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浏览/检索结果: 共265条，第1-10条 帮助

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Discovery of novel isopropanolamine inhibitors against MoTPS1 as potential fungicides with unique mechanisms 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 260, 页码: 14
作者:  Jiang, Zhiyang;  Shi, Dongmei;  Chen, Yitong;  Li, Huilin;  Wang, Jin 'e
  |  收藏  |  浏览/下载：8/0  |  提交时间：2023/12/08
Biological Function of Pin1 in Vivo and Its Inhibitors for Preclinical Study: Early Development, Current Strategies, and Future Directions 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 14, 页码: 9251-9277
作者:  He, Siyu;  Li, Linjie;  Jin, Rui;  Lu, Xiaojie
  |  收藏  |  浏览/下载：14/0  |  提交时间：2023/10/17
Discovery of a New-Generation S-Adenosylmethionine-Noncompetitive Covalent Inhibitor Targeting the Lysine Methyltransferase Enhancer of Zeste Homologue 2 期刊论文  OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2023, 卷号: 66, 期号: 11, 页码: 7629-7644
作者:  Zhang, Yi;  Yang, Hong;  Li, Bingbing;  Li, Jiayi;  Li, Huaxuan
  |  收藏  |  浏览/下载：20/0  |  提交时间：2023/10/17
Discovery, synthesis and mechanism study of 2,3,5-substituted [1,2,4]-thiadiazoles as covalent inhibitors targeting 3C-Like protease of SARS-CoV-2 期刊论文  OAI收割
European journal of medicinal chemistry, 2023, 卷号: 249, 页码: 115129
作者:  Ren, Pengxuan;  Yu, Changyue;  Zhang, Ruxue;  Nie, Tianqing;  Hu, Qiaoyu
  |  收藏  |  浏览/下载：9/0  |  提交时间：2024/03/26
Design, synthesis, and biological evaluation of novel carbazole derivatives as potent DNMT1 inhibitors with reasonable PK properties 期刊论文  OAI收割
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1537-1555
作者:  Li, Ennian;  Wang, Kai;  Zhang, Bei;  Guo, Siqi;  Xiao, Senhao
  |  收藏  |  浏览/下载：37/0  |  提交时间：2022/08/16
Identification of 1H-pyrazolo[3,4-b]pyridine derivatives as novel and potent TBK1 inhibitors: design, synthesis, biological evaluation, and molecular docking study 期刊论文  OAI收割
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY, 2022, 卷号: 37, 期号: 1, 页码: 1411-1425
作者:  Sun, Yin;  Tang, Haotian;  Wang, Xiaoyan;  Feng, Fang;  Fan, Tiantian
  |  收藏  |  浏览/下载：36/0  |  提交时间：2022/08/16
Proteomic characterization of post-translational modifications in drug discovery 期刊论文  OAI收割
ACTA PHARMACOLOGICA SINICA, 2022, 页码: 18
作者:  Zhai, Lin-hui;  Chen, Kai-feng;  Hao, Bing-bing;  Tan, Min-jia
  |  收藏  |  浏览/下载：12/0  |  提交时间：2023/04/10
Design, synthesis and pharmacological evaluation of new PARP1 inhibitors by merging pharmacophores of olaparib and the natural product alantolactone 期刊论文  OAI收割
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 240, 页码: 114574
作者:  Kayumov, Muzaffar;  Jia, Li;  Pardaev, Azizbek;  Song, Shan-Shan;  Mirzaakhmedov, Sharafitdin
  |  收藏  |  浏览/下载：12/0  |  提交时间：2024/03/21
Computationally Elucidating the Binding Kinetics for Different AChE Inhibitors to Access the Rationale for Improving the Drug Efficacy 期刊论文  OAI收割
JOURNAL OF PHYSICAL CHEMISTRY B, 2022, 页码: 9
作者:  Bai, Fang;  Jiang, Hualiang
  |  收藏  |  浏览/下载：13/0  |  提交时间：2022/11/11
Systematic Review of the Role of Alpha-Protein Kinase 1 in Cancer and Cancer-Related Inflammatory Diseases 期刊论文  OAI收割
CANCERS, 2022, 卷号: 14, 期号: 18, 页码: 16
作者:  Ko, Albert Min-Shan;  Tu, Hung-Pin;  Ko, Ying-Chin
  |  收藏  |  浏览/下载：21/0  |  提交时间：2022/12/02