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Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [20]
合肥物质科学研究院 [15]
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OAI收割 [46]
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期刊论文 [45]
专著章节 [1]
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2023 [5]
2022 [15]
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Preclinical and early clinical studies of a novel compound SYHA1813 that efficiently crosses the blood-brain barrier and exhibits potent activity against glioblastoma
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2023, 卷号: 13, 期号: 12, 页码: 4748-4764
作者:
Liu, Yingqiang
;
Zhan, Zhengsheng
;
Kang, Zhuang
;
Li, Mengyuan
;
Lv, Yongcong
  |  
收藏
  |  
浏览/下载:9/0
  |  
提交时间:2024/01/26
Small molecule inhibitor
Tumor microenvironment
Immune-checkpoint
immune-deficient mouse models
including temozolomide (TMZ) insensitive tumors. Notably
Design and synthesis of 1H-pyrazolo[3,4-
d
]pyrimidine derivatives as hematopoietic progenitor kinase 1 (HPK1) inhibitors
期刊论文
OAI收割
BIOORGANIC CHEMISTRY, 2023, 卷号: 140, 页码: 18
作者:
Zhang, Junjie
;
Li, Yan
;
Tang, Haotian
;
Zhou, Qianqian
;
Tong, Linjiang
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
Cancer immunotherapy
HPK1
Structure -based design
HPK1 inhibitor
Breaking Tumor Immunosuppressive Network by Regulating Multiple Nodes with Triadic Drug Delivery Nanoparticles
期刊论文
OAI收割
ACS NANO, 2023, 卷号: 17, 期号: 18, 页码: 17826-17844
作者:
Yan, Wenlu
;
Li, Yu
;
Zou, Yiting
;
Zhu, Runqi
;
Wu, Ting
  |  
收藏
  |  
浏览/下载:8/0
  |  
提交时间:2023/12/08
triple-negative breast cancer
antitumor immunity
tumor-associated macrophages
myeloid-derived suppressorcells
immune network
nanoparticle
Aurora A kinase inhibition compromises its antitumor efficacy by elevating PD-L1 expression
期刊论文
OAI收割
JOURNAL OF CLINICAL INVESTIGATION, 2023, 卷号: 133, 期号: 9, 页码: 12
作者:
Wang, Xiaobo
;
Huang, Jing
;
Liu, Fenglin
;
Yu, Qian
;
Wang, Ruina
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2023/10/17
Combined Use of Immune Checkpoint Inhibitors and Phytochemicals as a Novel Therapeutic Strategy against Cancer
期刊论文
OAI收割
JOURNAL OF CANCER, 2023, 卷号: 14, 期号: 12, 页码: 2315-2328
作者:
Luo, LingJie
;
Lin, Caiji
;
Wang, Pengfei
;
Cao, Danli
;
Lin, Yiru
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/10/17
Immune checkpoint inhibitor
Phytochemicals
Combination therapy
Immune-related adverse events
Predictive biomarker
Gut microbiota
Optimized dose selective HDAC inhibitor tucidinostat overcomes anti-PD-L1 antibody resistance in experimental solid tumors
期刊论文
OAI收割
BMC Medicine, 2022, 卷号: 20, 期号: 1
作者:
Zhang,Pei
;
Du,Yang
;
Bai,Hua
;
Wang,Zhijie
;
Duan,Jianchun
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/11/21
Tucidinostat
Tumor microenvironment
PD-L1
CCL5
Solid tumor
Chinese expert consensus on the multidisciplinary management of pneumonitis associated with immune checkpoint inhibitor
期刊论文
OAI收割
THORACIC CANCER, 2022
作者:
Wang, Wenxian
;
Wang, Qian
;
Xu, Chunwei
;
Li, Ziming
;
Song, Zhengbo
  |  
收藏
  |  
浏览/下载:37/0
  |  
提交时间:2022/12/23
checkpoint inhibitor pneumonitis
Chinese experts consensus
immune checkpoint inhibitor-related adverse effects
Neoadjuvant immunotherapy in non-small-cell lung cancer: a narrative review on mechanisms, efficacy and safety
期刊论文
OAI收割
JOURNAL OF THORACIC DISEASE, 2022
作者:
Shao, Lan
;
Lou, Guangyuan
  |  
收藏
  |  
浏览/下载:19/0
  |  
提交时间:2022/12/22
Neoadjuvant
immunotherapy
immune-checkpoint inhibitors
non-small cell lung cancer (NSCLC)
The Efficacy of PD-1/PD-L1 Inhibitors in Patients with Liver Metastasis of Non-Small Cell Lung Cancer: A Real-World Study
期刊论文
OAI收割
CANCERS, 2022, 卷号: 14
作者:
Xie, Mingying
;
Li, Na
;
Xu, Xiaoling
;
Xu, Yanjun
;
Li, Hui
  |  
收藏
  |  
浏览/下载:21/0
  |  
提交时间:2022/12/22
liver metastasis
non-small cell lung cancer
PD-L1
PD-1
PD-L1 inhibitor
CD8+T cell
Lenvatinib- and vadimezan-loaded synthetic high-density lipoprotein for combinational immunochemotherapy of metastatic triple-negative breast cancer
期刊论文
OAI收割
ACTA PHARMACEUTICA SINICA B, 2022, 卷号: 12, 期号: 9, 页码: 3726-3738
作者:
Zheng, Chao
;
Zhang, Wen
;
Wang, Jinming
;
Zhai, Yihui
;
Xiong, Fengqin
  |  
收藏
  |  
浏览/下载:34/0
  |  
提交时间:2022/12/13
KEY WORDS High-density lipoprotein
Immunotherapy
Combination therapy
Metastasis
Triple-negative breast cancer
Lenvatinib
Vadimezan
Immune checkpoint blockade