机构

• 上海药物研究所 [25]
• 动物研究所 [1]
• 上海营养与健康研究所 [1]
• 昆明动物研究所 [1]

采集方式

• OAI收割 [28]

内容类型

• 期刊论文 [28]

发表日期

• 2023 [1]
• 2022 [3]
• 2019 [1]
• 2018 [1]
• 2016 [3]
• 2015 [3]
• 更多

学科主题

筛选

浏览/检索结果: 共28条，第1-10条 帮助 条数/页： 5101520253035404550556065707580859095100 排序方式： 请选择提交时间升序提交时间降序发表日期升序发表日期降序题名升序题名降序作者升序作者降序 Ligand activation mechanisms of human KCNQ2 channel 期刊论文  OAI收割 Nature communications, 2023, 卷号: 14, 期号: 1, 页码: 6632 作者:  Ma, Demin;  Zheng, Yueming;  Li, Xiaoxiao;  Zhou, Xiaoyu;  Yang, Zhenni   |  收藏  |  浏览/下载：18/0  |  提交时间：2024/03/26 Epilepsy phenotype and response to KCNQ openers in mice harboring the Kcnq2 R207W voltage-sensor mutation 期刊论文  OAI收割 NEUROBIOLOGY OF DISEASE, 2022, 卷号: 174, 页码: 10 作者:  Tian, Fuyun;  Cao, Birong;  Xu, Haiyan;  Zhan, Li;  Nan, Fajun   |  收藏  |  浏览/下载：26/0  |  提交时间：2022/12/13 KCNQ2  Epilepsy  Mouse model  HN37 (pynegabine)   Diversity-oriented synthesis of marine polybrominated diphenyl ethers as potential KCNQ potassium channel activators 期刊论文  OAI收割 BIOORGANIC CHEMISTRY, 2022, 卷号: 126, 页码: 105909 作者:  Liu, Lai-Xin;  Gu, Ru-Rong;  Jin, Yang;  Chen, Xue-Qin;  Li, Xu-Wen   |  收藏  |  浏览/下载：7/0  |  提交时间：2024/03/21 Marine Natural product  Polybrominated diphenyl ethers  KCNQ potassium channel   General Pharmacological Activation Mechanism of K+ Channels Bypassing Channel Gates 期刊论文  OAI收割 JOURNAL OF MEDICINAL CHEMISTRY, 2022, 页码: 15 作者:  Liu, Shijie;  Guo, Peipei;  Wang, Kun;  Zhang, Shaoying;  Li, Ya   |  收藏  |  浏览/下载：39/0  |  提交时间：2022/08/30 Discovery of Novel Retigabine Derivatives as Potent KCNQ4 and KCNQ5 Channel Agonists with Improved Specificity 期刊论文  OAI收割 ACS MEDICINAL CHEMISTRY LETTERS, 2019, 卷号: 10, 期号: 1, 页码: 27-33 作者:  Wang, Lei;  Qiao, Guan-Hua;  Hu, Hai-Ning;  Gao, Zhao-Bing;  Nan, Fa-Jun   |  收藏  |  浏览/下载：27/0  |  提交时间：2020/07/01 KCNQ channel  retigabine  subtype selectivity  agonist   A Statistical Thermodynamic Model for Ligands Interacting With Ion Channels: Theoretical Model and Experimental Validation of the KCNQ2 Channel 期刊论文  OAI收割 FRONTIERS IN PHARMACOLOGY, 2018, 卷号: 9 作者:  Bai, Fang;  Pi, Xiaoping;  Li, Ping;  Zhou, Pingzheng;  Yang, Huaiyu   |  收藏  |  浏览/下载：29/0  |  提交时间：2019/01/08 KCNQ2 potassium channel  hill equation  thermodynamic model  patch clamp electrophysiology  activators   Novel KCNQ2 channel activators discovered using fluorescence-based and automated patch-clamp-based high-throughput screening techniques 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 1, 页码: 105-110 作者:  Yue, Jin-feng;  Qiao, Guan-hua;  Liu, Ni;  Chen, Xue-qin;  Nan, Fa-jun   |  收藏  |  浏览/下载：17/0  |  提交时间：2019/01/08 KCNQ2  channel activator  high-throughput screening  thallium flux assay  automated patch-clamp  ZG1732  ZG2083   KCNQ potassium channels in sensory system and neural circuits 期刊论文  OAI收割 ACTA PHARMACOLOGICA SINICA, 2016, 卷号: 37, 期号: 1, 页码: 25-33 作者:  Wang, Jing-jing;  Li, Yang   |  收藏  |  浏览/下载：15/0  |  提交时间：2019/01/08 KCNQ channels  M channels  neural circuits  channelopathy  epilepsy  neuropathic pain  deafness  mental illness   Novel KCNQ2 channel activators discovered using fluorescence-based and automated patch-clampbased high-throughput screening techniques 期刊论文  OAI收割 Acta Pharmacologica Sinica, 2016, 卷号: 37, 期号: 1, 页码: 105 作者:  Yue Jinfeng;  Qiao Guanhua;  Liu Ni;  Chen Xueqin;  Nan Fajun   |  收藏  |  浏览/下载：6/0  |  提交时间：2020/07/01 POTASSIUM CHANNEL  KV7 CHANNELS  EPILEPSY  IDENTIFICATION  GENE  KCNQ2  channel activator  high-throughput screening  thallium flux assay  automated patch-clamp  ZG1732  ZG2083   Migration of PIP2 lipids on voltage-gated potassium channel surface influences channel deactivation 期刊论文  OAI收割 SCIENTIFIC REPORTS, 2015, 卷号: 5 作者:  Chen, Liping;  Zhang, Qiansen;  Qiu, Yunguang;  Li, Zanyuan;  Chen, Zhuxi   |  收藏  |  浏览/下载：11/0  |  提交时间：2019/01/08