AF9/ENL and AF4 or DOT1L
期刊论文
OAI收割
CANCERS, 2023, 卷号: 15, 期号: 21, 页码: 28
作者:
Li, Xin
;
Wu, Xiaowei
;
Nie, Shenyou
;
Zhao, Jidong
;
Yao, Yuan
  |  
收藏
  |  
浏览/下载:7/0
  |  
提交时间:2023/12/19
MLL-rearranged leukemia
super elongation complexes
small-molecule inhibitor
protein-protein interaction
cancer therapeutics
Glutamine Production by Glul Promotes Thermogenic Adipocyte Differentiation Through Prdm9-Mediated H3K4me3 and Transcriptional Reprogramming
期刊论文
OAI收割
DIABETES, 2023, 卷号: 72, 期号: 11, 页码: 24
作者:
Pan, Xiaowen
;
Ye, Lingxia
;
Guo, Xiaozhen
;
Wang, Weihua
;
Zhang, Ziyin
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收藏
  |  
浏览/下载:12/0
  |  
提交时间:2024/03/25
Chemical Inhibitors Targeting the Oncogenic m
6
A Modifying Proteins
期刊论文
OAI收割
ACCOUNTS OF CHEMICAL RESEARCH, 2023, 卷号: 56, 期号: 21, 页码: 3010-3022
作者:
Huang, Yue
;
Xia, Wenyang
;
Dong, Ze
;
Yang, Cai-Guang
  |  
收藏
  |  
浏览/下载:6/0
  |  
提交时间:2023/12/11
Structural Modification and Pharmacological Evaluation of Substituted Quinoline-5,8-diones as Potent NSD2 Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 页码: 18
作者:
Tang, Hairong
;
Yu, Aisong
;
Xing, Li
;
Chen, Xiaoyu
;
Ding, Huaqian
  |  
收藏
  |  
浏览/下载:16/0
  |  
提交时间:2023/04/10
Matrix stiffness exacerbates the proinflammatory responses of vascular smooth muscle cell through the DDR1-DNMT1 mechanotransduction axis
期刊论文
OAI收割
BIOACTIVE MATERIALS, 2022, 卷号: 17, 页码: 406-424
作者:
Wang, Jin
;
Xie, Si-an
;
Li, Ning
;
Zhang, Tao
;
Yao, Weijuan
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收藏
  |  
浏览/下载:36/0
  |  
提交时间:2022/06/10
Matrix stiffness
Inflammation
DDR1
DNMT1
Mechanotransduction
Discovery of a potent and selective proteolysis targeting chimera (PROTAC) degrader of NSD3 histone methyltransferase
期刊论文
OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 239, 页码: 18
作者:
Sun, Yaoliang
;
Zhang, Ying
;
Chen, Xiaoai
;
Yu, Aisong
;
Du, Wenhao
  |  
收藏
  |  
浏览/下载:41/0
  |  
提交时间:2022/08/30
NSD3
PROTAC
Degrader
Methyltransferase
Regulation of CCL2 by EZH2 affects tumor-associated macrophages polarization and infiltration in breast cancer
期刊论文
OAI收割
CELL DEATH & DISEASE, 2022, 卷号: 13, 期号: 8, 页码: 15
作者:
Wang, Ya-fang
;
Yu, Lei
;
Hu, Zong-long
;
Fang, Yan-fen
;
Shen, Yan-yan
  |  
收藏
  |  
浏览/下载:18/0
  |  
提交时间:2022/11/11
Structure-Based of a Series of NSD2-PWWP1 Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 13, 页码: 9459-9477
作者:
Li, Na
;
Yang, Hong
;
Liu, Ke
;
Zhou, Liwei
;
Huang, Yuting
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/03/21