中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
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CAS IR Grid
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上海药物研究所 [18]
武汉病毒研究所 [5]
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使用机器学习来预测迟发性运动障碍的发生及银杏叶的治 疗反应
学位论文
OAI收割
中国科学院心理研究所: 中国科学院大学, 2023
作者:
ULUDAG KADIR
  |  
收藏
  |  
浏览/下载:11/0
  |  
提交时间:2023/05/16
机器学习
迟发性运动障碍预测
遗传学
生物标志物
抗精神病药物类型
Structure-Activity Relationship Study of Indolin-5-yl-cyclopropanamine Derivatives as Selective Lysine Specific Demethylase 1 (LSD1) Inhibitors
期刊论文
OAI收割
JOURNAL OF MEDICINAL CHEMISTRY, 2022, 卷号: 65, 期号: 5, 页码: 4335-4349
作者:
Li, Chunpu
;
Su, Mingbo
;
Zhu, Wei
;
Kan, Weijuan
;
Ge, Tianpeng
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2022/06/15
Small-molecule fluorescence-based probes for interrogating major organ diseases
期刊论文
OAI收割
CHEMICAL SOCIETY REVIEWS, 2021, 页码: 39
作者:
Han, Hai-Hao
;
Tian, He, Jr.
;
Zang, Yi
;
Sedgwick, Adam C.
;
Li, Jia
  |  
收藏
  |  
浏览/下载:24/0
  |  
提交时间:2021/08/17
Recent advances in dopaminergic strategies for the treatment of Parkinson's disease
期刊论文
OAI收割
ACTA PHARMACOLOGICA SINICA, 2020, 页码: 12
作者:
Mao, Qi
;
Qin, Wang-zhi
;
Zhang, Ao
;
Ye, Na
  |  
收藏
  |  
浏览/下载:20/0
  |  
提交时间:2020/07/01
Parkinson's disease
dopamine
D-1 receptor
D-2 receptor
allosteric modulator
neuroprotection
multitarget
drug discovery and development
neurodegenerative diseases
Identification of novel monoamine oxidase selective inhibitors employing a hierarchical ligand-based virtual screening strategy
期刊论文
OAI收割
FUTURE MEDICINAL CHEMISTRY, 2019, 卷号: 11, 期号: 8, 页码: 801-816
作者:
Wang, Dong
;
Li, Zhaoyang
;
Liu, Yi
;
Chen, Mo
;
Chen, Nianhang
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2019/09/10
BRS-3D
monoamine oxidase selective inhibitors
virtual screening
Rational Design of Novel Selective Dual-Target Inhibitors of Acetylcholinesterase and Monoamine Oxidase B as Potential Anti-Alzheimer's Disease Agents
期刊论文
OAI收割
ACS chemical neuroscience, 2018
作者:
Xu, Yixiang
;
Zhang, Jian
;
Wang, Huan
;
Mao, Fei
;
Bao, Keting
  |  
收藏
  |  
浏览/下载:83/0
  |  
提交时间:2019/01/08
Ratiometric Near-Infrared Fluorescent Probe for Synergistic Detection of Monoamine Oxidase B and Its Contribution to Oxidative Stress in Cell and Mice Aging Models
期刊论文
OAI收割
ANALYTICAL CHEMISTRY, 2018, 卷号: 90, 期号: 6, 页码: 4054-4061
作者:
Wang, Rui
;
Han, Xiaoyue
;
You, Jinmao
;
Yu, Fabiao
;
Chen, Lingxin
  |  
收藏
  |  
浏览/下载:31/0
  |  
提交时间:2018/09/19
The cholinergic and adrenergic autocrine signaling Pathway Mediates immunomodulation in Oyster Crassostrea gigas
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2018, 卷号: 9
作者:
Liu, Zhaoqun
;
Wang, Lingling
;
Lv, Zhao
;
Zhou, Zhi
;
Wang, Weilin
  |  
收藏
  |  
浏览/下载:46/0
  |  
提交时间:2018/09/06
Crassostrea Gigas
Autocrine/paracrine
Hemocyte
Neurotransmitter
Membrane Receptor
Immune Regulation
The cholinergic and adrenergic autocrine signaling Pathway Mediates immunomodulation in Oyster Crassostrea gigas
期刊论文
OAI收割
FRONTIERS IN IMMUNOLOGY, 2018, 卷号: 9
作者:
Liu, Zhaoqun
;
Wang, Lingling
;
Lv, Zhao
;
Zhou, Zhi
;
Wang, Weilin
  |  
收藏
  |  
浏览/下载:43/0
  |  
提交时间:2018/04/02
Crassostrea Gigas
Autocrine/paracrine
Hemocyte
Neurotransmitter
Membrane Receptor
Immune Regulation
Design, Synthesis, and Biological Evaluation of Orally Available First-Generation Dual-Target Selective Inhibitors of Acetylcholinesterase (AChE) and Phosphodiesterase 5 (PDE5) for the Treatment of Alzheimer's Disease
期刊论文
OAI收割
ACS CHEMICAL NEUROSCIENCE, 2018, 卷号: 9, 期号: 2, 页码: 328-345
作者:
Mao, Fei
;
Wang, Huan
;
Ni, Wei
;
Zheng, Xinyu
;
Wang, Manjiong
  |  
收藏
  |  
浏览/下载:56/0
  |  
提交时间:2019/01/08
Alzheimer's disease
drug repositioning
dual-target inhibitor
AChE inhibition
PDE5 inhibition